NO20003145L - Process for the preparation of paroxetine hydrochloride - Google Patents

Process for the preparation of paroxetine hydrochloride

Info

Publication number
NO20003145L
NO20003145L NO20003145A NO20003145A NO20003145L NO 20003145 L NO20003145 L NO 20003145L NO 20003145 A NO20003145 A NO 20003145A NO 20003145 A NO20003145 A NO 20003145A NO 20003145 L NO20003145 L NO 20003145L
Authority
NO
Norway
Prior art keywords
paroxetine hydrochloride
preparation
propan
solution
solvate
Prior art date
Application number
NO20003145A
Other languages
Norwegian (no)
Other versions
NO20003145D0 (en
Inventor
Neal Ward
Alan David Jones
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO20003145D0 publication Critical patent/NO20003145D0/en
Publication of NO20003145L publication Critical patent/NO20003145L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

En fremgangsmåte for fremstilling av paroxetine-hydroklorid propan-2-ol- solvat omfatter dannelse av en løsning av paroxetine-hydroklorid i en blanding av propan-2-ol og et effektivt co-løsningsmiddel og krystallisering av paroxetine-hydroklorid propan-2-ol-solvat fra løsningen.A process for the preparation of paroxetine hydrochloride propan-2-ol solvate comprises the formation of a solution of paroxetine hydrochloride in a mixture of propan-2-ol and an effective co-solvent and crystallization of paroxetine hydrochloride propan-2-ol. -solvate from the solution.

NO20003145A 1997-12-19 2000-06-16 Process for the preparation of paroxetine hydrochloride NO20003145L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726907.0A GB9726907D0 (en) 1997-12-19 1997-12-19 Novel compounds
PCT/GB1998/003836 WO1999032484A1 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride

Publications (2)

Publication Number Publication Date
NO20003145D0 NO20003145D0 (en) 2000-06-16
NO20003145L true NO20003145L (en) 2000-06-16

Family

ID=10823933

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003145A NO20003145L (en) 1997-12-19 2000-06-16 Process for the preparation of paroxetine hydrochloride

Country Status (20)

Country Link
EP (1) EP1042318A1 (en)
JP (1) JP2001526288A (en)
KR (1) KR20010033317A (en)
CN (1) CN1281448A (en)
AP (1) AP2000001836A0 (en)
AU (1) AU1769899A (en)
BG (1) BG104604A (en)
BR (1) BR9813638A (en)
CA (1) CA2315066A1 (en)
EA (1) EA200000689A1 (en)
GB (1) GB9726907D0 (en)
HU (1) HUP0004503A3 (en)
ID (1) ID24733A (en)
IL (1) IL136590A0 (en)
NO (1) NO20003145L (en)
OA (1) OA11635A (en)
PL (1) PL341358A1 (en)
SK (1) SK9242000A3 (en)
TR (1) TR200001933T2 (en)
WO (1) WO1999032484A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
NL1017421C2 (en) 2001-02-21 2002-01-15 Synthon Bv Process for the production of paroxetine.
JP2005524656A (en) * 2002-02-22 2005-08-18 テバ ファーマシューティカル インダストリーズ リミティド Preparation of paroxetine using a novel intermediate
KR100672184B1 (en) 2004-09-21 2007-01-19 주식회사종근당 Paroxetine cholate or cholic acid derivative salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
SK283608B6 (en) * 1995-02-06 2003-10-07 Smithkline Beecham Plc New forms of parotexin hydrochloride
CA2187128A1 (en) * 1996-10-04 1997-06-26 K. S. Keshava Murthy New and useful polymorph of anhydrous paroxetine hydrochloride

Also Published As

Publication number Publication date
HUP0004503A2 (en) 2002-03-28
EP1042318A1 (en) 2000-10-11
ID24733A (en) 2000-08-03
SK9242000A3 (en) 2001-01-18
EA200000689A1 (en) 2000-12-25
OA11635A (en) 2004-11-22
AU1769899A (en) 1999-07-12
BR9813638A (en) 2000-10-17
GB9726907D0 (en) 1998-02-18
IL136590A0 (en) 2001-06-14
WO1999032484A1 (en) 1999-07-01
KR20010033317A (en) 2001-04-25
CN1281448A (en) 2001-01-24
TR200001933T2 (en) 2000-12-21
AP2000001836A0 (en) 2000-06-30
CA2315066A1 (en) 1999-07-01
HUP0004503A3 (en) 2002-04-29
NO20003145D0 (en) 2000-06-16
JP2001526288A (en) 2001-12-18
PL341358A1 (en) 2001-04-09
BG104604A (en) 2001-03-30

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application