CA2370387A1 - Genetic sequence which codes for the flavon synthase ii enzyme and use of the same - Google Patents

Genetic sequence which codes for the flavon synthase ii enzyme and use of the same Download PDF

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Publication number
CA2370387A1
CA2370387A1 CA002370387A CA2370387A CA2370387A1 CA 2370387 A1 CA2370387 A1 CA 2370387A1 CA 002370387 A CA002370387 A CA 002370387A CA 2370387 A CA2370387 A CA 2370387A CA 2370387 A1 CA2370387 A1 CA 2370387A1
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CA
Canada
Prior art keywords
nucleic acid
acid sequence
hybrids
fns
plant
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002370387A
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English (en)
French (fr)
Inventor
Stefan Martens
Gert Forkmann
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Individual
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Individual
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Publication of CA2370387A1 publication Critical patent/CA2370387A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042NADPH-cytochrome P450 reductase (1.6.2.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/825Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
CA002370387A 1999-04-22 2000-04-14 Genetic sequence which codes for the flavon synthase ii enzyme and use of the same Abandoned CA2370387A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19918365.1 1999-04-22
DE19918365A DE19918365A1 (de) 1999-04-22 1999-04-22 Genetische Sequenz, die für Flavonsynthase II Enzyme kodiert, und deren Verwendung
PCT/DE2000/001214 WO2000065073A2 (de) 1999-04-22 2000-04-14 Genetische sequenz, die für flavonsynthase ii enzyme kodiert, und deren verwendung

Publications (1)

Publication Number Publication Date
CA2370387A1 true CA2370387A1 (en) 2000-11-02

Family

ID=7905553

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002370387A Abandoned CA2370387A1 (en) 1999-04-22 2000-04-14 Genetic sequence which codes for the flavon synthase ii enzyme and use of the same

Country Status (6)

Country Link
EP (1) EP1190077A2 (de)
JP (1) JP2002542789A (de)
AU (1) AU5207200A (de)
CA (1) CA2370387A1 (de)
DE (1) DE19918365A1 (de)
WO (1) WO2000065073A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119252B2 (en) 1999-01-29 2006-10-10 Suntory Limited DNAs coding for flavone synthesis, methods of using flavone synthase DNAS, and plants, flowers, and vectors containing flavone synthase DNAs

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005201464C1 (en) * 1999-01-29 2008-12-11 Suntory Holdings Limited Gene encoding flavone synthase
AU2002302551A1 (en) * 2001-04-20 2002-11-05 Technische Universitat Munchen Flavone synthase i enzymes and the use thereof
CA2573490A1 (en) * 2004-07-10 2006-01-26 The Research Foundation Of State University Of New York Production of flavonoids by recombinant microorganisms
CN100422336C (zh) * 2005-06-28 2008-10-01 北京林业大学 根癌农杆菌介导的地被菊花的转基因方法
USPP21595P3 (en) * 2008-12-19 2010-12-28 International Flower Developments Pty Ltd. Dianthus plant named ‘Floriagate’
US20150020242A1 (en) * 2012-02-24 2015-01-15 Suntory Holdings Limited Torenia-originated promoter capable of acting in petals
CN114107071A (zh) * 2021-12-14 2022-03-01 山西省农业科学院园艺研究所 一种仙客来枯萎病病原菌的分离、纯化方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60199817A (ja) * 1984-03-23 1985-10-09 Rikagaku Kenkyusho 制癌剤
JPS62215581A (ja) * 1986-03-18 1987-09-22 Koichi Shiyudo フラボンカルボン酸誘導体
US5126129A (en) * 1988-05-23 1992-06-30 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Cancer therapy using interleukin-2 and flavone compounds
CA2130800C (en) * 1992-03-02 2002-05-14 Yasuhiro Kikuchi Plant genes encoding flavonoid-3',5'-hydroxylase
US5336685A (en) * 1993-04-12 1994-08-09 Sloan-Kettering Institute For Cancer Research Use of flavonoids to treat multidrug resistant cancer cells
JPH0725761A (ja) * 1993-07-09 1995-01-27 Kureha Chem Ind Co Ltd 軟骨保護剤
JPH08104628A (ja) * 1994-10-04 1996-04-23 Sumitomo Pharmaceut Co Ltd マトリックスメタロプロテアーゼ阻害剤
JP3798043B2 (ja) * 1995-07-12 2006-07-19 大鵬薬品工業株式会社 2−チオフラボン誘導体及びその製造方法
JPH09224671A (ja) * 1996-02-19 1997-09-02 Mitsui Gyosai Shokubutsu Bio Kenkyusho:Kk 新規なチトクロームp450をコードするdna
AUPN838696A0 (en) * 1996-03-01 1996-03-21 Florigene Limited Genetic sequences encoding flavonoid pathway enzymes and uses therefor
JPH09301915A (ja) * 1996-05-08 1997-11-25 Sankyo Co Ltd フラボン及びナフタレン誘導体
JP4368005B2 (ja) * 1999-01-29 2009-11-18 インターナショナル フラワー ディベロプメンツ プロプライアタリー リミティド フラボン合成酵素をコードする遺伝子

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119252B2 (en) 1999-01-29 2006-10-10 Suntory Limited DNAs coding for flavone synthesis, methods of using flavone synthase DNAS, and plants, flowers, and vectors containing flavone synthase DNAs
US7422881B2 (en) 1999-01-29 2008-09-09 International Flower Developments Proprietary Limited DNAs coding for flavone synthases, methods of using flavone synthase DNAs, and plants, flowers, and vectors containing flavone synthase DNAs
US7465569B2 (en) 1999-01-29 2008-12-16 International Flower Developments Proprietary Limited Flavone synthases, methods of using flavone synthases, and plants expressing flavone synthases
US7507566B2 (en) 1999-01-29 2009-03-24 International Flower Developments Proprietary Limited Flavone synthases, methods of using flavone synthases, and plants expressing flavone synthases

Also Published As

Publication number Publication date
DE19918365A1 (de) 2000-10-26
EP1190077A2 (de) 2002-03-27
JP2002542789A (ja) 2002-12-17
WO2000065073A3 (de) 2001-04-19
AU5207200A (en) 2000-11-10
WO2000065073A2 (de) 2000-11-02

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