CA2290824A1 - Composition pharmaceutique contenant du benzimidazole et procede de preparation - Google Patents

Composition pharmaceutique contenant du benzimidazole et procede de preparation Download PDF

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Publication number
CA2290824A1
CA2290824A1 CA002290824A CA2290824A CA2290824A1 CA 2290824 A1 CA2290824 A1 CA 2290824A1 CA 002290824 A CA002290824 A CA 002290824A CA 2290824 A CA2290824 A CA 2290824A CA 2290824 A1 CA2290824 A1 CA 2290824A1
Authority
CA
Canada
Prior art keywords
benzimidazole
moisture resistant
resistant coating
core
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002290824A
Other languages
English (en)
Inventor
Yusuf Khwaja Hamied
Geena Malhotra
Vinay G. Nayak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2290824A1 publication Critical patent/CA2290824A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une composition pharmaceutique qui est un pellet solide contenant un noyau inerte; un benzimidazole situé dans ou sur ledit noyau; un enrobage résistant à l'humidité recouvrant ledit noyau et contenant au moins une matière hydrophobe; et un revêtement gastro-résistant recouvrant ledit enrobage résistant à l'humidité.
CA002290824A 1997-05-23 1998-05-21 Composition pharmaceutique contenant du benzimidazole et procede de preparation Abandoned CA2290824A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9710800.5A GB9710800D0 (en) 1997-05-23 1997-05-23 Pharmaceutical composition and method of preparing it
GB9710800.5 1997-05-23
PCT/GB1998/001465 WO1998052564A1 (fr) 1997-05-23 1998-05-21 Composition pharmaceutique contenant du benzimidazole et procede de preparation

Publications (1)

Publication Number Publication Date
CA2290824A1 true CA2290824A1 (fr) 1998-11-26

Family

ID=10813043

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002290824A Abandoned CA2290824A1 (fr) 1997-05-23 1998-05-21 Composition pharmaceutique contenant du benzimidazole et procede de preparation

Country Status (6)

Country Link
EP (1) EP0983067A1 (fr)
AU (1) AU729038B2 (fr)
CA (1) CA2290824A1 (fr)
GB (2) GB9710800D0 (fr)
WO (1) WO1998052564A1 (fr)
ZA (1) ZA984266B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4546643B2 (ja) * 1997-12-08 2010-09-15 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 酸不安定な活性化合物を含有する新規の坐剤形
FR2774288B1 (fr) * 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
PT1187601E (pt) 1999-06-07 2005-11-30 Altana Pharma Ag Nova forma de preparacao e a administracao compreendendo um inibidor da bomba de protoes instavel em meio acido
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2168043B1 (es) 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
JP4081273B2 (ja) 1999-10-20 2008-04-23 エーザイ・アール・アンド・ディー・マネジメント株式会社 ベンズイミダゾール系化合物安定化方法
AR021347A1 (es) 1999-10-20 2002-07-17 Cipla Ltd Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma
AU2127200A (en) * 1999-11-02 2001-05-14 Cipla Limited A pharmaceutical composition containing bisphosphonic acid(s) or salt(s) thereofand a process of preparing thereof
DE19959419A1 (de) * 1999-12-09 2001-06-21 Ratiopharm Gmbh Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
EP1605919A1 (fr) * 2003-02-28 2005-12-21 Ranbaxy Laboratories, Ltd. Compositions pharmaceutiques stables de rabeprazole et leurs procedes de fabrication
WO2005027876A1 (fr) * 2003-08-28 2005-03-31 Ranbaxy Laboratories Limited Compositions pharmaceutiques de benzimidazole et leurs procedes de preparation
WO2005032554A1 (fr) * 2003-10-03 2005-04-14 Astron Research Pvt. Ltd Nouveau systeme d'administration transmucosale
CA2565083C (fr) 2004-05-07 2014-07-08 Altana Pharma Ag Nouvelle forme posologique pharmaceutique et procede de fabrication
WO2006011159A2 (fr) * 2004-06-21 2006-02-02 Torrent Pharmaceuticals Limited Composition pharmaceutique stabilisee contenant du sodium de rabeprazole presentant une biodisponibilite amelioree
ITMI20062290A1 (it) * 2006-11-28 2008-05-29 Monteres S R L Compresse stabili allo stoccaggio a base di derivati del benzimidazolo rivestite con film gastro-resistente
CN101822671A (zh) * 2009-03-06 2010-09-08 信谊药厂 雷贝拉唑组合物及其制备方法
CN103202818A (zh) * 2012-01-15 2013-07-17 山东新时代药业有限公司 一种含有右旋雷贝拉唑或其可药用盐的肠溶片剂及其制备方法
CN102772387B (zh) * 2012-08-09 2014-02-12 广东帅广医药有限公司 兰索拉唑组合物肠溶胶囊及其制备方法
EP3292862A1 (fr) 2016-09-07 2018-03-14 Sandoz Ag Formulations d'oméprazole

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920219A (ja) * 1982-07-26 1984-02-01 Shin Etsu Chem Co Ltd 腸溶性コ−テイング製剤の製造方法
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
JPH0768125B2 (ja) * 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
DE69631981T2 (de) * 1995-09-21 2005-04-14 Pharma Pass Ii Llc, Irvine Lansoprazolhaltige Arzneizusammensetzung und Herstellungsverfahren

Also Published As

Publication number Publication date
AU7539098A (en) 1998-12-11
GB2343117A (en) 2000-05-03
GB9927132D0 (en) 2000-01-12
ZA984266B (en) 1999-01-20
WO1998052564A1 (fr) 1998-11-26
GB2343117B (en) 2001-07-25
GB9710800D0 (en) 1997-07-23
AU729038B2 (en) 2001-01-25
EP0983067A1 (fr) 2000-03-08

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead