CA2315066A1 - Process for the preparation of paroxetine hydrochloride - Google Patents

Process for the preparation of paroxetine hydrochloride Download PDF

Info

Publication number
CA2315066A1
CA2315066A1 CA002315066A CA2315066A CA2315066A1 CA 2315066 A1 CA2315066 A1 CA 2315066A1 CA 002315066 A CA002315066 A CA 002315066A CA 2315066 A CA2315066 A CA 2315066A CA 2315066 A1 CA2315066 A1 CA 2315066A1
Authority
CA
Canada
Prior art keywords
paroxetine hydrochloride
propan
solvate
preparation
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002315066A
Other languages
English (en)
French (fr)
Inventor
David Alan Jones
Neal Ward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2315066A1 publication Critical patent/CA2315066A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002315066A 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride Abandoned CA2315066A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9726907.0A GB9726907D0 (en) 1997-12-19 1997-12-19 Novel compounds
GB9726907.0 1997-12-19
PCT/GB1998/003836 WO1999032484A1 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride

Publications (1)

Publication Number Publication Date
CA2315066A1 true CA2315066A1 (en) 1999-07-01

Family

ID=10823933

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002315066A Abandoned CA2315066A1 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride

Country Status (20)

Country Link
EP (1) EP1042318A1 (no)
JP (1) JP2001526288A (no)
KR (1) KR20010033317A (no)
CN (1) CN1281448A (no)
AP (1) AP2000001836A0 (no)
AU (1) AU1769899A (no)
BG (1) BG104604A (no)
BR (1) BR9813638A (no)
CA (1) CA2315066A1 (no)
EA (1) EA200000689A1 (no)
GB (1) GB9726907D0 (no)
HU (1) HUP0004503A3 (no)
ID (1) ID24733A (no)
IL (1) IL136590A0 (no)
NO (1) NO20003145L (no)
OA (1) OA11635A (no)
PL (1) PL341358A1 (no)
SK (1) SK9242000A3 (no)
TR (1) TR200001933T2 (no)
WO (1) WO1999032484A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
NL1017421C2 (nl) 2001-02-21 2002-01-15 Synthon Bv Werkwijze voor het vervaardigen van paroxetine.
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
KR100672184B1 (ko) 2004-09-21 2007-01-19 주식회사종근당 파록세틴의 콜린산 또는 콜린산 유도체 염

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3688827T2 (de) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
CA2187128A1 (en) * 1996-10-04 1997-06-26 K. S. Keshava Murthy New and useful polymorph of anhydrous paroxetine hydrochloride

Also Published As

Publication number Publication date
CN1281448A (zh) 2001-01-24
WO1999032484A1 (en) 1999-07-01
EP1042318A1 (en) 2000-10-11
IL136590A0 (en) 2001-06-14
SK9242000A3 (en) 2001-01-18
ID24733A (id) 2000-08-03
TR200001933T2 (tr) 2000-12-21
AP2000001836A0 (en) 2000-06-30
PL341358A1 (en) 2001-04-09
OA11635A (en) 2004-11-22
BR9813638A (pt) 2000-10-17
NO20003145D0 (no) 2000-06-16
GB9726907D0 (en) 1998-02-18
HUP0004503A2 (hu) 2002-03-28
JP2001526288A (ja) 2001-12-18
AU1769899A (en) 1999-07-12
BG104604A (en) 2001-03-30
KR20010033317A (ko) 2001-04-25
HUP0004503A3 (en) 2002-04-29
NO20003145L (no) 2000-06-16
EA200000689A1 (ru) 2000-12-25

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Legal Events

Date Code Title Description
FZDE Discontinued