CA2375841A1 - Nouveaux composes de bispidine utiles dans le traitement des arythmies cardiaques - Google Patents
Nouveaux composes de bispidine utiles dans le traitement des arythmies cardiaques Download PDFInfo
- Publication number
- CA2375841A1 CA2375841A1 CA002375841A CA2375841A CA2375841A1 CA 2375841 A1 CA2375841 A1 CA 2375841A1 CA 002375841 A CA002375841 A CA 002375841A CA 2375841 A CA2375841 A CA 2375841A CA 2375841 A1 CA2375841 A1 CA 2375841A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- compound
- alkyl
- compounds
- diazabicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
On décrit des composés de formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?41¿, R?42¿, R?43¿, R?44¿, R?45¿, R?46¿, A et B sont tels que définis dans le descriptif. Ces composés sont utiles pour la prophylaxie et le traitement des arythmies, plus particulièrement des arythmies atriale et ventriculaire.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9902268A SE9902268D0 (sv) | 1999-06-16 | 1999-06-16 | Pharmaceutically active compounds |
SE9902268-3 | 1999-06-16 | ||
PCT/SE2000/001254 WO2000077000A1 (fr) | 1999-06-16 | 2000-06-15 | Nouveaux composes de bispidine utiles dans le traitement des arythmies cardiaques |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2375841A1 true CA2375841A1 (fr) | 2000-12-21 |
Family
ID=20416100
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002375841A Abandoned CA2375841A1 (fr) | 1999-06-16 | 2000-06-15 | Nouveaux composes de bispidine utiles dans le traitement des arythmies cardiaques |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1192157A1 (fr) |
JP (1) | JP2003502329A (fr) |
KR (1) | KR20020010713A (fr) |
CN (1) | CN1144805C (fr) |
AR (1) | AR024577A1 (fr) |
AU (1) | AU761576B2 (fr) |
BR (1) | BR0011660A (fr) |
CA (1) | CA2375841A1 (fr) |
CZ (1) | CZ20014495A3 (fr) |
EE (1) | EE200100675A (fr) |
HK (1) | HK1045520A1 (fr) |
HU (1) | HUP0203959A3 (fr) |
IL (1) | IL146754A0 (fr) |
IS (1) | IS6201A (fr) |
MX (1) | MXPA01012919A (fr) |
NO (1) | NO20016117L (fr) |
NZ (1) | NZ516013A (fr) |
PL (1) | PL354032A1 (fr) |
RU (1) | RU2250903C2 (fr) |
SE (1) | SE9902268D0 (fr) |
SK (1) | SK18272001A3 (fr) |
TR (1) | TR200103663T2 (fr) |
WO (1) | WO2000077000A1 (fr) |
ZA (1) | ZA200109796B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR030302A1 (es) * | 2000-07-07 | 2003-08-20 | Astrazeneca Ab | Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios |
SE0101327D0 (sv) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New crystalline forms |
TWI499418B (zh) * | 2009-05-21 | 2015-09-11 | Nerviano Medical Sciences Srl | 異喹啉-1(2h)-酮衍生物 |
DK2729444T3 (en) * | 2011-07-08 | 2017-12-04 | Bayer Ip Gmbh | METHOD FOR PREPARING 2-AMINO-5-CYANO-N, 3-DIMETHYLBENZAMIDE |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT88381B (pt) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos |
DE3732094A1 (de) * | 1987-09-24 | 1989-04-06 | Basf Ag | Bispidinderivate als klasse iii-antiarrhythmika |
US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
US5468858A (en) * | 1993-10-28 | 1995-11-21 | The Board Of Regents Of Oklahoma State University Physical Sciences | N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents |
SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
-
1999
- 1999-06-16 SE SE9902268A patent/SE9902268D0/xx unknown
-
2000
- 2000-06-15 CN CNB008116962A patent/CN1144805C/zh not_active Expired - Fee Related
- 2000-06-15 IL IL14675400A patent/IL146754A0/xx unknown
- 2000-06-15 SK SK1827-2001A patent/SK18272001A3/sk unknown
- 2000-06-15 KR KR1020017016168A patent/KR20020010713A/ko not_active Application Discontinuation
- 2000-06-15 JP JP2001503858A patent/JP2003502329A/ja active Pending
- 2000-06-15 AU AU60324/00A patent/AU761576B2/en not_active Ceased
- 2000-06-15 BR BR0011660-2A patent/BR0011660A/pt not_active IP Right Cessation
- 2000-06-15 PL PL00354032A patent/PL354032A1/xx not_active Application Discontinuation
- 2000-06-15 MX MXPA01012919A patent/MXPA01012919A/es unknown
- 2000-06-15 EP EP00946589A patent/EP1192157A1/fr not_active Withdrawn
- 2000-06-15 EE EEP200100675A patent/EE200100675A/xx unknown
- 2000-06-15 TR TR2001/03663T patent/TR200103663T2/xx unknown
- 2000-06-15 CZ CZ20014495A patent/CZ20014495A3/cs unknown
- 2000-06-15 NZ NZ516013A patent/NZ516013A/xx unknown
- 2000-06-15 RU RU2001132563/04A patent/RU2250903C2/ru not_active IP Right Cessation
- 2000-06-15 HU HU0203959A patent/HUP0203959A3/hu unknown
- 2000-06-15 CA CA002375841A patent/CA2375841A1/fr not_active Abandoned
- 2000-06-15 WO PCT/SE2000/001254 patent/WO2000077000A1/fr not_active Application Discontinuation
- 2000-06-16 AR ARP000103015A patent/AR024577A1/es not_active Application Discontinuation
-
2001
- 2001-11-28 ZA ZA200109796A patent/ZA200109796B/en unknown
- 2001-12-14 IS IS6201A patent/IS6201A/is unknown
- 2001-12-14 NO NO20016117A patent/NO20016117L/no not_active Application Discontinuation
-
2002
- 2002-09-27 HK HK02107165.2A patent/HK1045520A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AU6032400A (en) | 2001-01-02 |
KR20020010713A (ko) | 2002-02-04 |
WO2000077000A1 (fr) | 2000-12-21 |
CZ20014495A3 (cs) | 2002-05-15 |
RU2250903C2 (ru) | 2005-04-27 |
CN1370167A (zh) | 2002-09-18 |
JP2003502329A (ja) | 2003-01-21 |
EE200100675A (et) | 2003-02-17 |
SE9902268D0 (sv) | 1999-06-16 |
IL146754A0 (en) | 2002-07-25 |
HUP0203959A2 (hu) | 2003-03-28 |
MXPA01012919A (es) | 2002-07-30 |
BR0011660A (pt) | 2002-03-26 |
SK18272001A3 (sk) | 2002-12-03 |
NO20016117L (no) | 2002-02-15 |
ZA200109796B (en) | 2003-02-28 |
WO2000077000A9 (fr) | 2003-06-19 |
HUP0203959A3 (en) | 2003-04-28 |
AU761576B2 (en) | 2003-06-05 |
EP1192157A1 (fr) | 2002-04-03 |
IS6201A (is) | 2001-12-14 |
HK1045520A1 (zh) | 2002-11-29 |
NZ516013A (en) | 2003-06-30 |
AR024577A1 (es) | 2002-10-16 |
NO20016117D0 (no) | 2001-12-14 |
TR200103663T2 (tr) | 2002-05-21 |
PL354032A1 (en) | 2003-12-15 |
CN1144805C (zh) | 2004-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |