TR200001933T2 - Paroxetine hydrochloride preparation process. - Google Patents

Paroxetine hydrochloride preparation process.

Info

Publication number
TR200001933T2
TR200001933T2 TR2000/01933T TR200001933T TR200001933T2 TR 200001933 T2 TR200001933 T2 TR 200001933T2 TR 2000/01933 T TR2000/01933 T TR 2000/01933T TR 200001933 T TR200001933 T TR 200001933T TR 200001933 T2 TR200001933 T2 TR 200001933T2
Authority
TR
Turkey
Prior art keywords
paroxetine hydrochloride
preparation process
hydrochloride preparation
propan
solvate
Prior art date
Application number
TR2000/01933T
Other languages
Turkish (tr)
Inventor
Ward Neal
Alan Jones David
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of TR200001933T2 publication Critical patent/TR200001933T2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Paroksetin hidroklorid propan-2-ol solvatinin hazirlanma prosesi, bir propan-2-ol ile etkili bir ko-solvent karisimindan bir paroksetin hidroklorid solüsyonu olusturulmasini ve bu solüsyondan paroksetin hidroklorid propan-2-ol solvatinin kristallestirilmesini içerir.The preparation process of paroxetine hydrochloride propan-2-ol solvate involves the creation of a paroxetine hydrochloride solution from an effective co-solvent mixture with a propan-2-ol and crystallization of the paroxetine hydrochloride propan-2-ol solvate from this solution.

TR2000/01933T 1997-12-19 1998-12-18 Paroxetine hydrochloride preparation process. TR200001933T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9726907.0A GB9726907D0 (en) 1997-12-19 1997-12-19 Novel compounds

Publications (1)

Publication Number Publication Date
TR200001933T2 true TR200001933T2 (en) 2000-12-21

Family

ID=10823933

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01933T TR200001933T2 (en) 1997-12-19 1998-12-18 Paroxetine hydrochloride preparation process.

Country Status (20)

Country Link
EP (1) EP1042318A1 (en)
JP (1) JP2001526288A (en)
KR (1) KR20010033317A (en)
CN (1) CN1281448A (en)
AP (1) AP2000001836A0 (en)
AU (1) AU1769899A (en)
BG (1) BG104604A (en)
BR (1) BR9813638A (en)
CA (1) CA2315066A1 (en)
EA (1) EA200000689A1 (en)
GB (1) GB9726907D0 (en)
HU (1) HUP0004503A3 (en)
ID (1) ID24733A (en)
IL (1) IL136590A0 (en)
NO (1) NO20003145L (en)
OA (1) OA11635A (en)
PL (1) PL341358A1 (en)
SK (1) SK9242000A3 (en)
TR (1) TR200001933T2 (en)
WO (1) WO1999032484A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
NL1017421C2 (en) 2001-02-21 2002-01-15 Synthon Bv Process for the production of paroxetine.
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
KR100672184B1 (en) 2004-09-21 2007-01-19 주식회사종근당 Paroxetine cholate or cholic acid derivative salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3688827T2 (en) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidine derivative, its manufacture and its use as a medicine.
SK283608B6 (en) * 1995-02-06 2003-10-07 Smithkline Beecham Plc New forms of parotexin hydrochloride
CA2187128A1 (en) * 1996-10-04 1997-06-26 K. S. Keshava Murthy New and useful polymorph of anhydrous paroxetine hydrochloride

Also Published As

Publication number Publication date
CN1281448A (en) 2001-01-24
WO1999032484A1 (en) 1999-07-01
EP1042318A1 (en) 2000-10-11
IL136590A0 (en) 2001-06-14
SK9242000A3 (en) 2001-01-18
ID24733A (en) 2000-08-03
CA2315066A1 (en) 1999-07-01
AP2000001836A0 (en) 2000-06-30
PL341358A1 (en) 2001-04-09
OA11635A (en) 2004-11-22
BR9813638A (en) 2000-10-17
NO20003145D0 (en) 2000-06-16
GB9726907D0 (en) 1998-02-18
HUP0004503A2 (en) 2002-03-28
JP2001526288A (en) 2001-12-18
AU1769899A (en) 1999-07-12
BG104604A (en) 2001-03-30
KR20010033317A (en) 2001-04-25
HUP0004503A3 (en) 2002-04-29
NO20003145L (en) 2000-06-16
EA200000689A1 (en) 2000-12-25

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