BR9813638A - "process for the preparation of paroxetine hydrochloride" - Google Patents

"process for the preparation of paroxetine hydrochloride"

Info

Publication number
BR9813638A
BR9813638A BR9813638-0A BR9813638A BR9813638A BR 9813638 A BR9813638 A BR 9813638A BR 9813638 A BR9813638 A BR 9813638A BR 9813638 A BR9813638 A BR 9813638A
Authority
BR
Brazil
Prior art keywords
preparation
paroxetine hydrochloride
paroxetine
propan
solution
Prior art date
Application number
BR9813638-0A
Other languages
Portuguese (pt)
Inventor
Neal Ward
Alan David Jones
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR9813638A publication Critical patent/BR9813638A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE CLORIDRATO DE PAROXETINA" A presente invenção refere-se a um processo para a preparação de solvato de cloridrato de paroxetina propan-2-ol que compreende formar uma solução de cloridrato de paroxetina em uma mistura de propan-2-ol e co-solvente eficaz, e cristalizar solvato de cloridrato de paroxetina propan-2-ol a partir da solução."PROCESS FOR THE PREPARATION OF PAROXETINE CHLORIDRATE" The present invention relates to a process for the preparation of paroxetine hydrochloride propan-2-ol which comprises forming a solution of paroxetine hydrochloride in a mixture of propan-2-ol ol and effective co-solvent, and crystallize paroxetine hydrochloride propan-2-ol solvate from the solution.

BR9813638-0A 1997-12-19 1998-12-18 "process for the preparation of paroxetine hydrochloride" BR9813638A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726907.0A GB9726907D0 (en) 1997-12-19 1997-12-19 Novel compounds
PCT/GB1998/003836 WO1999032484A1 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride

Publications (1)

Publication Number Publication Date
BR9813638A true BR9813638A (en) 2000-10-17

Family

ID=10823933

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9813638-0A BR9813638A (en) 1997-12-19 1998-12-18 "process for the preparation of paroxetine hydrochloride"

Country Status (20)

Country Link
EP (1) EP1042318A1 (en)
JP (1) JP2001526288A (en)
KR (1) KR20010033317A (en)
CN (1) CN1281448A (en)
AP (1) AP2000001836A0 (en)
AU (1) AU1769899A (en)
BG (1) BG104604A (en)
BR (1) BR9813638A (en)
CA (1) CA2315066A1 (en)
EA (1) EA200000689A1 (en)
GB (1) GB9726907D0 (en)
HU (1) HUP0004503A3 (en)
ID (1) ID24733A (en)
IL (1) IL136590A0 (en)
NO (1) NO20003145L (en)
OA (1) OA11635A (en)
PL (1) PL341358A1 (en)
SK (1) SK9242000A3 (en)
TR (1) TR200001933T2 (en)
WO (1) WO1999032484A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
NL1017421C2 (en) 2001-02-21 2002-01-15 Synthon Bv Process for the production of paroxetine.
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
KR100672184B1 (en) 2004-09-21 2007-01-19 주식회사종근당 Paroxetine cholate or cholic acid derivative salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3688827T2 (en) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidine derivative, its manufacture and its use as a medicine.
SK283608B6 (en) * 1995-02-06 2003-10-07 Smithkline Beecham Plc New forms of parotexin hydrochloride
CA2187128A1 (en) * 1996-10-04 1997-06-26 K. S. Keshava Murthy New and useful polymorph of anhydrous paroxetine hydrochloride

Also Published As

Publication number Publication date
CN1281448A (en) 2001-01-24
WO1999032484A1 (en) 1999-07-01
EP1042318A1 (en) 2000-10-11
IL136590A0 (en) 2001-06-14
SK9242000A3 (en) 2001-01-18
ID24733A (en) 2000-08-03
TR200001933T2 (en) 2000-12-21
CA2315066A1 (en) 1999-07-01
AP2000001836A0 (en) 2000-06-30
PL341358A1 (en) 2001-04-09
OA11635A (en) 2004-11-22
NO20003145D0 (en) 2000-06-16
GB9726907D0 (en) 1998-02-18
HUP0004503A2 (en) 2002-03-28
JP2001526288A (en) 2001-12-18
AU1769899A (en) 1999-07-12
BG104604A (en) 2001-03-30
KR20010033317A (en) 2001-04-25
HUP0004503A3 (en) 2002-04-29
NO20003145L (en) 2000-06-16
EA200000689A1 (en) 2000-12-25

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Legal Events

Date Code Title Description
FA Application withdrawn