CA2294155A1 - Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals - Google Patents
Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals Download PDFInfo
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- CA2294155A1 CA2294155A1 CA002294155A CA2294155A CA2294155A1 CA 2294155 A1 CA2294155 A1 CA 2294155A1 CA 002294155 A CA002294155 A CA 002294155A CA 2294155 A CA2294155 A CA 2294155A CA 2294155 A1 CA2294155 A1 CA 2294155A1
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US5040297P | 1997-06-20 | 1997-06-20 | |
| US60/050,402 | 1997-06-20 | ||
| PCT/US1998/012231 WO1998058636A1 (en) | 1997-06-20 | 1998-06-15 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals |
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| CA2294155A1 true CA2294155A1 (en) | 1998-12-30 |
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| CA002294155A Abandoned CA2294155A1 (en) | 1997-06-20 | 1998-06-15 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals |
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|---|---|
| US (2) | US6180620B1 (https=) |
| EP (1) | EP1001752B1 (https=) |
| JP (1) | JP2002506445A (https=) |
| AT (1) | ATE256467T1 (https=) |
| AU (1) | AU733415B2 (https=) |
| CA (1) | CA2294155A1 (https=) |
| DE (1) | DE69820633T2 (https=) |
| DK (1) | DK1001752T3 (https=) |
| ES (1) | ES2215305T3 (https=) |
| PT (1) | PT1001752E (https=) |
| WO (1) | WO1998058636A1 (https=) |
| ZA (1) | ZA985376B (https=) |
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| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| US20060270639A1 (en) * | 1997-06-20 | 2006-11-30 | Daniela Salvemini | Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs |
| US6214817B1 (en) * | 1997-06-20 | 2001-04-10 | Monsanto Company | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity |
| US20050171198A1 (en) * | 1997-06-20 | 2005-08-04 | Metaphore Pharmaceuticals, Inc. | SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease |
| IL135949A0 (en) | 1997-11-03 | 2001-05-20 | Univ Duke | Substituted porphyrins |
| DK1616869T3 (da) | 1999-01-25 | 2012-05-07 | Nat Jewish Health | Substituerede porphyriner og deres terapeutiske anvendelse |
| DE60018925T2 (de) | 1999-05-27 | 2006-04-13 | Pharmacia Corp.(N.D.Ges.D.Staates Delaware) | Biomaterialien, modifiziert mit superoxid-dismutase imitatoren |
| US20030069281A1 (en) * | 2000-06-14 | 2003-04-10 | Irwin Fridovich | Tetrapyrroles |
| US20020072512A1 (en) * | 2000-12-08 | 2002-06-13 | Metaphore Pharmaceuticals, Inc | Method of preventing and treating HIV-mediated central nervous system damage |
| DE60235955D1 (de) * | 2001-01-05 | 2010-05-27 | Metaphore Pharmaceuticals Inc | Zusammensetzungen und verfahren zur erhöhung der zytokin-aktivität und zur behandlung der hypotension assoziiert mit der verabreichung von zytokinen |
| EP1392328B1 (en) | 2001-01-19 | 2009-08-12 | National Jewish Medical and Research Center | Medicament for protection in radiotherapy |
| WO2002058686A2 (en) * | 2001-01-26 | 2002-08-01 | Metaphore Pharmaceuticals, Inc. | Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes |
| EP1405066B1 (en) * | 2001-03-02 | 2015-06-17 | Galera Therapeutics LLC | Chromatography of metal complexes |
| US20040137638A1 (en) | 2002-03-04 | 2004-07-15 | Slomczynska Urszula J. | Chromatography of metal complexes |
| AU2002312194B8 (en) * | 2001-06-01 | 2008-05-15 | Aeolus Sciences, Inc. | Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance |
| CA2449631A1 (en) * | 2001-06-08 | 2002-12-19 | Metaphore Pharmaceuticals, Inc. | Libraries of conformationally constrained peptides, chiral azacrowns, and peptidomimetics and methods of making the same |
| CA2451602A1 (en) * | 2001-06-26 | 2003-01-03 | Metaphore Pharmaceuticals, Inc. | Combination therapy of an sodm and a corticosteroid for prevention and/or treatment of inflammatory disease |
| EP1450824A4 (en) * | 2001-11-02 | 2005-09-28 | Elan Corp Plc | PHARMACEUTICAL COMPOSITION |
| SI1463563T1 (sl) * | 2001-12-14 | 2009-06-30 | Alcon Inc | Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni |
| US6933275B2 (en) * | 2002-05-01 | 2005-08-23 | The Board Of Trustees Of The Leland Stanford Junior University | Protein kinase C peptides for use in withdrawal |
| AU2003237500A1 (en) * | 2002-06-07 | 2003-12-22 | Duke University | Substituted porphyrins |
| US20030232784A1 (en) * | 2002-06-14 | 2003-12-18 | Benedict James J. | Hyaluronic acid-associated superoxide dismutase mimics and their use in the treatment of joint pain |
| US6984636B2 (en) * | 2002-08-12 | 2006-01-10 | Medical Research Council | Mitochondrially targeted antioxidants |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0751496B2 (ja) | 1986-04-02 | 1995-06-05 | 武田薬品工業株式会社 | リポソ−ムの製造法 |
| US5216021A (en) | 1986-08-28 | 1993-06-01 | Sorenson John R J | Analgesic method |
| US4999347A (en) | 1986-08-28 | 1991-03-12 | Sorenson John R J | Analgesic method |
| JPS63313581A (ja) * | 1987-06-16 | 1988-12-21 | Ube Ind Ltd | 修飾ス−パ−オキシドジスムタ−ゼ |
| CA2072934C (en) | 1991-07-19 | 2007-08-28 | Karl William Aston | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| ES2113952T3 (es) | 1991-07-19 | 1998-05-16 | Monsanto Co | Complejos de manganeso con ligandos macrociclicos nitrogenados eficaces como catalizadores para dismutar superoxidos. |
| CN1088086A (zh) * | 1992-12-14 | 1994-06-22 | 西北大学 | 一种新型的护肤保健品 |
| US6204259B1 (en) | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| US6525041B1 (en) | 1995-06-06 | 2003-02-25 | Pharmacia Corporation | Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| BR9708179A (pt) | 1996-03-13 | 1999-07-27 | Monsanto Co | Bioconjugados de complexos de manganês ou ferro de ligantes macrociclicos contendo nitrogênio eficazes como catalizadores para desmutar superoxidos |
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1998
- 1998-04-09 US US09/057,831 patent/US6180620B1/en not_active Expired - Fee Related
- 1998-06-15 ES ES98929022T patent/ES2215305T3/es not_active Expired - Lifetime
- 1998-06-15 EP EP98929022A patent/EP1001752B1/en not_active Expired - Lifetime
- 1998-06-15 DE DE69820633T patent/DE69820633T2/de not_active Expired - Fee Related
- 1998-06-15 JP JP50459399A patent/JP2002506445A/ja not_active Ceased
- 1998-06-15 AU AU80685/98A patent/AU733415B2/en not_active Ceased
- 1998-06-15 CA CA002294155A patent/CA2294155A1/en not_active Abandoned
- 1998-06-15 PT PT98929022T patent/PT1001752E/pt unknown
- 1998-06-15 DK DK98929022T patent/DK1001752T3/da active
- 1998-06-15 WO PCT/US1998/012231 patent/WO1998058636A1/en not_active Ceased
- 1998-06-15 AT AT98929022T patent/ATE256467T1/de not_active IP Right Cessation
- 1998-06-19 ZA ZA985376A patent/ZA985376B/xx unknown
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2000
- 2000-08-09 US US09/634,152 patent/US6395725B1/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| US6180620B1 (en) | 2001-01-30 |
| ATE256467T1 (de) | 2004-01-15 |
| ES2215305T3 (es) | 2004-10-01 |
| DK1001752T3 (da) | 2004-04-19 |
| DE69820633T2 (de) | 2004-09-23 |
| DE69820633D1 (de) | 2004-01-29 |
| JP2002506445A (ja) | 2002-02-26 |
| ZA985376B (en) | 1999-06-21 |
| WO1998058636A1 (en) | 1998-12-30 |
| AU733415B2 (en) | 2001-05-17 |
| AU8068598A (en) | 1999-01-04 |
| EP1001752A1 (en) | 2000-05-24 |
| EP1001752B1 (en) | 2003-12-17 |
| US6395725B1 (en) | 2002-05-28 |
| PT1001752E (pt) | 2004-05-31 |
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