AR050187A1 - Uso de inhibidores de alk 5 para modular o inhibir la actividad de miostatina, a fin de lograr mayor acumulacion de tejido magro en animales - Google Patents
Uso de inhibidores de alk 5 para modular o inhibir la actividad de miostatina, a fin de lograr mayor acumulacion de tejido magro en animalesInfo
- Publication number
- AR050187A1 AR050187A1 ARP050103119A ARP050103119A AR050187A1 AR 050187 A1 AR050187 A1 AR 050187A1 AR P050103119 A ARP050103119 A AR P050103119A AR P050103119 A ARP050103119 A AR P050103119A AR 050187 A1 AR050187 A1 AR 050187A1
- Authority
- AR
- Argentina
- Prior art keywords
- animals
- miostatine
- magro
- alk
- modulate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
Abstract
Métodos para aumentar el tejido muscular en animales. En un aspecto el método comprende la administracion de una cantidad eficaz de un inhibidor del receptor ALK5, tal como se muestra en formula (1), a un animal, durante un tiempo suficiente para povocar el efecto deseado. Una alimentacion para ganado y un equipo para aumentar el deposito de musculo en animales. Un método para la produccion de carne y un método para disminuir el tejido graso en animales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59235904P | 2004-07-29 | 2004-07-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR050187A1 true AR050187A1 (es) | 2006-10-04 |
Family
ID=35595039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050103119A AR050187A1 (es) | 2004-07-29 | 2005-07-27 | Uso de inhibidores de alk 5 para modular o inhibir la actividad de miostatina, a fin de lograr mayor acumulacion de tejido magro en animales |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060194845A1 (es) |
EP (1) | EP1771171A1 (es) |
JP (1) | JP2008506787A (es) |
CN (1) | CN101031294A (es) |
AR (1) | AR050187A1 (es) |
AU (1) | AU2005280496B2 (es) |
BR (1) | BRPI0513914A (es) |
CA (1) | CA2576734C (es) |
MX (1) | MX2007001118A (es) |
NO (1) | NO20071113L (es) |
PE (1) | PE20060729A1 (es) |
TW (1) | TW200616621A (es) |
WO (1) | WO2006025988A1 (es) |
ZA (1) | ZA200700681B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008071605A2 (en) * | 2006-12-15 | 2008-06-19 | F. Hoffmann-La Roche Ag | Methods of treating inflammatory diseases |
US20100144865A1 (en) * | 2007-05-04 | 2010-06-10 | Jana Pickova | Compound feed for aquaculture |
GB0715087D0 (en) | 2007-08-03 | 2007-09-12 | Summit Corp Plc | Drug combinations for the treatment of duchenne muscular dystrophy |
PL2170396T3 (pl) | 2007-08-03 | 2017-07-31 | Summit (Oxford) Limited | Kombinacje leków do leczenia dystrofii mięśniowej Duchenne'a |
WO2009047163A1 (en) * | 2007-10-10 | 2009-04-16 | F. Hoffmann-La Roche Ag | Methods of treating inflammatory diseases |
CN101684457B (zh) * | 2009-07-27 | 2013-01-09 | 中国科学院广州生物医药与健康研究院 | I型转化生长因子受体抑制剂在产生诱导多能干细胞中的应用及其方法 |
CA2831827A1 (en) * | 2011-04-05 | 2012-10-11 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Compounds and methods for altering activin receptor-like kinase signalling |
WO2013137832A1 (en) * | 2012-03-16 | 2013-09-19 | Nanyang Technological University | Myostatin inhibitors |
EP3711771A1 (en) | 2012-08-01 | 2020-09-23 | Ikaika Therapeutics, LLC | Mitigating tissue damage and fibrosis via latent transforming growth factor beta binding protein (ltbp4) |
WO2016025629A1 (en) | 2014-08-12 | 2016-02-18 | The Regents Of The University Of California | Molecular composition for enhancing and rejuvenating maintenance and repair of mammalian tissues |
KR102434226B1 (ko) | 2016-06-30 | 2022-08-19 | 한미약품 주식회사 | Alk5 억제제로서의 신규 피라졸 유도체 및 이의 용도 |
JP2022511112A (ja) | 2018-12-11 | 2022-01-28 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | Alk5阻害剤としてのナフチリジンおよびキノリン誘導体 |
AU2019406214A1 (en) | 2018-12-21 | 2021-08-05 | Northwestern University | Use of annexins in preventing and treating muscle membrane injury |
US20220062299A1 (en) | 2018-12-26 | 2022-03-03 | Northwestern University | Use of glucocorticoid steroids in preventing and treating conditions of muscle wasting, aging and metabolic disorder |
AU2020385400A1 (en) | 2019-11-22 | 2022-06-09 | Theravance Biopharma R&D Ip, Llc | Substituted 1,5-naphthyridines or quinolines as ALK5 inhibitors |
WO2022104071A2 (en) * | 2020-11-13 | 2022-05-19 | The Jackson Laboratory | Therapeutics targeting transforming growth factor beta family signaling |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6656475B1 (en) * | 1997-08-01 | 2003-12-02 | The Johns Hopkins University School Of Medicine | Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same |
EP1147413B1 (en) * | 1999-01-21 | 2006-04-05 | Metamorphix, Inc. | Growth differentiation factor inhibitors and uses therefor |
ES2187473T3 (es) * | 1999-04-09 | 2003-06-16 | Smithkline Beecham Corp | Triarylimidazoles. |
GB0007405D0 (en) * | 2000-03-27 | 2000-05-17 | Smithkline Beecham Corp | Compounds |
-
2005
- 2005-07-27 EP EP05810799A patent/EP1771171A1/en not_active Withdrawn
- 2005-07-27 US US11/190,453 patent/US20060194845A1/en not_active Abandoned
- 2005-07-27 AR ARP050103119A patent/AR050187A1/es not_active Application Discontinuation
- 2005-07-27 CN CNA2005800331272A patent/CN101031294A/zh active Pending
- 2005-07-27 PE PE2005000882A patent/PE20060729A1/es not_active Application Discontinuation
- 2005-07-27 BR BRPI0513914-7A patent/BRPI0513914A/pt not_active IP Right Cessation
- 2005-07-27 JP JP2007522848A patent/JP2008506787A/ja active Pending
- 2005-07-27 AU AU2005280496A patent/AU2005280496B2/en not_active Ceased
- 2005-07-27 WO PCT/US2005/026607 patent/WO2006025988A1/en active Application Filing
- 2005-07-27 MX MX2007001118A patent/MX2007001118A/es not_active Application Discontinuation
- 2005-07-27 CA CA2576734A patent/CA2576734C/en not_active Expired - Fee Related
- 2005-07-28 TW TW094125600A patent/TW200616621A/zh unknown
-
2007
- 2007-01-24 ZA ZA200700681A patent/ZA200700681B/en unknown
- 2007-02-27 NO NO20071113A patent/NO20071113L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2005280496B2 (en) | 2009-10-08 |
WO2006025988A1 (en) | 2006-03-09 |
PE20060729A1 (es) | 2006-08-12 |
CN101031294A (zh) | 2007-09-05 |
CA2576734A1 (en) | 2006-03-09 |
NO20071113L (no) | 2007-02-27 |
TW200616621A (en) | 2006-06-01 |
US20060194845A1 (en) | 2006-08-31 |
CA2576734C (en) | 2010-03-16 |
JP2008506787A (ja) | 2008-03-06 |
ZA200700681B (en) | 2008-07-30 |
MX2007001118A (es) | 2007-03-15 |
BRPI0513914A (pt) | 2008-05-20 |
AU2005280496A1 (en) | 2006-03-09 |
EP1771171A1 (en) | 2007-04-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |