CA2391416A1 - Oncolytic combinations for the treatment of cancer - Google Patents

Oncolytic combinations for the treatment of cancer Download PDF

Info

Publication number
CA2391416A1
CA2391416A1 CA002391416A CA2391416A CA2391416A1 CA 2391416 A1 CA2391416 A1 CA 2391416A1 CA 002391416 A CA002391416 A CA 002391416A CA 2391416 A CA2391416 A CA 2391416A CA 2391416 A1 CA2391416 A1 CA 2391416A1
Authority
CA
Canada
Prior art keywords
ethyl
propoxy
fluorophenyl
hydroxyphenoxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002391416A
Other languages
English (en)
French (fr)
Inventor
Jerome Herbert Fleisch
William Thomas Mcmillen
Beverly Ann Teicher
Jason Scott Sawyer
Douglas Wade Beight
Edward C. R. Smith
Roger Stuart Benjamin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2391416A1 publication Critical patent/CA2391416A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
CA002391416A 1999-11-11 2000-11-09 Oncolytic combinations for the treatment of cancer Abandoned CA2391416A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16478699P 1999-11-11 1999-11-11
US60/164,786 1999-11-11
PCT/US2000/031039 WO2001034137A2 (en) 1999-11-11 2000-11-09 Oncolytic combinations for the treatment of cancer

Publications (1)

Publication Number Publication Date
CA2391416A1 true CA2391416A1 (en) 2001-05-17

Family

ID=22596085

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002391416A Abandoned CA2391416A1 (en) 1999-11-11 2000-11-09 Oncolytic combinations for the treatment of cancer

Country Status (22)

Country Link
EP (1) EP1231938A2 (ja)
JP (1) JP2003513916A (ja)
KR (1) KR20020069512A (ja)
CN (1) CN1390139A (ja)
AR (1) AR032432A1 (ja)
AU (1) AU778829B2 (ja)
BR (1) BR0015490A (ja)
CA (1) CA2391416A1 (ja)
CZ (1) CZ20021551A3 (ja)
EA (1) EA200200545A1 (ja)
HK (1) HK1050132A1 (ja)
HU (1) HUP0204449A3 (ja)
IL (1) IL148579A0 (ja)
MX (1) MXPA02004733A (ja)
NO (1) NO20022245L (ja)
NZ (1) NZ517667A (ja)
PE (1) PE20010701A1 (ja)
PL (1) PL355172A1 (ja)
SK (1) SK6492002A3 (ja)
TR (1) TR200201245T2 (ja)
WO (1) WO2001034137A2 (ja)
ZA (1) ZA200202822B (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6797723B1 (en) 1999-11-11 2004-09-28 Eli Lilly And Company Heterocycle substituted diphenyl leukotriene antagonists
WO2001034197A2 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
AU1916601A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
JP2001247459A (ja) 2000-03-03 2001-09-11 Oakland Uniservices Ltd 癌の組み合わせ療法
KR20030019372A (ko) * 2000-05-09 2003-03-06 크레이톤 유니버시티 암세포의 증식 억제 및 세포사멸 유도 방법
WO2002009700A1 (en) 2000-07-28 2002-02-07 Cancer Research Technology Limited Cancer treatment by combination therapy
GB0121285D0 (en) 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
GB2386836B (en) 2002-03-22 2006-07-26 Cancer Res Ventures Ltd Anti-cancer combinations
GB2394658A (en) 2002-11-01 2004-05-05 Cancer Rec Tech Ltd Oral anti-cancer composition
JP2007536343A (ja) 2004-05-05 2007-12-13 ノボ ノルディスク アクティーゼルスカブ Pparアゴニストとしてのフェノキシ酢酸誘導体
JP4981662B2 (ja) 2004-05-05 2012-07-25 ハイ・ポイント・ファーマスーティカルズ、エルエルシー 新規の化合物、その製法と使用
CN1302782C (zh) * 2005-01-17 2007-03-07 北京京卫燕康药物研究所有限公司 盐酸吉西他滨溶液型注射剂
KR101333101B1 (ko) 2005-06-30 2013-11-26 하이 포인트 파마슈티칼스, 엘엘씨 Ppar-델타 활성제로서의 페녹시 아세트산
EP1979311B1 (en) 2005-12-22 2012-06-13 High Point Pharmaceuticals, LLC Phenoxy acetic acids as ppar delta activators
CA2645719A1 (en) 2006-03-09 2007-09-13 High Point Pharmaceuticals, Llc Compounds that modulate ppar activity, their preparation and use
WO2008044729A1 (en) 2006-10-12 2008-04-17 Institute Of Medicinal Molecular Design. Inc. Carboxylic acid derivative
US8633245B2 (en) 2008-04-11 2014-01-21 Institute Of Medicinal Molecular Design, Inc. PAI-1 inhibitor
WO2014060381A1 (de) 2012-10-18 2014-04-24 Bayer Cropscience Ag Heterocyclische verbindungen als schädlingsbekämpfungsmittel
WO2014067962A1 (de) 2012-10-31 2014-05-08 Bayer Cropscience Ag Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
CN103319466B (zh) * 2013-07-04 2016-03-16 郑州大学 含香豆素母核的1,2,3-三唑-氨基二硫代甲酸酯化合物、制备方法及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation

Also Published As

Publication number Publication date
HUP0204449A2 (hu) 2003-04-28
EP1231938A2 (en) 2002-08-21
AU778829B2 (en) 2004-12-23
HUP0204449A3 (en) 2006-02-28
EA200200545A1 (ru) 2002-12-26
IL148579A0 (en) 2002-09-12
KR20020069512A (ko) 2002-09-04
CZ20021551A3 (cs) 2003-02-12
TR200201245T2 (tr) 2004-08-23
NO20022245D0 (no) 2002-05-10
PE20010701A1 (es) 2001-07-07
JP2003513916A (ja) 2003-04-15
NO20022245L (no) 2002-07-09
HK1050132A1 (zh) 2003-06-13
BR0015490A (pt) 2002-07-09
SK6492002A3 (en) 2003-09-11
ZA200202822B (en) 2003-09-23
AU1599001A (en) 2001-06-06
MXPA02004733A (es) 2002-08-30
WO2001034137A2 (en) 2001-05-17
WO2001034137A3 (en) 2002-02-14
PL355172A1 (en) 2004-04-05
CN1390139A (zh) 2003-01-08
NZ517667A (en) 2004-05-28
AR032432A1 (es) 2003-11-12

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Legal Events

Date Code Title Description
FZDE Discontinued