WO2000009553A3 - Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines - Google Patents

Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines Download PDF

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Publication number
WO2000009553A3
WO2000009553A3 PCT/US1999/018575 US9918575W WO0009553A3 WO 2000009553 A3 WO2000009553 A3 WO 2000009553A3 US 9918575 W US9918575 W US 9918575W WO 0009553 A3 WO0009553 A3 WO 0009553A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
antimicrobial peptides
peptides isolated
frogs
american
Prior art date
Application number
PCT/US1999/018575
Other languages
English (en)
Other versions
WO2000009553A2 (fr
Inventor
J Michael Conlon
Original Assignee
Bionebraska Inc
J Michael Conlon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bionebraska Inc, J Michael Conlon filed Critical Bionebraska Inc
Priority to JP2000565002A priority Critical patent/JP2002522556A/ja
Priority to EP99942213A priority patent/EP1104437A2/fr
Priority to AU55642/99A priority patent/AU5564299A/en
Priority to CA002338885A priority patent/CA2338885A1/fr
Publication of WO2000009553A2 publication Critical patent/WO2000009553A2/fr
Publication of WO2000009553A3 publication Critical patent/WO2000009553A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne sept familles de peptides Rana isolés à partir de la peau de six espèces de grenouilles américaines, ainsi que leurs versions modifiées et tronquées. Ces peptides sont dénommés peptides Rana et possèdent une activité antibactérienne.
PCT/US1999/018575 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines WO2000009553A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000565002A JP2002522556A (ja) 1998-08-14 1999-08-13 アメリカカエルの皮膚から単離された抗菌性ペプチド
EP99942213A EP1104437A2 (fr) 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines
AU55642/99A AU5564299A (en) 1998-08-14 1999-08-13 Antimicrobial peptides isolated from the skin of american frogs
CA002338885A CA2338885A1 (fr) 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9660798P 1998-08-14 1998-08-14
US60/096,607 1998-08-14

Publications (2)

Publication Number Publication Date
WO2000009553A2 WO2000009553A2 (fr) 2000-02-24
WO2000009553A3 true WO2000009553A3 (fr) 2000-05-18

Family

ID=22258186

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/018575 WO2000009553A2 (fr) 1998-08-14 1999-08-13 Peptides antimicrobiens isoles a partir de la peau de grenouilles americaines

Country Status (5)

Country Link
EP (1) EP1104437A2 (fr)
JP (1) JP2002522556A (fr)
AU (1) AU5564299A (fr)
CA (1) CA2338885A1 (fr)
WO (1) WO2000009553A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001234947A1 (en) * 2000-02-11 2001-08-20 Bionebraska, Inc. Antimicrobial peptides isolated from the skin of the hyperoliid frog, kassina senegalensis
ATE489462T1 (de) 2002-04-25 2010-12-15 Toagosei Co Ltd Antimikrobielles polypeptid und nutzung davon
CN1269837C (zh) * 2002-09-02 2006-08-16 上海高科联合生物技术研发有限公司 一组合成抗菌肽
WO2005049819A1 (fr) 2003-10-29 2005-06-02 Toagosei Co., Ltd. Peptide antibacterien et utilisation associee
WO2005109158A2 (fr) 2004-05-05 2005-11-17 Massachusetts Institute Of Technology Procedes et systemes de generation de peptides
JP4507080B2 (ja) 2004-07-30 2010-07-21 東亞合成株式会社 抗菌ペプチド及びその利用
JP4730584B2 (ja) 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
WO2006088010A1 (fr) 2005-02-15 2006-08-24 Toagosei Co., Ltd. Peptide antimicrobien et emploi dudit peptide
US7739055B2 (en) 2005-11-17 2010-06-15 Massachusetts Institute Of Technology Methods and systems for generating and evaluating peptides
KR100794499B1 (ko) * 2006-05-16 2008-01-16 주식회사 프로메디텍 개구린 ５로부터 합성 및 제조된 항생 및 항암 신규펩타이드 유도체
WO2009148294A1 (fr) * 2008-06-04 2009-12-10 Islas Rodriguez Alfonso Enriqu Extrait de peau de rana catesbeiana, composé et méthode pour le traitement de la mammite bovine
CN102250216B (zh) * 2011-06-27 2013-03-06 昆明理工大学 黑斑蛙抗微生物肽及其基因和应用
GB201401673D0 (en) 2014-01-31 2014-03-19 Univ Ulster Esculentin-2CHa peptide and analogues thereof
CN110386961B (zh) * 2019-08-29 2022-05-10 昆明医科大学 一种皮肤修复多肽rl-rl10及其应用
CN112042879A (zh) * 2020-09-17 2020-12-08 湖南富高农业科技开发有限公司 一种咸蛋黄炸蛙皮及其制作方法
CN113855783B (zh) * 2021-11-09 2023-02-21 中国药科大学 一种多肽在制备抗肿瘤药物中的应用
CN115246877A (zh) * 2021-12-27 2022-10-28 昆明理工大学 一种黑斑蛙来源抗菌肽Brevinin-1EG及应用
CN115819515B (zh) * 2022-11-30 2023-10-20 四川大学华西医院 一种抗菌肽及其制备方法与应用
CN117338956B (zh) * 2023-11-08 2024-03-05 山东第一医科大学附属眼科医院(山东省眼科医院) 一种用于治疗铜绿假单胞菌性角膜炎的级联免疫调控纳米药物及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018146A1 (fr) * 1991-04-15 1992-10-29 The Children's Hospital Of Philadelphia Compositions de nouveaux peptides biologiquement actifs et leurs utilisations
WO1998025961A1 (fr) * 1996-12-13 1998-06-18 Sbl Vaccin Ab Polypeptides ayant une action antimicrobienne

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018146A1 (fr) * 1991-04-15 1992-10-29 The Children's Hospital Of Philadelphia Compositions de nouveaux peptides biologiquement actifs et leurs utilisations
WO1998025961A1 (fr) * 1996-12-13 1998-06-18 Sbl Vaccin Ab Polypeptides ayant une action antimicrobienne

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DOUGLAS P. CLARK ET AL.: "A novel antimicrobial peptide from bullfrog (Rana catesbeiana) skin, structurally related to the bacterial antibiotic, Polymyxin", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 14, 8 April 1994 (1994-04-08), MD US, pages 10849 - 10855, XP002124375 *
GORAYA J ET AL: "Ranatuerins: antimicrobial peptides isolated from the skin of the America bullfrog, Rana catesbeiana.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (1998 SEP 29) 250 (3 589-92., XP002124378 *
MAURIZIO SIMMACO ET AL.: "Antimicrobial peptides from skin scretions of Rana esculenta", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 16, 22 April 1994 (1994-04-22), MD US, pages 11956 - 11961, XP002124376 *
MAURIZIO SIMMACO ET AL.: "Temporins, antimicrobial peptides from the European red frog Rana temporaria", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 242, no. 3, December 1996 (1996-12-01), pages 788 - 792, XP000856339 *
NORIYUKI MORIKAWA ET AL.: "Brevinin-1 and -2, unique antimicrobial peptides from the skin of the frog, Rana brevipoda porsa", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 189, no. 1, 30 November 1992 (1992-11-30), ORLANDO, FL US, pages 184 - 190, XP002124377 *

Also Published As

Publication number Publication date
JP2002522556A (ja) 2002-07-23
EP1104437A2 (fr) 2001-06-06
WO2000009553A2 (fr) 2000-02-24
AU5564299A (en) 2000-03-06
CA2338885A1 (fr) 2000-02-24

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