CA2395493C - Hyaluronic acid in the treatment of cancer - Google Patents

Hyaluronic acid in the treatment of cancer Download PDF

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Publication number
CA2395493C
CA2395493C CA2395493A CA2395493A CA2395493C CA 2395493 C CA2395493 C CA 2395493C CA 2395493 A CA2395493 A CA 2395493A CA 2395493 A CA2395493 A CA 2395493A CA 2395493 C CA2395493 C CA 2395493C
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CA
Canada
Prior art keywords
dna
grou
bacterial
cancer
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2395493A
Other languages
English (en)
French (fr)
Other versions
CA2395493A1 (en
Inventor
Mario C. Filion
Nigel C. Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telesta Therapeutics IP Inc
Original Assignee
Bioniche Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioniche Life Sciences Inc filed Critical Bioniche Life Sciences Inc
Publication of CA2395493A1 publication Critical patent/CA2395493A1/en
Application granted granted Critical
Publication of CA2395493C publication Critical patent/CA2395493C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA2395493A 1999-12-28 2000-12-28 Hyaluronic acid in the treatment of cancer Expired - Fee Related CA2395493C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17337599P 1999-12-28 1999-12-28
US60/173,375 1999-12-28
PCT/CA2000/001562 WO2001047561A1 (en) 1999-12-28 2000-12-28 Hyaluronic acid in the treatment of cancer

Publications (2)

Publication Number Publication Date
CA2395493A1 CA2395493A1 (en) 2001-07-05
CA2395493C true CA2395493C (en) 2010-06-22

Family

ID=22631719

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2395493A Expired - Fee Related CA2395493C (en) 1999-12-28 2000-12-28 Hyaluronic acid in the treatment of cancer

Country Status (8)

Country Link
US (1) US7125858B2 (enExample)
EP (1) EP1250152B1 (enExample)
JP (1) JP4215429B2 (enExample)
AU (1) AU784356B2 (enExample)
CA (1) CA2395493C (enExample)
DK (1) DK1250152T3 (enExample)
NZ (1) NZ520312A (enExample)
WO (1) WO2001047561A1 (enExample)

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DE60036915T2 (de) 1999-01-13 2008-08-07 Alchemia Oncology Pty Ltd., Hawthorn Verwendung von hyaluronan zur herstellung eines medikaments zur erhöhung der wirksamkeit von zytotoxischen arzneimitteln
PT1238070E (pt) * 1999-12-13 2007-11-06 Bioniche Life Sciences Inc Oligonucleótidos sintéticos úteis sob o ponto de vista terapêutico
US20020091095A1 (en) * 1999-12-13 2002-07-11 Phillips Nigel C. Modulation of Fas and FasL expression
US9066919B2 (en) 2000-07-14 2015-06-30 Alchemia Oncology Pty Limited Hyaluronan as a chemo-sensitizer in the treatment of cancer
AUPQ879500A0 (en) * 2000-07-14 2000-08-10 Meditech Research Limited Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease
US8039602B2 (en) 2000-10-31 2011-10-18 Ryogen Llc Isolated genomic polynucleotide fragments from the p15 region of chromosome 11
US7087586B2 (en) * 2001-04-24 2006-08-08 Bioniche Life Sciences, Inc. Oligonucleotide compositions and their use to induce differentiation of cells
ITPD20020271A1 (it) 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
JP4851185B2 (ja) 2003-05-16 2012-01-11 ジェレックスインターナショナル株式会社 アレルギー症状抑制剤及び空気濾過フィルター
US20060240084A1 (en) * 2005-04-20 2006-10-26 Xylos Corporation Microbial cellulose materials for use in transdermal drug delivery systems, method of manufacture and use
AU2006274509B2 (en) * 2005-07-27 2012-01-19 Alchemia Oncology Pty Limited Therapeutic protocols using hyaluronan
CN101287475B (zh) * 2005-09-07 2012-11-14 阿尔卡米亚肿瘤学股份有限公司 包含透明质酸和治疗抗体的治疗组合物以及制药用途
WO2008070538A2 (en) 2006-12-01 2008-06-12 Anterios, Inc. Micellar nanoparticles comprising botulinum toxin
DE102009035586A1 (de) 2009-07-31 2011-02-03 Fresenius Kabi Deutschland Gmbh Intravesikale Instillationslösungen zur Behandlung von Blasenkrebs
KR101802540B1 (ko) 2009-09-25 2017-11-28 큐알엔에이, 인크. Ｆｌｇ의 발현 및 활성을 조절함으로써 필라그린(ｆｌｇ)에 관련된 질환의 치료
AU2011315093B2 (en) 2010-10-13 2013-10-17 Telesta Therapeutics Ip Inc. Bacterial ribonucleic acid cell wall compositions and methods of making and using them
EP3044614A1 (en) * 2013-09-12 2016-07-20 DSM IP Assets B.V. Ocular device
EP3541358A1 (en) 2016-11-21 2019-09-25 Eirion Therapeutics, Inc. Transdermal delivery of large agents
WO2020252003A1 (en) 2019-06-13 2020-12-17 Hollister Incorporated Reusable urinary catheter products
US12440644B2 (en) 2019-06-25 2025-10-14 Hollister Incorporated Reusable urinary catheter products
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
JP7500038B2 (ja) * 2019-08-27 2024-06-17 国立研究開発法人物質・材料研究機構 炎症性サイトカイン産生抑制材、ヒアルロン酸誘導体、及び、ヒアルロン酸誘導体の製造方法。
CN115776909A (zh) * 2020-07-17 2023-03-10 美国杰龙生物医药公司 皮下端粒酶抑制剂组合物及其使用方法
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof

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US3172815A (en) * 1962-04-24 1965-03-09 Warner Lambert Pharmaceutical Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof
FR2160326B1 (enExample) * 1971-11-19 1975-02-07 Anvar
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FR2374042A1 (fr) * 1976-06-04 1978-07-13 Merieux Inst Nouveau medicament immunostimulant et son procede de preparation
JPS54140710A (en) * 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
DE3011461C2 (de) * 1980-03-25 1986-10-30 Dr. Madaus & Co, 5000 Köln Verwendung von Propionibakterien
US4520019A (en) * 1982-04-29 1985-05-28 Ribi Immunochem Research, Inc. Stable composition and preparation thereof
US4579941A (en) * 1982-08-13 1986-04-01 Mitsuitoatsu Chemicals, Inc. Thermally-denatured deoxyribonucleic acid MD-011 and antitumor agent
US4663306A (en) * 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
GB8404280D0 (en) * 1984-02-17 1984-03-21 Stanford J L Biological preparations
DE3408768A1 (de) 1984-03-09 1985-09-12 Bayer Ag, 5090 Leverkusen Immunstimulierende mittel
US4744984A (en) * 1985-10-08 1988-05-17 Vetrepharm Research, Inc. Antiviral immunotherapeutic agent and preparation thereof
JPH0725683B2 (ja) 1985-10-31 1995-03-22 ザ オ−ストラリアン ナシヨナル ユニバ−シテイ− 免疫治療方法
US4877611A (en) * 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
US4837202A (en) 1987-09-14 1989-06-06 Pitman-Moore, Inc. Method for stimulating the immune system
DE3818054C2 (de) 1988-05-27 1994-02-17 Biotest Pharma Gmbh Verwendung einer Kombination aus einem Antigen bzw. einer Vakzine und humanem Interleukin zur Behandlung der Non-Responsiveness gegenüber immunologischen Defektzuständen
CA1340994C (en) * 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Treatment of conditions and disease
WO1998017320A1 (en) 1991-07-03 1998-04-30 Hyal Pharmaceutical Corporation Use of hyaluronan in gene therapy
CA2122519C (en) 1994-04-29 2001-02-20 Rudolf Edgar Dr. Falk Cancer treatment and metastasis prevention
AU691797B2 (en) 1993-01-29 1998-05-28 Vetrepharm, Inc. Immunotherapeutic composition
AU6362594A (en) * 1993-03-10 1994-09-26 Miles Inc. Hyaluronic acid used as a cancer treatment
IN181358B (enExample) * 1995-02-14 1998-05-30 Bioniche Inc
WO1997033612A1 (en) 1996-03-15 1997-09-18 Immunotherapy, Inc. Dialdehydes as immunostimulatory adjuvants and cross-linkers for producing immunogenic preparations and generating pressure and cross-link treated cells for enhancing and augmenting the immune response against cancers, tumors and pathogenic diseases
CA2208924A1 (en) 1997-07-09 1999-01-09 Hyal Pharmaceutical Corporation Sparing paclitaxel by the use of hyaluronan
JP4335435B2 (ja) * 1997-08-05 2009-09-30 バイオニケ ライフ サイエンシーズ インコーポレイテッド 細胞増殖および細胞死を調節する組成物および方法
DE69829316T2 (de) 1998-02-18 2006-04-13 Bioniche Life Sciences Inc., Belleville Behandlung des harnblasenkrebses durch mycobacterium phlei zellwand
WO2000033875A1 (en) 1998-12-04 2000-06-15 Bioniche Life Sciences Inc. Chemotherapeutic composition and method
DE60036915T2 (de) 1999-01-13 2008-08-07 Alchemia Oncology Pty Ltd., Hawthorn Verwendung von hyaluronan zur herstellung eines medikaments zur erhöhung der wirksamkeit von zytotoxischen arzneimitteln
CA2266188A1 (en) 1999-03-19 2000-09-19 Stephen Chizick Natural preparation for treatment of male pattern hair loss

Also Published As

Publication number Publication date
NZ520312A (en) 2003-08-29
DK1250152T3 (da) 2013-08-26
WO2001047561A1 (en) 2001-07-05
AU2336401A (en) 2001-07-09
AU784356B2 (en) 2006-03-16
EP1250152A1 (en) 2002-10-23
US20030176381A1 (en) 2003-09-18
JP4215429B2 (ja) 2009-01-28
US7125858B2 (en) 2006-10-24
CA2395493A1 (en) 2001-07-05
EP1250152B1 (en) 2013-05-15
JP2003518510A (ja) 2003-06-10

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Effective date: 20151229