CA2338885A1 - Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines - Google Patents

Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines Download PDF

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Publication number
CA2338885A1
CA2338885A1 CA002338885A CA2338885A CA2338885A1 CA 2338885 A1 CA2338885 A1 CA 2338885A1 CA 002338885 A CA002338885 A CA 002338885A CA 2338885 A CA2338885 A CA 2338885A CA 2338885 A1 CA2338885 A1 CA 2338885A1
Authority
CA
Canada
Prior art keywords
seq
ranatuerin
rana
peptide
temporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002338885A
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English (en)
Inventor
J. Michael Conlon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
BioNebraska Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioNebraska Inc filed Critical BioNebraska Inc
Publication of CA2338885A1 publication Critical patent/CA2338885A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne sept familles de peptides Rana isolés à partir de la peau de six espèces de grenouilles américaines, ainsi que leurs versions modifiées et tronquées. Ces peptides sont dénommés peptides Rana et possèdent une activité antibactérienne.
CA002338885A 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines Abandoned CA2338885A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9660798P 1998-08-14 1998-08-14
US60/096,607 1998-08-14
PCT/US1999/018575 WO2000009553A2 (fr) 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines

Publications (1)

Publication Number Publication Date
CA2338885A1 true CA2338885A1 (fr) 2000-02-24

Family

ID=22258186

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002338885A Abandoned CA2338885A1 (fr) 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines

Country Status (5)

Country Link
EP (1) EP1104437A2 (fr)
JP (1) JP2002522556A (fr)
AU (1) AU5564299A (fr)
CA (1) CA2338885A1 (fr)
WO (1) WO2000009553A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058942A1 (fr) * 2000-02-11 2001-08-16 Bionebraska, Inc. Peptides antimicrobiens isoles de la peau de la grenouille hyperolius, kassina senegalensis
WO2003091429A1 (fr) 2002-04-25 2003-11-06 Toagosei Co.,Ltd. Polypeptide microbicide et ses utilisations
CN1269837C (zh) * 2002-09-02 2006-08-16 上海高科联合生物技术研发有限公司 一组合成抗菌肽
US7674771B2 (en) 2003-10-29 2010-03-09 Toagosei Co., Ltd Antimicrobial peptides and utilization of the same
US7603239B2 (en) 2004-05-05 2009-10-13 Massachusetts Institute Of Technology Methods and systems for generating peptides
JP4507080B2 (ja) 2004-07-30 2010-07-21 東亞合成株式会社 抗菌ペプチド及びその利用
JP4730584B2 (ja) 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
US20090030179A1 (en) 2005-02-15 2009-01-29 Toagosei Co., Ltd Antimicrobial peptide and use thereof
WO2007061850A2 (fr) * 2005-11-17 2007-05-31 Massachusetts Institute Of Technology Procedes et systemes de generation et d'evaluation de peptides
KR100794499B1 (ko) * 2006-05-16 2008-01-16 주식회사 프로메디텍 개구린 5로부터 합성 및 제조된 항생 및 항암 신규펩타이드 유도체
WO2009148294A1 (fr) * 2008-06-04 2009-12-10 Islas Rodriguez Alfonso Enriqu Extrait de peau de rana catesbeiana, composé et méthode pour le traitement de la mammite bovine
CN102250216B (zh) * 2011-06-27 2013-03-06 昆明理工大学 黑斑蛙抗微生物肽及其基因和应用
GB201401673D0 (en) * 2014-01-31 2014-03-19 Univ Ulster Esculentin-2CHa peptide and analogues thereof
CN110386961B (zh) * 2019-08-29 2022-05-10 昆明医科大学 一种皮肤修复多肽rl-rl10及其应用
CN112042879A (zh) * 2020-09-17 2020-12-08 湖南富高农业科技开发有限公司 一种咸蛋黄炸蛙皮及其制作方法
CN113855783B (zh) * 2021-11-09 2023-02-21 中国药科大学 一种多肽在制备抗肿瘤药物中的应用
CN115246877A (zh) * 2021-12-27 2022-10-28 昆明理工大学 一种黑斑蛙来源抗菌肽Brevinin-1EG及应用
CN115819515B (zh) * 2022-11-30 2023-10-20 四川大学华西医院 一种抗菌肽及其制备方法与应用
CN117338956B (zh) * 2023-11-08 2024-03-05 山东第一医科大学附属眼科医院(山东省眼科医院) 一种用于治疗铜绿假单胞菌性角膜炎的级联免疫调控纳米药物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225399A (en) * 1991-04-15 1993-07-06 The Children's Hospital Of Philadelphia Antimicrobial amphiphilic peptides
SE9604593D0 (sv) * 1996-12-13 1996-12-13 Sbl Vaccin Ab Antimicrobially active polypeptides

Also Published As

Publication number Publication date
JP2002522556A (ja) 2002-07-23
WO2000009553A3 (fr) 2000-05-18
EP1104437A2 (fr) 2001-06-06
AU5564299A (en) 2000-03-06
WO2000009553A2 (fr) 2000-02-24

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