CA2315066A1 - Procede de preparation d'hydrochlorure de paroxetine - Google Patents
Procede de preparation d'hydrochlorure de paroxetine Download PDFInfo
- Publication number
- CA2315066A1 CA2315066A1 CA002315066A CA2315066A CA2315066A1 CA 2315066 A1 CA2315066 A1 CA 2315066A1 CA 002315066 A CA002315066 A CA 002315066A CA 2315066 A CA2315066 A CA 2315066A CA 2315066 A1 CA2315066 A1 CA 2315066A1
- Authority
- CA
- Canada
- Prior art keywords
- paroxetine hydrochloride
- propan
- solvate
- preparation
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Cette invention concerne un procédé de préparation d'un solvat propan-2-ol d'hydrochlorure de paroxetine, lequel consiste à former une solution d'hydrochlorure de paroxetine dans un mélange comprenant du propan-2-ol et un co-solvant efficace. Le solvat propan-2-ol d'hydrochlorure de paroxetine est ensuite cristallisé à partir de cette solution.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9726907.0 | 1997-12-19 | ||
| GBGB9726907.0A GB9726907D0 (en) | 1997-12-19 | 1997-12-19 | Novel compounds |
| PCT/GB1998/003836 WO1999032484A1 (fr) | 1997-12-19 | 1998-12-18 | Procede de preparation d'hydrochlorure de paroxetine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2315066A1 true CA2315066A1 (fr) | 1999-07-01 |
Family
ID=10823933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002315066A Abandoned CA2315066A1 (fr) | 1997-12-19 | 1998-12-18 | Procede de preparation d'hydrochlorure de paroxetine |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1042318A1 (fr) |
| JP (1) | JP2001526288A (fr) |
| KR (1) | KR20010033317A (fr) |
| CN (1) | CN1281448A (fr) |
| AP (1) | AP2000001836A0 (fr) |
| AU (1) | AU1769899A (fr) |
| BG (1) | BG104604A (fr) |
| BR (1) | BR9813638A (fr) |
| CA (1) | CA2315066A1 (fr) |
| EA (1) | EA200000689A1 (fr) |
| GB (1) | GB9726907D0 (fr) |
| HU (1) | HUP0004503A3 (fr) |
| ID (1) | ID24733A (fr) |
| IL (1) | IL136590A0 (fr) |
| NO (1) | NO20003145D0 (fr) |
| OA (1) | OA11635A (fr) |
| PL (1) | PL341358A1 (fr) |
| SK (1) | SK9242000A3 (fr) |
| TR (1) | TR200001933T2 (fr) |
| WO (1) | WO1999032484A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9919001D0 (en) * | 1999-08-12 | 1999-10-13 | Smithkline Beecham Plc | Novel process |
| GB9923439D0 (en) * | 1999-10-04 | 1999-12-08 | Smithkline Beecham Plc | Novel process |
| NL1017421C2 (nl) | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
| JP2005524656A (ja) * | 2002-02-22 | 2005-08-18 | テバ ファーマシューティカル インダストリーズ リミティド | 新規中間物質を用いるパロキセチンの調製 |
| KR100672184B1 (ko) | 2004-09-21 | 2007-01-19 | 주식회사종근당 | 파록세틴의 콜린산 또는 콜린산 유도체 염 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0223403B1 (fr) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Dérivé de pipéridine, sa préparation et son utilisation comme médicament |
| SK283608B6 (sk) * | 1995-02-06 | 2003-10-07 | Smithkline Beecham Plc | Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie |
| CA2187128A1 (fr) * | 1996-10-04 | 1997-06-26 | K. S. Keshava Murthy | Polymorphe nouveau et efficace, a base de chlorhydrate de paroxetine anhydre |
-
1997
- 1997-12-19 GB GBGB9726907.0A patent/GB9726907D0/en not_active Ceased
-
1998
- 1998-12-18 KR KR1020007006764A patent/KR20010033317A/ko not_active Application Discontinuation
- 1998-12-18 EA EA200000689A patent/EA200000689A1/ru unknown
- 1998-12-18 TR TR2000/01933T patent/TR200001933T2/xx unknown
- 1998-12-18 SK SK924-2000A patent/SK9242000A3/sk unknown
- 1998-12-18 WO PCT/GB1998/003836 patent/WO1999032484A1/fr not_active Application Discontinuation
- 1998-12-18 AP APAP/P/2000/001836A patent/AP2000001836A0/en unknown
- 1998-12-18 OA OA1200000182A patent/OA11635A/en unknown
- 1998-12-18 CN CN98811920A patent/CN1281448A/zh active Pending
- 1998-12-18 AU AU17698/99A patent/AU1769899A/en not_active Abandoned
- 1998-12-18 PL PL98341358A patent/PL341358A1/xx unknown
- 1998-12-18 JP JP2000525421A patent/JP2001526288A/ja active Pending
- 1998-12-18 CA CA002315066A patent/CA2315066A1/fr not_active Abandoned
- 1998-12-18 IL IL13659098A patent/IL136590A0/xx unknown
- 1998-12-18 HU HU0004503A patent/HUP0004503A3/hu unknown
- 1998-12-18 ID IDW20001158A patent/ID24733A/id unknown
- 1998-12-18 BR BR9813638-0A patent/BR9813638A/pt not_active Application Discontinuation
- 1998-12-18 EP EP98962563A patent/EP1042318A1/fr not_active Withdrawn
-
2000
- 2000-06-16 NO NO20003145A patent/NO20003145D0/no not_active Application Discontinuation
- 2000-07-13 BG BG104604A patent/BG104604A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| OA11635A (en) | 2004-11-22 |
| BR9813638A (pt) | 2000-10-17 |
| AP2000001836A0 (en) | 2000-06-30 |
| TR200001933T2 (tr) | 2000-12-21 |
| HUP0004503A3 (en) | 2002-04-29 |
| NO20003145L (no) | 2000-06-16 |
| AU1769899A (en) | 1999-07-12 |
| EP1042318A1 (fr) | 2000-10-11 |
| EA200000689A1 (ru) | 2000-12-25 |
| ID24733A (id) | 2000-08-03 |
| SK9242000A3 (en) | 2001-01-18 |
| KR20010033317A (ko) | 2001-04-25 |
| PL341358A1 (en) | 2001-04-09 |
| BG104604A (en) | 2001-03-30 |
| IL136590A0 (en) | 2001-06-14 |
| NO20003145D0 (no) | 2000-06-16 |
| JP2001526288A (ja) | 2001-12-18 |
| CN1281448A (zh) | 2001-01-24 |
| HUP0004503A2 (hu) | 2002-03-28 |
| GB9726907D0 (en) | 1998-02-18 |
| WO1999032484A1 (fr) | 1999-07-01 |
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| Publication | Publication Date | Title |
|---|---|---|
| CA2315066A1 (fr) | Procede de preparation d'hydrochlorure de paroxetine | |
| MXPA00006040A (en) | Process for the preparation of paroxetine hydrochloride | |
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| EP1187830A1 (fr) | Procede de preparation de paroxetine et composes structurellement apparentes | |
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| EP1135383B1 (fr) | Solvates de paroxetine propan-2-ol melanges | |
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| US20010008940A1 (en) | Novel process | |
| WO2000032595A1 (fr) | Processus de production de solvate acetonique d'hydrochlorure de paroxetine | |
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| MXPA00009137A (es) | Forma cristalina de paroxetina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |