CA2353620A1 - Procedes et formulations permettant de reduire des anticorps circulants - Google Patents
Procedes et formulations permettant de reduire des anticorps circulants Download PDFInfo
- Publication number
- CA2353620A1 CA2353620A1 CA002353620A CA2353620A CA2353620A1 CA 2353620 A1 CA2353620 A1 CA 2353620A1 CA 002353620 A CA002353620 A CA 002353620A CA 2353620 A CA2353620 A CA 2353620A CA 2353620 A1 CA2353620 A1 CA 2353620A1
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- Prior art keywords
- agal
- compound
- epitope
- antibodies
- antibody
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention concerne des procédés permettant de réduire la concentration d'anticorps circulant, et notamment des anticorps associés à des maladies. Ces méthodes consistent à administrer à un individu des quantités efficaces de supports présentant des épitopes. Dans d'autres modes de réalisation, l'invention concerne des procédés utilisant des supports présentant des épitopes et permettant de réduire la concentration d'anticorps en circulation.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11163998P | 1998-12-09 | 1998-12-09 | |
US60/111,639 | 1998-12-09 | ||
US45787599A | 1999-12-08 | 1999-12-08 | |
US09/457,875 | 1999-12-08 | ||
PCT/US1999/029336 WO2000033887A2 (fr) | 1998-12-08 | 1999-12-09 | Procedes et formulations permettant de reduire des anticorps circulants |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2353620A1 true CA2353620A1 (fr) | 2000-06-15 |
Family
ID=26809097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002353620A Abandoned CA2353620A1 (fr) | 1998-12-09 | 1999-12-09 | Procedes et formulations permettant de reduire des anticorps circulants |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1135167A2 (fr) |
JP (1) | JP2002531531A (fr) |
AU (1) | AU2173500A (fr) |
CA (1) | CA2353620A1 (fr) |
WO (1) | WO2000033887A2 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001041813A2 (fr) | 1999-11-28 | 2001-06-14 | La Jolla Pharmaceutical Company | Procedes de traitement de lupus sur la base de l'affinite aux anticorps et procedes de criblage et compositions associees |
WO2006115509A2 (fr) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Immuno-potentialisateurs a petites molecules et analyses visant a detecter leur presence |
PL3116887T3 (pl) | 2014-03-13 | 2021-09-06 | Universität Basel | Ligandy węglowodanowe, które wiążą się z przeciwciałami igm przeciwko glikoproteinie związanej z mieliną |
US11091591B2 (en) | 2015-09-16 | 2021-08-17 | Universität Basel | Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids |
EP3715375A1 (fr) | 2019-03-23 | 2020-09-30 | Ablevia biotech GmbH | Composé pour la prévention ou le traitement de la pré-éclampsie |
EP3715374A1 (fr) | 2019-03-23 | 2020-09-30 | Ablevia biotech GmbH | Composé de séquestration d'anticorps indésirables chez un patient |
US11986536B2 (en) | 2019-03-23 | 2024-05-21 | Ablevia Biotech Gmbh | Compound for the sequestration of undesirable antibodies in a patient |
EP3715376A1 (fr) | 2019-03-23 | 2020-09-30 | Ablevia biotech GmbH | Composé pour la prévention ou le traitement de la myasthénie grave |
AU2021347583A1 (en) | 2020-09-23 | 2023-05-25 | Ablevia Biotech Gmbh | Compound for increasing efficacy of viral vectors |
MX2023003375A (es) | 2020-09-23 | 2023-03-31 | Ablevia Biotech Gmbh | Compuesto para aumentar la eficacia de la terapia de sustitucion del factor viii. |
EP4216990A1 (fr) | 2020-09-23 | 2023-08-02 | Ablevia biotech GmbH | Composé pour la séquestration d'anticorps indésirables chez un patient |
TW202228784A (zh) | 2020-09-23 | 2022-08-01 | 奧地利商艾柏力維亞生技有限公司 | 用以於一患者中螯合非預期的抗peg抗體的化合物 |
JP2023542389A (ja) | 2020-09-23 | 2023-10-06 | アブレヴィア バイオテック ゲーエムベーハー | 自己抗体で媒介される状態の予防又は治療のための化合物 |
KR20230074552A (ko) | 2020-09-24 | 2023-05-30 | 아블레비아 바이오테크 게엠베하 | 중증 근무력증의 예방 또는 치료용 화합물 |
WO2023180502A1 (fr) | 2022-03-24 | 2023-09-28 | Ablevia Biotech Gmbh | Composé pour augmentation de l'efficacité des virus oncolytiques |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5782792A (en) * | 1986-11-21 | 1998-07-21 | Cypress Bioscience, Inc. | Method for treatment of rheumatoid arthritis |
US5552391A (en) * | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
JP3201523B2 (ja) * | 1991-08-23 | 2001-08-20 | アルバータ リサーチ カウンスル | ヒト受容体における抗体−仲介異種移植拒絶を弱めるための方法および組成物 |
EP0970114B1 (fr) * | 1997-04-18 | 2006-07-12 | Novartis AG | Neoglycoproteines |
WO1999052561A1 (fr) * | 1998-04-15 | 1999-10-21 | Baxter International Inc. | Inhibition d'anticorps xenoreactifs |
-
1999
- 1999-12-09 JP JP2000586377A patent/JP2002531531A/ja not_active Withdrawn
- 1999-12-09 EP EP99966115A patent/EP1135167A2/fr not_active Withdrawn
- 1999-12-09 WO PCT/US1999/029336 patent/WO2000033887A2/fr not_active Application Discontinuation
- 1999-12-09 CA CA002353620A patent/CA2353620A1/fr not_active Abandoned
- 1999-12-09 AU AU21735/00A patent/AU2173500A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000033887A3 (fr) | 2000-08-17 |
AU2173500A (en) | 2000-06-26 |
EP1135167A2 (fr) | 2001-09-26 |
JP2002531531A (ja) | 2002-09-24 |
WO2000033887A2 (fr) | 2000-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |