CA2375841A1 - New bispidine compounds useful in the treatment of cardiac arrhythmias - Google Patents
New bispidine compounds useful in the treatment of cardiac arrhythmias Download PDFInfo
- Publication number
- CA2375841A1 CA2375841A1 CA002375841A CA2375841A CA2375841A1 CA 2375841 A1 CA2375841 A1 CA 2375841A1 CA 002375841 A CA002375841 A CA 002375841A CA 2375841 A CA2375841 A CA 2375841A CA 2375841 A1 CA2375841 A1 CA 2375841A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- compound
- alkyl
- compounds
- diazabicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902268-3 | 1999-06-16 | ||
| SE9902268A SE9902268D0 (sv) | 1999-06-16 | 1999-06-16 | Pharmaceutically active compounds |
| PCT/SE2000/001254 WO2000077000A1 (en) | 1999-06-16 | 2000-06-15 | New bispidine compounds useful in the treatment of cardiac arrhythmias |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2375841A1 true CA2375841A1 (en) | 2000-12-21 |
Family
ID=20416100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002375841A Abandoned CA2375841A1 (en) | 1999-06-16 | 2000-06-15 | New bispidine compounds useful in the treatment of cardiac arrhythmias |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1192157A1 (hu) |
| JP (1) | JP2003502329A (hu) |
| KR (1) | KR20020010713A (hu) |
| CN (1) | CN1144805C (hu) |
| AR (1) | AR024577A1 (hu) |
| AU (1) | AU761576B2 (hu) |
| BR (1) | BR0011660A (hu) |
| CA (1) | CA2375841A1 (hu) |
| CZ (1) | CZ20014495A3 (hu) |
| EE (1) | EE200100675A (hu) |
| HK (1) | HK1045520A1 (hu) |
| HU (1) | HUP0203959A3 (hu) |
| IL (1) | IL146754A0 (hu) |
| IS (1) | IS6201A (hu) |
| MX (1) | MXPA01012919A (hu) |
| NO (1) | NO20016117L (hu) |
| NZ (1) | NZ516013A (hu) |
| PL (1) | PL354032A1 (hu) |
| RU (1) | RU2250903C2 (hu) |
| SE (1) | SE9902268D0 (hu) |
| SK (1) | SK18272001A3 (hu) |
| TR (1) | TR200103663T2 (hu) |
| WO (1) | WO2000077000A1 (hu) |
| ZA (1) | ZA200109796B (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR030302A1 (es) * | 2000-07-07 | 2003-08-20 | Astrazeneca Ab | Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios |
| SE0101327D0 (sv) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New crystalline forms |
| TWI499418B (zh) * | 2009-05-21 | 2015-09-11 | Nerviano Medical Sciences Srl | 異喹啉－１（２ｈ）－酮衍生物 |
| DK2729444T3 (en) * | 2011-07-08 | 2017-12-04 | Bayer Ip Gmbh | METHOD FOR PREPARING 2-AMINO-5-CYANO-N, 3-DIMETHYLBENZAMIDE |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT88381B (pt) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos |
| DE3732094A1 (de) * | 1987-09-24 | 1989-04-06 | Basf Ag | Bispidinderivate als klasse iii-antiarrhythmika |
| US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
| US5468858A (en) * | 1993-10-28 | 1995-11-21 | The Board Of Regents Of Oklahoma State University Physical Sciences | N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents |
| SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
-
1999
- 1999-06-16 SE SE9902268A patent/SE9902268D0/xx unknown
-
2000
- 2000-06-15 WO PCT/SE2000/001254 patent/WO2000077000A1/en not_active Application Discontinuation
- 2000-06-15 CA CA002375841A patent/CA2375841A1/en not_active Abandoned
- 2000-06-15 TR TR2001/03663T patent/TR200103663T2/xx unknown
- 2000-06-15 IL IL14675400A patent/IL146754A0/xx unknown
- 2000-06-15 SK SK1827-2001A patent/SK18272001A3/sk unknown
- 2000-06-15 CZ CZ20014495A patent/CZ20014495A3/cs unknown
- 2000-06-15 CN CNB008116962A patent/CN1144805C/zh not_active Expired - Fee Related
- 2000-06-15 NZ NZ516013A patent/NZ516013A/xx unknown
- 2000-06-15 BR BR0011660-2A patent/BR0011660A/pt not_active IP Right Cessation
- 2000-06-15 HU HU0203959A patent/HUP0203959A3/hu unknown
- 2000-06-15 AU AU60324/00A patent/AU761576B2/en not_active Ceased
- 2000-06-15 KR KR1020017016168A patent/KR20020010713A/ko not_active Application Discontinuation
- 2000-06-15 MX MXPA01012919A patent/MXPA01012919A/es unknown
- 2000-06-15 PL PL00354032A patent/PL354032A1/xx not_active Application Discontinuation
- 2000-06-15 RU RU2001132563/04A patent/RU2250903C2/ru not_active IP Right Cessation
- 2000-06-15 EP EP00946589A patent/EP1192157A1/en not_active Withdrawn
- 2000-06-15 JP JP2001503858A patent/JP2003502329A/ja active Pending
- 2000-06-15 EE EEP200100675A patent/EE200100675A/xx unknown
- 2000-06-16 AR ARP000103015A patent/AR024577A1/es not_active Application Discontinuation
-
2001
- 2001-11-28 ZA ZA200109796A patent/ZA200109796B/en unknown
- 2001-12-14 IS IS6201A patent/IS6201A/is unknown
- 2001-12-14 NO NO20016117A patent/NO20016117L/no not_active Application Discontinuation
-
2002
- 2002-09-27 HK HK02107165.2A patent/HK1045520A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK18272001A3 (sk) | 2002-12-03 |
| JP2003502329A (ja) | 2003-01-21 |
| AU6032400A (en) | 2001-01-02 |
| SE9902268D0 (sv) | 1999-06-16 |
| IS6201A (is) | 2001-12-14 |
| EE200100675A (et) | 2003-02-17 |
| CN1144805C (zh) | 2004-04-07 |
| CN1370167A (zh) | 2002-09-18 |
| HUP0203959A3 (en) | 2003-04-28 |
| HK1045520A1 (zh) | 2002-11-29 |
| CZ20014495A3 (cs) | 2002-05-15 |
| MXPA01012919A (es) | 2002-07-30 |
| HUP0203959A2 (hu) | 2003-03-28 |
| NO20016117D0 (no) | 2001-12-14 |
| NO20016117L (no) | 2002-02-15 |
| EP1192157A1 (en) | 2002-04-03 |
| AU761576B2 (en) | 2003-06-05 |
| ZA200109796B (en) | 2003-02-28 |
| NZ516013A (en) | 2003-06-30 |
| PL354032A1 (en) | 2003-12-15 |
| KR20020010713A (ko) | 2002-02-04 |
| WO2000077000A9 (en) | 2003-06-19 |
| IL146754A0 (en) | 2002-07-25 |
| TR200103663T2 (tr) | 2002-05-21 |
| RU2250903C2 (ru) | 2005-04-27 |
| BR0011660A (pt) | 2002-03-26 |
| WO2000077000A1 (en) | 2000-12-21 |
| AR024577A1 (es) | 2002-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1047695B1 (en) | Novel bispidine antiarrhythmic compounds | |
| EP2265611A1 (en) | Tricyclic derivatives as inhibitors of poly(adp-ribose)polymerase (parp) | |
| CA2375841A1 (en) | New bispidine compounds useful in the treatment of cardiac arrhythmias | |
| US7012074B2 (en) | 3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias | |
| US20040229900A1 (en) | Bispidine compounds useful in the treatment of cardiac arrythmias | |
| EP1192154B1 (en) | Bispidine compounds useful in the treatment of cardiac arrhythmias | |
| WO2002004446A1 (en) | New bispidine compounds and their use in the treatment of cardiac arrhythmias | |
| EP1192156B1 (en) | Bispidine compounds useful in the treatment of cardiac arrhythmias | |
| US20030212095A1 (en) | New bispidine compounds and their use in the treatment of cardiac arrhythmias | |
| US20050004113A1 (en) | New bispidine compounds useful in the treatment of cardiac arrhythmias | |
| CZ20002222A3 (cs) | Nové bispidinové sloučeniny s antiarytmickým účinkem |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |