CA2398184A1 - Method and compositions for treating an inflammatory disease - Google Patents

Method and compositions for treating an inflammatory disease Download PDF

Info

Publication number
CA2398184A1
CA2398184A1 CA002398184A CA2398184A CA2398184A1 CA 2398184 A1 CA2398184 A1 CA 2398184A1 CA 002398184 A CA002398184 A CA 002398184A CA 2398184 A CA2398184 A CA 2398184A CA 2398184 A1 CA2398184 A1 CA 2398184A1
Authority
CA
Canada
Prior art keywords
pde
rolipram
sodium
inhibitor
pde4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002398184A
Other languages
English (en)
French (fr)
Inventor
Elizabeth T. Keating
James M. Kanagy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2398184A1 publication Critical patent/CA2398184A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002398184A 2000-02-08 2001-02-08 Method and compositions for treating an inflammatory disease Abandoned CA2398184A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18087900P 2000-02-08 2000-02-08
US60/180,879 2000-02-08
PCT/US2001/003972 WO2001058441A1 (en) 2000-02-08 2001-02-08 Method and compositions for treating an inflammatory disease

Publications (1)

Publication Number Publication Date
CA2398184A1 true CA2398184A1 (en) 2001-08-16

Family

ID=22662062

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002398184A Abandoned CA2398184A1 (en) 2000-02-08 2001-02-08 Method and compositions for treating an inflammatory disease

Country Status (16)

Country Link
EP (1) EP1253919A4 (xx)
JP (1) JP2003522142A (xx)
KR (1) KR20020073577A (xx)
CN (1) CN1398181A (xx)
AU (1) AU7205701A (xx)
BR (1) BR0108087A (xx)
CA (1) CA2398184A1 (xx)
CZ (1) CZ20022682A3 (xx)
HK (1) HK1051319A1 (xx)
HU (1) HUP0300689A3 (xx)
IL (1) IL150963A0 (xx)
MX (1) MXPA02007688A (xx)
NO (1) NO20023737L (xx)
PL (1) PL356447A1 (xx)
WO (1) WO2001058441A1 (xx)
ZA (1) ZA200206252B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7338971B2 (en) 2001-08-30 2008-03-04 El-Naggar Mawaheb M Treatment of inflammatory, cancer, and thrombosis disorders
DE60218497T2 (de) 2001-09-19 2007-11-08 Nycomed Gmbh Kombination eines nsaids und eines pde-4 inhibitors
WO2003037349A1 (en) * 2001-10-31 2003-05-08 Merck Patent Gmbh Type 4 phosphodiesterase inhibitors and uses thereof
WO2004098605A1 (en) * 2003-05-12 2004-11-18 Altana Pharma Ag Pharmaceutical composition comprising a pde4 inhibitor and il-1 trap
WO2005020926A2 (en) * 2003-08-28 2005-03-10 Pharmacia Corporation Treatment or prevention of vascular disorders with cox-2 inhibitors in combination with cyclic amp-specific phosphodiesterase inhibitors
WO2010097334A1 (de) * 2009-02-27 2010-09-02 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen enthaltend pde4-inhibitoren und nsaids
CA2753597A1 (en) * 2009-02-27 2010-09-02 Boehringer Ingelheim International Gmbh Drug combinations containing pde4-inhibitors and nsaids
SG186989A1 (en) 2010-07-14 2013-02-28 Novartis Ag Ip receptor agonist heterocyclic compounds
AR089698A1 (es) 2012-01-13 2014-09-10 Novartis Ag Compuestos heterociclicos antagonistas del receptor ip
US9604981B2 (en) 2013-02-13 2017-03-28 Novartis Ag IP receptor agonist heterocyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061779A (en) * 1973-09-11 1977-12-06 Beecham Group Limited Naphthalene derivatives having anti-inflammatory activity
GB9108128D0 (en) * 1991-04-15 1991-06-05 Zambeletti Spa L Novel formulation
CZ283425B6 (cs) * 1992-04-02 1998-04-15 Smithkline Beecham Corporation Fenylové deriváty a farmaceutické prostředky s jejich obsahem
US6005118A (en) * 1996-05-03 1999-12-21 Caron; Stephane Methods of preparing 4-cyano-4 (substituted indazole) cyclohexane-carboxylic acids useful as PDE4 inhibitors
FR2753706B1 (fr) * 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
WO2001058441A1 (en) 2001-08-16
NO20023737D0 (no) 2002-08-07
HK1051319A1 (zh) 2003-08-01
AU7205701A (en) 2001-08-20
CN1398181A (zh) 2003-02-19
HUP0300689A2 (hu) 2003-07-28
BR0108087A (pt) 2002-10-29
KR20020073577A (ko) 2002-09-27
IL150963A0 (en) 2003-02-12
CZ20022682A3 (cs) 2003-09-17
ZA200206252B (en) 2003-08-26
NO20023737L (no) 2002-09-27
MXPA02007688A (es) 2002-12-13
EP1253919A4 (en) 2007-03-14
HUP0300689A3 (en) 2003-09-29
EP1253919A1 (en) 2002-11-06
PL356447A1 (en) 2004-06-28
JP2003522142A (ja) 2003-07-22

Similar Documents

Publication Publication Date Title
US6288118B1 (en) Therapies for treating pulmonary diseases
CA1258430A (en) Cough/cold mixtures comprising non-steroidal anti- inflammatory drugs
JP2004538302A (ja) 新規治療方法
CZ20023381A3 (cs) Kombinované farmaceutické prostředky obsahující antagonistu AT1-receptoru nebo/a inhibitor HMG-CoA reduktázy nebo/a ACE inhibitor
KR20070032619A (ko) 폐동맥 고혈압의 치료를 위한 일로프로스트의 복합 치료제
CA2398184A1 (en) Method and compositions for treating an inflammatory disease
US20040176419A1 (en) Composition comprising a pde-4 inhibitor and h1-receptor antagonist and the use thereof for the manufacture of a medicament for the treatment of respiratory diseases
NZ506020A (en) Use of pharmaceutical combinations containing tramadol and an antiemetic
US20030207845A1 (en) Method and compositions for treating an inflammatory disease
CA2388333A1 (en) Method and compositions for treating pulmonary diseases
EP1261331A1 (en) Method and compositions for treating fibrotic diseases
AU2004240185A1 (en) Method and compositions for treating an inflammatory disease
US20030018071A1 (en) Method and compositions for treating fibrotic diseases
Haggerty Jr et al. Use of psychotropic drugs in patients with peptic ulcer
AU2002310620A1 (en) Composition comprising a PDE-4 inhibitor and H1-receptor antagonist and the use thereof for the manufacture of a medicament for the treatment respiratory diseases
CA2527190A1 (en) Combination of acetylsalicylic acid and alpha-glucosidase inhibitors
MXPA01001994A (en) Therapies for treating pulmonary diseases

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued