CA2386845A1 - Hydrochlorure de benzamide n-¬3-¬¬2-(3,4-dimethexyphenyl)ethyl|amino|propyl|-4-nitro polymorphe - Google Patents

Hydrochlorure de benzamide n-¬3-¬¬2-(3,4-dimethexyphenyl)ethyl|amino|propyl|-4-nitro polymorphe Download PDF

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Publication number
CA2386845A1
CA2386845A1 CA002386845A CA2386845A CA2386845A1 CA 2386845 A1 CA2386845 A1 CA 2386845A1 CA 002386845 A CA002386845 A CA 002386845A CA 2386845 A CA2386845 A CA 2386845A CA 2386845 A1 CA2386845 A1 CA 2386845A1
Authority
CA
Canada
Prior art keywords
polymorphic form
propyl
ethyl
novel polymorphic
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002386845A
Other languages
English (en)
Inventor
David Busby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Laboratoires Pharmaceutiques
SmithKline Beecham Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2386845A1 publication Critical patent/CA2386845A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La présente invention concerne une forme polymorphe d'hydrochlorure de benzamide N-[3-[[2-(3,4-diméthexyphényl)éthyl]amino]propyl]-4-nitro, un procédé permettant la préparation d'un composé de ce type et l'utilisation d'un composé de ce type dans des médicaments.
CA002386845A 1999-10-08 2000-10-06 Hydrochlorure de benzamide n-¬3-¬¬2-(3,4-dimethexyphenyl)ethyl|amino|propyl|-4-nitro polymorphe Abandoned CA2386845A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9923933.7 1999-10-08
GBGB9923933.7A GB9923933D0 (en) 1999-10-08 1999-10-08 Novel pharmaceutical
PCT/GB2000/003847 WO2001027071A1 (fr) 1999-10-08 2000-10-06 Hydrochlorure de benzamide n-[3-[[2-(3,4-dimethexyphenyl)ethyl]amino]propyl]-4-nitro polymorphe

Publications (1)

Publication Number Publication Date
CA2386845A1 true CA2386845A1 (fr) 2001-04-19

Family

ID=10862442

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002386845A Abandoned CA2386845A1 (fr) 1999-10-08 2000-10-06 Hydrochlorure de benzamide n-¬3-¬¬2-(3,4-dimethexyphenyl)ethyl|amino|propyl|-4-nitro polymorphe

Country Status (18)

Country Link
EP (1) EP1218334A1 (fr)
JP (1) JP2003511437A (fr)
KR (1) KR20020043618A (fr)
CN (1) CN1384817A (fr)
AU (1) AU7546000A (fr)
BR (1) BR0014591A (fr)
CA (1) CA2386845A1 (fr)
CZ (1) CZ20021189A3 (fr)
GB (1) GB9923933D0 (fr)
HK (1) HK1049147A1 (fr)
HU (1) HUP0203582A2 (fr)
IL (1) IL148966A0 (fr)
MX (1) MXPA02003516A (fr)
NO (1) NO20021639L (fr)
PL (1) PL354137A1 (fr)
TR (1) TR200200949T2 (fr)
WO (1) WO2001027071A1 (fr)
ZA (1) ZA200202679B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4508646B2 (ja) 2002-01-09 2010-07-21 エミスフェアー・テクノロジーズ・インク ４−［（４−クロロ−２−ヒドロキシベンゾイル）アミノ］ブタン酸ナトリウムの多形体
PL2091910T3 (pl) * 2006-12-06 2015-02-27 Conatus Pharmaceuticals Inc Postacie krystaliczne kwasu (3S)-3-[N-(N’-(2-tert-butylofenylo)oksamylo)alaninylo]amino-5-(2’,3’,5’,6’-tetrafluorofenoksy)-4-oksopentanowego

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2726267B1 (fr) * 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
GB9706376D0 (en) * 1997-03-27 1997-05-14 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
AU7546000A (en) 2001-04-23
CZ20021189A3 (cs) 2002-09-11
BR0014591A (pt) 2002-06-11
GB9923933D0 (en) 1999-12-08
CN1384817A (zh) 2002-12-11
HUP0203582A2 (en) 2004-03-01
NO20021639L (no) 2002-05-30
TR200200949T2 (tr) 2002-08-21
HK1049147A1 (zh) 2003-05-02
EP1218334A1 (fr) 2002-07-03
WO2001027071A1 (fr) 2001-04-19
NO20021639D0 (no) 2002-04-05
KR20020043618A (ko) 2002-06-10
ZA200202679B (en) 2003-05-28
IL148966A0 (en) 2002-11-10
MXPA02003516A (es) 2004-09-10
JP2003511437A (ja) 2003-03-25
PL354137A1 (en) 2003-12-29

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Legal Events

Date Code Title Description
FZDE Discontinued