CA2294155A1 - Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals - Google Patents
Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals Download PDFInfo
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- CA2294155A1 CA2294155A1 CA002294155A CA2294155A CA2294155A1 CA 2294155 A1 CA2294155 A1 CA 2294155A1 CA 002294155 A CA002294155 A CA 002294155A CA 2294155 A CA2294155 A CA 2294155A CA 2294155 A1 CA2294155 A1 CA 2294155A1
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
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- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US5040297P | 1997-06-20 | 1997-06-20 | |
| US60/050,402 | 1997-06-20 | ||
| PCT/US1998/012231 WO1998058636A1 (en) | 1997-06-20 | 1998-06-15 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals |
Publications (1)
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| CA2294155A1 true CA2294155A1 (en) | 1998-12-30 |
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| CA002294155A Abandoned CA2294155A1 (en) | 1997-06-20 | 1998-06-15 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals |
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|---|---|
| US (2) | US6180620B1 (https=) |
| EP (1) | EP1001752B1 (https=) |
| JP (1) | JP2002506445A (https=) |
| AT (1) | ATE256467T1 (https=) |
| AU (1) | AU733415B2 (https=) |
| CA (1) | CA2294155A1 (https=) |
| DE (1) | DE69820633T2 (https=) |
| DK (1) | DK1001752T3 (https=) |
| ES (1) | ES2215305T3 (https=) |
| PT (1) | PT1001752E (https=) |
| WO (1) | WO1998058636A1 (https=) |
| ZA (1) | ZA985376B (https=) |
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| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| US20050171198A1 (en) * | 1997-06-20 | 2005-08-04 | Metaphore Pharmaceuticals, Inc. | SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease |
| US6214817B1 (en) * | 1997-06-20 | 2001-04-10 | Monsanto Company | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity |
| US20060270639A1 (en) * | 1997-06-20 | 2006-11-30 | Daniela Salvemini | Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs |
| WO1999023097A1 (en) | 1997-11-03 | 1999-05-14 | Duke University | Substituted porphyrins |
| ATE312103T1 (de) | 1999-01-25 | 2005-12-15 | Nat Jewish Med & Res Center | Substituierte porphyrine und deren therapeutische verwendungen |
| AU5048400A (en) * | 1999-05-27 | 2000-12-18 | Monsanto Company | Biomaterials modified with superoxide dismutase mimics |
| US20030069281A1 (en) * | 2000-06-14 | 2003-04-10 | Irwin Fridovich | Tetrapyrroles |
| US20020072512A1 (en) * | 2000-12-08 | 2002-06-13 | Metaphore Pharmaceuticals, Inc | Method of preventing and treating HIV-mediated central nervous system damage |
| JP4331939B2 (ja) * | 2001-01-05 | 2009-09-16 | メタファー・ファーマシューティカルズ・インコーポレイテッド | サイトカイン活性を増強させ、そしてサイトカインの投与に伴う低血圧を治療するための組成物および方法 |
| DE60233317D1 (de) | 2001-01-19 | 2009-09-24 | Nat Jewish Med & Res Center | Medikament zum schutz in der radiotherapie |
| EP1353655A2 (en) * | 2001-01-26 | 2003-10-22 | Metaphore Pharmaceuticals Inc. | Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes |
| CA2439971A1 (en) * | 2001-03-02 | 2002-09-12 | Metaphore Pharmaceuticals, Inc. | Chromatography of metal complexes |
| US20040137638A1 (en) | 2002-03-04 | 2004-07-15 | Slomczynska Urszula J. | Chromatography of metal complexes |
| EP1439842A4 (en) * | 2001-06-01 | 2009-09-02 | Nat Jewish Med & Res Center | OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE |
| US20040236519A1 (en) * | 2001-06-08 | 2004-11-25 | Marshall Garland R. | Libraries of confomationally constrained peptides, chiral azacrowns, and peptidomimetics and methods of making the same |
| CA2451602A1 (en) * | 2001-06-26 | 2003-01-03 | Metaphore Pharmaceuticals, Inc. | Combination therapy of an sodm and a corticosteroid for prevention and/or treatment of inflammatory disease |
| EP1450824A4 (en) * | 2001-11-02 | 2005-09-28 | Elan Corp Plc | PHARMACEUTICAL COMPOSITION |
| WO2003051458A1 (en) * | 2001-12-14 | 2003-06-26 | Alcon, Inc. | Superoxide dismutase mimics for the treatment of ocular disorders and diseases |
| US6933275B2 (en) * | 2002-05-01 | 2005-08-23 | The Board Of Trustees Of The Leland Stanford Junior University | Protein kinase C peptides for use in withdrawal |
| US7485721B2 (en) * | 2002-06-07 | 2009-02-03 | Duke University | Substituted porphyrins |
| US20030232784A1 (en) * | 2002-06-14 | 2003-12-18 | Benedict James J. | Hyaluronic acid-associated superoxide dismutase mimics and their use in the treatment of joint pain |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0751496B2 (ja) | 1986-04-02 | 1995-06-05 | 武田薬品工業株式会社 | リポソ−ムの製造法 |
| US5216021A (en) | 1986-08-28 | 1993-06-01 | Sorenson John R J | Analgesic method |
| US4999347A (en) | 1986-08-28 | 1991-03-12 | Sorenson John R J | Analgesic method |
| JPS63313581A (ja) * | 1987-06-16 | 1988-12-21 | Ube Ind Ltd | 修飾ス−パ−オキシドジスムタ−ゼ |
| CA2072934C (en) | 1991-07-19 | 2007-08-28 | Karl William Aston | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| EP0598753B1 (en) | 1991-07-19 | 1998-03-18 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| CN1088086A (zh) * | 1992-12-14 | 1994-06-22 | 西北大学 | 一种新型的护肤保健品 |
| US6204259B1 (en) | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| US6525041B1 (en) | 1995-06-06 | 2003-02-25 | Pharmacia Corporation | Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| KR19990087784A (ko) | 1996-03-13 | 1999-12-27 | 죤 에이치. 뷰센 | 초과산화물을 불균등화하기 위한 촉매로서 효과적인 질소함유거대고리 리간드의 망간 또는 철착물의 바이오콘쥬게이트 |
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1998
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- 1998-06-15 DE DE69820633T patent/DE69820633T2/de not_active Expired - Fee Related
- 1998-06-15 EP EP98929022A patent/EP1001752B1/en not_active Expired - Lifetime
- 1998-06-15 PT PT98929022T patent/PT1001752E/pt unknown
- 1998-06-15 CA CA002294155A patent/CA2294155A1/en not_active Abandoned
- 1998-06-15 AU AU80685/98A patent/AU733415B2/en not_active Ceased
- 1998-06-15 AT AT98929022T patent/ATE256467T1/de not_active IP Right Cessation
- 1998-06-15 ES ES98929022T patent/ES2215305T3/es not_active Expired - Lifetime
- 1998-06-15 JP JP50459399A patent/JP2002506445A/ja not_active Ceased
- 1998-06-15 WO PCT/US1998/012231 patent/WO1998058636A1/en not_active Ceased
- 1998-06-15 DK DK98929022T patent/DK1001752T3/da active
- 1998-06-19 ZA ZA985376A patent/ZA985376B/xx unknown
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2000
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| PT1001752E (pt) | 2004-05-31 |
| DE69820633D1 (de) | 2004-01-29 |
| AU8068598A (en) | 1999-01-04 |
| ATE256467T1 (de) | 2004-01-15 |
| ZA985376B (en) | 1999-06-21 |
| AU733415B2 (en) | 2001-05-17 |
| JP2002506445A (ja) | 2002-02-26 |
| WO1998058636A1 (en) | 1998-12-30 |
| EP1001752A1 (en) | 2000-05-24 |
| EP1001752B1 (en) | 2003-12-17 |
| US6395725B1 (en) | 2002-05-28 |
| US6180620B1 (en) | 2001-01-30 |
| DK1001752T3 (da) | 2004-04-19 |
| ES2215305T3 (es) | 2004-10-01 |
| DE69820633T2 (de) | 2004-09-23 |
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