AP2000001836A0 - Process for the preparation of paroxetine hydrochloride. - Google Patents
Process for the preparation of paroxetine hydrochloride.Info
- Publication number
- AP2000001836A0 AP2000001836A0 APAP/P/2000/001836A AP2000001836A AP2000001836A0 AP 2000001836 A0 AP2000001836 A0 AP 2000001836A0 AP 2000001836 A AP2000001836 A AP 2000001836A AP 2000001836 A0 AP2000001836 A0 AP 2000001836A0
- Authority
- AP
- ARIPO
- Prior art keywords
- paroxetine hydrochloride
- preparation
- propan
- solution
- solvate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A process for the preparation of paroxetine hydrochloride propan-2-oi solvate comprises forming a solution of paroxetine hydrochloride in a mixture of propan-2-oi and an effective co-solvent, and crystallising paroxetine hydrochloride propan-2-oi solvate from the solution.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9726907.0A GB9726907D0 (en) | 1997-12-19 | 1997-12-19 | Novel compounds |
PCT/GB1998/003836 WO1999032484A1 (en) | 1997-12-19 | 1998-12-18 | Process for the preparation of paroxetine hydrochloride |
Publications (1)
Publication Number | Publication Date |
---|---|
AP2000001836A0 true AP2000001836A0 (en) | 2000-06-30 |
Family
ID=10823933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/2000/001836A AP2000001836A0 (en) | 1997-12-19 | 1998-12-18 | Process for the preparation of paroxetine hydrochloride. |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1042318A1 (en) |
JP (1) | JP2001526288A (en) |
KR (1) | KR20010033317A (en) |
CN (1) | CN1281448A (en) |
AP (1) | AP2000001836A0 (en) |
AU (1) | AU1769899A (en) |
BG (1) | BG104604A (en) |
BR (1) | BR9813638A (en) |
CA (1) | CA2315066A1 (en) |
EA (1) | EA200000689A1 (en) |
GB (1) | GB9726907D0 (en) |
HU (1) | HUP0004503A3 (en) |
ID (1) | ID24733A (en) |
IL (1) | IL136590A0 (en) |
NO (1) | NO20003145D0 (en) |
OA (1) | OA11635A (en) |
PL (1) | PL341358A1 (en) |
SK (1) | SK9242000A3 (en) |
TR (1) | TR200001933T2 (en) |
WO (1) | WO1999032484A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9919001D0 (en) * | 1999-08-12 | 1999-10-13 | Smithkline Beecham Plc | Novel process |
GB9923439D0 (en) * | 1999-10-04 | 1999-12-08 | Smithkline Beecham Plc | Novel process |
NL1017421C2 (en) | 2001-02-21 | 2002-01-15 | Synthon Bv | Process for the production of paroxetine. |
JP2005524656A (en) * | 2002-02-22 | 2005-08-18 | テバ ファーマシューティカル インダストリーズ リミティド | Preparation of paroxetine using a novel intermediate |
KR100672184B1 (en) | 2004-09-21 | 2007-01-19 | 주식회사종근당 | Paroxetine cholate or cholic acid derivative salts |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0223403B1 (en) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidine derivative, its preparation, and its use as medicament |
AR001982A1 (en) * | 1995-02-06 | 1998-01-07 | Smithkline Beecham Plc | PAROXETINE CHLORHYDRATE ANHYDRATED, AND PROCEDURE FOR ITS PREPARATION |
CA2187128A1 (en) * | 1996-10-04 | 1997-06-26 | K. S. Keshava Murthy | New and useful polymorph of anhydrous paroxetine hydrochloride |
-
1997
- 1997-12-19 GB GBGB9726907.0A patent/GB9726907D0/en not_active Ceased
-
1998
- 1998-12-18 IL IL13659098A patent/IL136590A0/en unknown
- 1998-12-18 ID IDW20001158A patent/ID24733A/en unknown
- 1998-12-18 KR KR1020007006764A patent/KR20010033317A/en not_active Application Discontinuation
- 1998-12-18 PL PL98341358A patent/PL341358A1/en unknown
- 1998-12-18 TR TR2000/01933T patent/TR200001933T2/en unknown
- 1998-12-18 CA CA002315066A patent/CA2315066A1/en not_active Abandoned
- 1998-12-18 SK SK924-2000A patent/SK9242000A3/en unknown
- 1998-12-18 HU HU0004503A patent/HUP0004503A3/en unknown
- 1998-12-18 EP EP98962563A patent/EP1042318A1/en not_active Withdrawn
- 1998-12-18 AP APAP/P/2000/001836A patent/AP2000001836A0/en unknown
- 1998-12-18 AU AU17698/99A patent/AU1769899A/en not_active Abandoned
- 1998-12-18 BR BR9813638-0A patent/BR9813638A/en not_active Application Discontinuation
- 1998-12-18 WO PCT/GB1998/003836 patent/WO1999032484A1/en not_active Application Discontinuation
- 1998-12-18 JP JP2000525421A patent/JP2001526288A/en active Pending
- 1998-12-18 EA EA200000689A patent/EA200000689A1/en unknown
- 1998-12-18 CN CN98811920A patent/CN1281448A/en active Pending
- 1998-12-18 OA OA1200000182A patent/OA11635A/en unknown
-
2000
- 2000-06-16 NO NO20003145A patent/NO20003145D0/en not_active Application Discontinuation
- 2000-07-13 BG BG104604A patent/BG104604A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR9813638A (en) | 2000-10-17 |
OA11635A (en) | 2004-11-22 |
TR200001933T2 (en) | 2000-12-21 |
SK9242000A3 (en) | 2001-01-18 |
CN1281448A (en) | 2001-01-24 |
PL341358A1 (en) | 2001-04-09 |
NO20003145L (en) | 2000-06-16 |
EP1042318A1 (en) | 2000-10-11 |
EA200000689A1 (en) | 2000-12-25 |
KR20010033317A (en) | 2001-04-25 |
GB9726907D0 (en) | 1998-02-18 |
IL136590A0 (en) | 2001-06-14 |
HUP0004503A3 (en) | 2002-04-29 |
AU1769899A (en) | 1999-07-12 |
JP2001526288A (en) | 2001-12-18 |
HUP0004503A2 (en) | 2002-03-28 |
WO1999032484A1 (en) | 1999-07-01 |
NO20003145D0 (en) | 2000-06-16 |
ID24733A (en) | 2000-08-03 |
CA2315066A1 (en) | 1999-07-01 |
BG104604A (en) | 2001-03-30 |
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