CA2343113C - Anionic or cationic dendrimer antimicrobial or antiparasitic compositions - Google Patents

Anionic or cationic dendrimer antimicrobial or antiparasitic compositions Download PDF

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Publication number
CA2343113C
CA2343113C CA002343113A CA2343113A CA2343113C CA 2343113 C CA2343113 C CA 2343113C CA 002343113 A CA002343113 A CA 002343113A CA 2343113 A CA2343113 A CA 2343113A CA 2343113 C CA2343113 C CA 2343113C
Authority
CA
Canada
Prior art keywords
terminated dendrimers
acid
dendrimer
solution
pamam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002343113A
Other languages
English (en)
French (fr)
Other versions
CA2343113A1 (en
Inventor
Barry Ross Matthews
George Holan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Starpharma Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Starpharma Pty Ltd filed Critical Starpharma Pty Ltd
Publication of CA2343113A1 publication Critical patent/CA2343113A1/en
Application granted granted Critical
Publication of CA2343113C publication Critical patent/CA2343113C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/16—Dendrimers and dendritic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002343113A 1998-09-14 1999-09-13 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions Expired - Lifetime CA2343113C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP5842A AUPP584298A0 (en) 1998-09-14 1998-09-14 Antimicrobial and antiparasitic agents
AUPP5842 1998-09-14
PCT/AU1999/000763 WO2000015240A1 (en) 1998-09-14 1999-09-13 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions

Publications (2)

Publication Number Publication Date
CA2343113A1 CA2343113A1 (en) 2000-03-23
CA2343113C true CA2343113C (en) 2009-11-24

Family

ID=3810064

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002343113A Expired - Lifetime CA2343113C (en) 1998-09-14 1999-09-13 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions

Country Status (12)

Country Link
US (1) US6464971B1 (https=)
EP (1) EP1113806B1 (https=)
JP (1) JP4979848B2 (https=)
KR (1) KR100720905B1 (https=)
CN (2) CN101352451A (https=)
AT (1) ATE372123T1 (https=)
AU (1) AUPP584298A0 (https=)
BR (1) BR9913712A (https=)
CA (1) CA2343113C (https=)
DE (1) DE69937059T2 (https=)
NZ (1) NZ510289A (https=)
WO (1) WO2000015240A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8962662B2 (en) 2011-11-15 2015-02-24 Byocoat Enterprises, Inc. Antimicrobial compositions and methods of use thereof

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572459B2 (en) * 1998-09-14 2009-08-11 Starpharma Pty Ltd. Anionic or cationic dendrimer antimicrobial or antiparasitic compositions
KR100413532B1 (ko) * 2001-02-14 2003-12-31 학교법인 포항공과대학교 폴리아민이 말단에 치환된 덴드리머 및 그 제조방법
AUPR412901A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agents for the prevention and treatment of sexually transmitted disease s - II
AUPR412801A0 (en) * 2001-03-30 2001-05-03 Starpharma Limited Agent for the prevention and treatment of sexually transmitted disease s - I
WO2003049772A2 (en) * 2001-12-11 2003-06-19 The Board Of Trustees Of The Leland Stanford Junior University Guanidinium transport reagents and conjugates
AU2003256038A1 (en) * 2002-08-30 2004-03-19 Ramot At Tel Aviv University Ltd. Self-immolative dendrimers releasing many active moieties upon a single activating event
US20040234496A1 (en) * 2003-02-06 2004-11-25 Stockel Richard F. Biocidal compositions
US7074459B2 (en) * 2003-05-23 2006-07-11 Stockel Richard F Method for preserving wood
FR2862650B1 (fr) * 2003-11-24 2007-04-20 Rhodia Cons Spec Ltd Nouveaux dendrimeres a terminaisons monophosphoniques, leur procede de preparation et leur utilisation
FR2862651B1 (fr) * 2003-11-24 2006-03-31 Rhodia Cons Spec Ltd Nouveaux dendrimeres a terminaisons bisphosphoniques et derives, leur procede de preparation et leur utilisation
CN1296711C (zh) * 2004-05-14 2007-01-24 沈阳迈迪生物医学技术有限公司 乳腺癌的Her－2免疫组织化学诊断试剂盒
JP4553354B2 (ja) 2004-10-04 2010-09-29 正隆 井原 抗トリパノソーマ剤
US8790672B2 (en) * 2005-02-22 2014-07-29 Nina M. Lamba-Kohli Generation of antimicrobial surfaces using dendrimer biocides
US20060269480A1 (en) * 2005-05-31 2006-11-30 Ramot At Tel Aviv University Ltd. Multi-triggered self-immolative dendritic compounds
WO2007006700A1 (en) * 2005-07-08 2007-01-18 Janssen Pharmaceutica N.V. Modified poly(propylene-imine) dendrimers and their use as transfection agents for anionic bioactive factors
PL1937284T3 (pl) * 2005-10-18 2016-05-31 Starpharma Pty Ltd System podawania kompozycji bakteriobójczego dendymeru
WO2007045010A1 (en) * 2005-10-21 2007-04-26 Starpharma Pty Limited Inhibitory compounds
US8067402B2 (en) * 2005-12-12 2011-11-29 Allaccem, Inc. Methods and systems for coating an oral surface
JP5989294B2 (ja) 2006-01-20 2016-09-07 スターファーマ・プロプライエタリー・リミテッドＳｔａｒｐｈａｒｍａ Ｐｔｙ Ｌｔｄ 修飾高分子
EP1996209B1 (en) * 2006-03-22 2015-11-04 Starpharma Pty Limited Contraceptive composition
CA2683383C (en) 2007-02-21 2016-01-05 Allaccem, Incorporated Bridged polycyclic compound based compositions for the inhibition and amelioration of disease
US20080282480A1 (en) * 2007-05-15 2008-11-20 The Hong Kong Polytechnic University Multifunction Finishing Liquids Containing Dendrimers and the Application of the Liquids in Textile Finishing
WO2009045237A1 (en) * 2007-05-21 2009-04-09 California Institute Of Technology Extraction of actinides from mixtures and ores using dendritic macromolecules
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
US20100008864A1 (en) * 2008-07-10 2010-01-14 Andreas Meijer Aromatic multimers
US9815712B2 (en) 2008-10-03 2017-11-14 California Institute Of Technology High capacity perchlorate-selective resins from hyperbranched macromolecules
WO2010040117A2 (en) * 2008-10-03 2010-04-08 California Institute Of Technology Extraction of anions from solutions and mixtures using hyperbranched macromolecules
US20120101041A1 (en) 2009-07-01 2012-04-26 Japan Science And Technology Agency Polyionic dendrimer and hydrogel comprising same
JP5212656B2 (ja) * 2009-09-02 2013-06-19 日産化学工業株式会社 イソチオシアナト化合物の製造方法
US8658702B2 (en) 2009-12-17 2014-02-25 Mamadou Diallo Soluble anion exchangers from hyperbranched macromolecules
CN103179855B (zh) * 2010-06-30 2015-07-08 刘慧文 抗菌化合物
RU2478106C2 (ru) * 2010-11-25 2013-03-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) СОЕДИНЕНИЯ НА ОСНОВЕ КОМПЛЕКСОВ ГИПЕРРАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ Boltorn H, ОБЛАДАЮЩИЕ АНТИКАНДИДОЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ
US9102602B2 (en) 2010-11-29 2015-08-11 Nissan Chemical Industries, Ltd. Method for producing isothiocyanate compound
KR20180126621A (ko) * 2011-05-16 2018-11-27 스타파마 피티와이 리미티드 세균성 질염의 치료 또는 예방 방법
JP6419701B2 (ja) * 2012-09-13 2018-11-07 スターファーマ・ピーティーワイ・リミテッド 眼の感染症の治療または予防方法
EP2958429A4 (en) * 2013-02-20 2016-10-05 Biolog Inc COMPOSITIONS AND METHODS FOR INACTIVATION AND / OR REDUCTION OF MICROBIAL TOXIN PRODUCTION
ES2835382T3 (es) * 2013-03-15 2021-06-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones de poliamidas antimicrobianas y tratamiento de la mastitis
GB201405660D0 (en) * 2014-03-28 2014-05-14 Gama Healthcare Ltd A liquid disinfecting composition
CN103999853B (zh) * 2014-06-11 2015-07-22 中国农业大学 荧光树枝状纳米大分子在制备药物载体中的应用
US9854806B2 (en) 2015-05-19 2018-01-02 International Business Machines Corporation Antimicrobial guanidinium and thiouronium functionalized polymers
MX379091B (es) * 2016-04-14 2025-03-10 Boehringer Ingelheim Animal Health Usa Inc Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina.
WO2018081861A1 (en) * 2016-11-02 2018-05-11 The University Of Melbourne Antimicrobial composition combinations comprising star shaped peptide polymers
WO2018081845A1 (en) 2016-11-02 2018-05-11 The University Of Melbourne Antibacterial compositions and methods
US10953039B2 (en) 2018-09-27 2021-03-23 International Business Machines Corporation Utilizing polymers and antibiotics to enhance antimicrobial activity and inhibit antibiotic resistance
CN110041523B (zh) * 2019-04-15 2021-04-30 同济大学 低代树枝状聚赖氨酸类抗菌肽及其制备方法
CN114053392B (zh) * 2020-07-30 2024-06-21 广州朗圣药业有限公司 新型化合物在制备预防和/或治疗hpv感染的药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM623994A0 (en) * 1994-06-15 1994-07-07 Biomolecular Research Institute Limited Antiviral dendrimers
US5736533A (en) * 1995-06-07 1998-04-07 Neose Technologies, Inc. Bacterial inhibition with an oligosaccharide compound
US5658574A (en) 1995-10-13 1997-08-19 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cleansing compositions with dendrimers as mildness agents
DE19624705A1 (de) * 1996-06-20 1998-01-08 Deutsches Krebsforsch Dendrimere auf Saccharid-Basis
AUPO104496A0 (en) * 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Angiogenic inhibitory compounds
WO1998026662A1 (en) 1996-12-19 1998-06-25 The Penn State Research Foundation Compounds and methods for treating and preventing bacterial and viral disease
AUPP584398A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Inhibition of toxic materials or substances

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8962662B2 (en) 2011-11-15 2015-02-24 Byocoat Enterprises, Inc. Antimicrobial compositions and methods of use thereof

Also Published As

Publication number Publication date
WO2000015240A1 (en) 2000-03-23
DE69937059D1 (de) 2007-10-18
CA2343113A1 (en) 2000-03-23
AUPP584298A0 (en) 1998-10-08
JP2002524524A (ja) 2002-08-06
JP4979848B2 (ja) 2012-07-18
BR9913712A (pt) 2001-05-29
NZ510289A (en) 2002-10-25
KR20010075066A (ko) 2001-08-09
EP1113806B1 (en) 2007-09-05
EP1113806A1 (en) 2001-07-11
DE69937059T2 (de) 2008-05-29
EP1113806A4 (en) 2003-06-25
ATE372123T1 (de) 2007-09-15
CN101352451A (zh) 2009-01-28
US6464971B1 (en) 2002-10-15
KR100720905B1 (ko) 2007-05-25
CN1323214A (zh) 2001-11-21

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