BR0108087A - Método e composições para o tratamento de uma doença inflamatória - Google Patents

Método e composições para o tratamento de uma doença inflamatória

Info

Publication number
BR0108087A
BR0108087A BR0108087-3A BR0108087A BR0108087A BR 0108087 A BR0108087 A BR 0108087A BR 0108087 A BR0108087 A BR 0108087A BR 0108087 A BR0108087 A BR 0108087A
Authority
BR
Brazil
Prior art keywords
treatment
inflammatory disease
compositions
inhibitor
phosphodistearase
Prior art date
Application number
BR0108087-3A
Other languages
English (en)
Inventor
Elizabeth T Keating
James M Kanagy
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BR0108087A publication Critical patent/BR0108087A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"MéTODO E COMPOSIçõES PARA O TRATAMENTO DE UMA DOENçA INFLAMATóRIA". Essa invenção se refere ao tratamento de uma doença inflamatória mediante a administração de um inibidor de fosfodiestearase 4 em combinação com um inibidor da síntese de prostaglandina, as NSAIDs sendo exemplares.
BR0108087-3A 2000-02-08 2001-02-08 Método e composições para o tratamento de uma doença inflamatória BR0108087A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18087900P 2000-02-08 2000-02-08
PCT/US2001/003972 WO2001058441A1 (en) 2000-02-08 2001-02-08 Method and compositions for treating an inflammatory disease

Publications (1)

Publication Number Publication Date
BR0108087A true BR0108087A (pt) 2002-10-29

Family

ID=22662062

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0108087-3A BR0108087A (pt) 2000-02-08 2001-02-08 Método e composições para o tratamento de uma doença inflamatória

Country Status (16)

Country Link
EP (1) EP1253919A4 (pt)
JP (1) JP2003522142A (pt)
KR (1) KR20020073577A (pt)
CN (1) CN1398181A (pt)
AU (1) AU7205701A (pt)
BR (1) BR0108087A (pt)
CA (1) CA2398184A1 (pt)
CZ (1) CZ20022682A3 (pt)
HK (1) HK1051319A1 (pt)
HU (1) HUP0300689A3 (pt)
IL (1) IL150963A0 (pt)
MX (1) MXPA02007688A (pt)
NO (1) NO20023737L (pt)
PL (1) PL356447A1 (pt)
WO (1) WO2001058441A1 (pt)
ZA (1) ZA200206252B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7338971B2 (en) * 2001-08-30 2008-03-04 El-Naggar Mawaheb M Treatment of inflammatory, cancer, and thrombosis disorders
PL210463B1 (pl) * 2001-09-19 2012-01-31 Nycomed Gmbh Zastosowanie kombinacji roflumilastu z diklofenakiem w leczeniu zapalnych chorób stawów
EP1463509A1 (en) * 2001-10-31 2004-10-06 MERCK PATENT GmbH Type 4 phosphodiesterase inhibitors and uses thereof
WO2004098605A1 (en) * 2003-05-12 2004-11-18 Altana Pharma Ag Pharmaceutical composition comprising a pde4 inhibitor and il-1 trap
WO2005020926A2 (en) * 2003-08-28 2005-03-10 Pharmacia Corporation Treatment or prevention of vascular disorders with cox-2 inhibitors in combination with cyclic amp-specific phosphodiesterase inhibitors
WO2010097334A1 (de) * 2009-02-27 2010-09-02 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen enthaltend pde4-inhibitoren und nsaids
EP2400961B1 (de) * 2009-02-27 2017-11-22 Boehringer Ingelheim International GmbH Arzneimittelkombinationen enthaltend pde4-inhibitoren und nsaids
EA022046B1 (ru) 2010-07-14 2015-10-30 Новартис Аг Гетероциклические соединения, агонисты рецептора ip
TW201335160A (zh) 2012-01-13 2013-09-01 Novartis Ag Ｉｐ受體激動劑之雜環化合物
ES2637719T3 (es) 2013-02-13 2017-10-16 Novartis Ag Compuestos heterocíclicos agonistas del receptor IP

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061779A (en) * 1973-09-11 1977-12-06 Beecham Group Limited Naphthalene derivatives having anti-inflammatory activity
GB9108128D0 (en) * 1991-04-15 1991-06-05 Zambeletti Spa L Novel formulation
AU677776B2 (en) * 1992-04-02 1997-05-08 Smithkline Beecham Corporation Compounds useful for treating allergic and inflammatory diseases
US6005118A (en) * 1996-05-03 1999-12-21 Caron; Stephane Methods of preparing 4-cyano-4 (substituted indazole) cyclohexane-carboxylic acids useful as PDE4 inhibitors
FR2753706B1 (fr) * 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
HUP0300689A2 (hu) 2003-07-28
ZA200206252B (en) 2003-08-26
CA2398184A1 (en) 2001-08-16
HUP0300689A3 (en) 2003-09-29
HK1051319A1 (zh) 2003-08-01
MXPA02007688A (es) 2002-12-13
NO20023737L (no) 2002-09-27
KR20020073577A (ko) 2002-09-27
NO20023737D0 (no) 2002-08-07
CZ20022682A3 (cs) 2003-09-17
PL356447A1 (en) 2004-06-28
AU7205701A (en) 2001-08-20
EP1253919A1 (en) 2002-11-06
CN1398181A (zh) 2003-02-19
WO2001058441A1 (en) 2001-08-16
IL150963A0 (en) 2003-02-12
EP1253919A4 (en) 2007-03-14
JP2003522142A (ja) 2003-07-22

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]