CA2359242C - Growth differentiation factor inhibitors and uses therefor - Google Patents
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- CA2359242C CA2359242C CA002359242A CA2359242A CA2359242C CA 2359242 C CA2359242 C CA 2359242C CA 002359242 A CA002359242 A CA 002359242A CA 2359242 A CA2359242 A CA 2359242A CA 2359242 C CA2359242 C CA 2359242C
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| US11663999P | 1999-01-21 | 1999-01-21 | |
| US60/116,639 | 1999-01-21 | ||
| US13836399P | 1999-06-10 | 1999-06-10 | |
| US60/138,363 | 1999-06-10 | ||
| PCT/US2000/001552 WO2000043781A2 (en) | 1999-01-21 | 2000-01-21 | Growth differentiation factor inhibitors and uses therefor |
Publications (2)
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| CA2359242A1 CA2359242A1 (en) | 2000-07-27 |
| CA2359242C true CA2359242C (en) | 2009-12-08 |
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| CA002359242A Expired - Fee Related CA2359242C (en) | 1999-01-21 | 2000-01-21 | Growth differentiation factor inhibitors and uses therefor |
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| CN (1) | CN100567322C (https=) |
| AT (1) | ATE322681T1 (https=) |
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| BR (1) | BR0008188A (https=) |
| CA (1) | CA2359242C (https=) |
| DE (1) | DE60027135T2 (https=) |
| HK (1) | HK1041521B (https=) |
| MX (1) | MXPA01007366A (https=) |
| NZ (1) | NZ513642A (https=) |
| WO (1) | WO2000043781A2 (https=) |
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| US7393682B1 (en) * | 1993-03-19 | 2008-07-01 | The Johns Hopkins University School Of Medicine | Polynucleotides encoding promyostatin polypeptides |
| DE69434651T2 (de) | 1993-12-07 | 2007-03-08 | Genetics Institute, Inc., Cambridge | Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen |
| US6891082B2 (en) * | 1997-08-01 | 2005-05-10 | The Johns Hopkins University School Of Medicine | Transgenic non-human animals expressing a truncated activintype II receptor |
| US6656475B1 (en) * | 1997-08-01 | 2003-12-02 | The Johns Hopkins University School Of Medicine | Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same |
| US7037501B2 (en) | 2001-01-04 | 2006-05-02 | Regents Of The University Of Minnesota | Myostatin immnoconjugate |
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| EP1790726B1 (en) * | 2001-02-08 | 2013-07-03 | Wyeth LLC | Modified and stabilized GDF propeptides and uses thereof |
| US6734289B2 (en) | 2001-03-29 | 2004-05-11 | The University Of Chicago | Gastrokines and derived peptides including inhibitors |
| US7629317B2 (en) | 2001-03-29 | 2009-12-08 | The University Of Chicago | Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors |
| DE60213248T2 (de) * | 2001-06-05 | 2006-11-30 | Genetics Institute, LLC, Cambridge | Verfahren zur reinigung hochanionischer proteine |
| CA2453189A1 (en) * | 2001-07-11 | 2003-01-23 | Ovita Limited | Bioassay for myostatin |
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| CA2476887A1 (en) | 2002-02-21 | 2003-09-04 | Wyeth | Gasp1:a follistatin domain containing protein |
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| US8017576B2 (en) | 2005-05-10 | 2011-09-13 | The University Of Chicago | Methods and compositions to treat mucositis |
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| UA92504C2 (en) | 2005-10-12 | 2010-11-10 | Эли Лилли Энд Компани | Anti-myostatin monoclonal antibody |
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| WO2017177013A1 (en) | 2016-04-06 | 2017-10-12 | Acceleron Pharma Inc. | Alk7 antagonists and uses thereof |
| HRP20210694T1 (hr) | 2016-07-15 | 2021-09-17 | Acceleron Pharma, Inc. | Pripravci koji sadrže actriia polipeptide za uporabu za liječenje plućne hipertenzije |
| PL3490582T3 (pl) | 2016-07-27 | 2024-09-23 | Acceleron Pharma Inc. | Kompozycje do zastosowania w leczeniu mielofibrozy |
| BR112019006993A2 (pt) | 2016-10-05 | 2019-09-03 | Acceleron Pharma Inc | heteromultímeros de alk4:actriib e usos dos mesmos |
| JP7280182B2 (ja) | 2016-10-05 | 2023-05-23 | アクセルロン ファーマ インコーポレイテッド | バリアントＡｃｔＲＩＩＢタンパク質およびその使用 |
| JP2019529509A (ja) | 2016-10-05 | 2019-10-17 | アクセレロン ファーマ インコーポレーテッド | 腎臓疾患を治療するための組成物および方法 |
| JOP20190085A1 (ar) | 2016-10-20 | 2019-04-17 | Biogen Ma Inc | طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة |
| CA3124415A1 (en) | 2018-12-21 | 2020-06-25 | Northwestern University | Use of annexins in preventing and treating muscle membrane injury |
| US20220062299A1 (en) | 2018-12-26 | 2022-03-03 | Northwestern University | Use of glucocorticoid steroids in preventing and treating conditions of muscle wasting, aging and metabolic disorder |
| EP3995153A4 (en) * | 2019-06-26 | 2023-11-22 | KNC Laboratories Co., Ltd. | Nucleic acid drug suppressing production of myostatin gene mrna |
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| US5254678A (en) * | 1987-12-15 | 1993-10-19 | Gene Shears Pty. Limited | Ribozymes |
| DK0690873T3 (da) * | 1993-03-19 | 2003-09-29 | Univ Johns Hopkins Med | Vækstdifferentieringsfaktor-8 |
| US5616466A (en) * | 1993-11-05 | 1997-04-01 | Cantor; Glenn H. | Ribozyme-mediated inhibition of bovine leukemia virus |
| CA2194660C (en) * | 1994-07-08 | 2009-09-29 | Se-Jin Lee | Growth differentiation factor-11 |
| US6008434A (en) * | 1994-07-08 | 1999-12-28 | Johns Hopkins University School Of Medicine | Growth differentiation factor-11 transgenic mice |
| US5674748A (en) * | 1995-03-14 | 1997-10-07 | Thomas Jefferson University | Human cyclin-dependent kinase-like proteins and methods of using the same |
| US6124115A (en) * | 1995-09-22 | 2000-09-26 | Endorecherche Inc. | Production and use of isolated type 5 17β-hydroxysteroid dehydrogenase |
| US5824519A (en) * | 1995-11-08 | 1998-10-20 | Medical University Of South Carolina | Tissue-specific and target RNA-specific ribozymes |
| WO1998024925A1 (en) * | 1995-11-08 | 1998-06-11 | Medical University Of South Carolina | Tissue specific and target rna-specific ribozymes as antimicrobial therapeutics against microbial pathogens |
| WO1998033887A1 (en) * | 1997-02-05 | 1998-08-06 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-8 |
| NO971997D0 (no) * | 1997-04-29 | 1997-04-29 | Kjetil Tasken | Bruk av immunmodulerende midler |
| DE69841139D1 (de) * | 1997-07-14 | 2009-10-22 | Univ Liege | Mutationen im myostatingen steigern muskelmasse in säugetieren |
| AU8666398A (en) * | 1997-08-01 | 1999-02-22 | Johns Hopkins University School Of Medicine, The | Methods to identify growth differentiation factor (gdf) receptors |
| US6369201B1 (en) * | 1998-02-19 | 2002-04-09 | Metamorphix International, Inc. | Myostatin multimers |
| AU765832B2 (en) * | 1998-07-28 | 2003-10-02 | Johns Hopkins University School Of Medicine, The | Growth differentiation factor-11 |
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2000
- 2000-01-21 AU AU25140/00A patent/AU772694B2/en not_active Ceased
- 2000-01-21 BR BR0008188-4A patent/BR0008188A/pt not_active Application Discontinuation
- 2000-01-21 HK HK02103086.7A patent/HK1041521B/en not_active IP Right Cessation
- 2000-01-21 NZ NZ513642A patent/NZ513642A/en not_active IP Right Cessation
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- 2000-01-21 DE DE60027135T patent/DE60027135T2/de not_active Expired - Lifetime
- 2000-01-21 CN CNB008053782A patent/CN100567322C/zh not_active Expired - Fee Related
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- 2000-01-21 JP JP2000595151A patent/JP2003517580A/ja active Pending
- 2000-01-21 AT AT00903387T patent/ATE322681T1/de not_active IP Right Cessation
- 2000-01-21 CA CA002359242A patent/CA2359242C/en not_active Expired - Fee Related
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2004
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| AU2004203398A1 (en) | 2004-08-19 |
| BR0008188A (pt) | 2002-02-13 |
| MXPA01007366A (es) | 2002-06-04 |
| EP1147413A2 (en) | 2001-10-24 |
| WO2000043781A2 (en) | 2000-07-27 |
| WO2000043781A3 (en) | 2001-02-01 |
| CN1355881A (zh) | 2002-06-26 |
| JP2003517580A (ja) | 2003-05-27 |
| DE60027135T2 (de) | 2007-01-11 |
| ATE322681T1 (de) | 2006-04-15 |
| AU2514000A (en) | 2000-08-07 |
| DE60027135D1 (de) | 2006-05-18 |
| CA2359242A1 (en) | 2000-07-27 |
| EP1147413B1 (en) | 2006-04-05 |
| HK1041521A1 (en) | 2002-07-12 |
| HK1041521B (en) | 2006-11-17 |
| CN100567322C (zh) | 2009-12-09 |
| AU772694B2 (en) | 2004-05-06 |
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