EP1605919A1 - Compositions pharmaceutiques stables de rabeprazole et leurs procedes de fabrication - Google Patents

Compositions pharmaceutiques stables de rabeprazole et leurs procedes de fabrication

Info

Publication number
EP1605919A1
EP1605919A1 EP04715973A EP04715973A EP1605919A1 EP 1605919 A1 EP1605919 A1 EP 1605919A1 EP 04715973 A EP04715973 A EP 04715973A EP 04715973 A EP04715973 A EP 04715973A EP 1605919 A1 EP1605919 A1 EP 1605919A1
Authority
EP
European Patent Office
Prior art keywords
core
pharmaceutical composition
stable pharmaceutical
composition according
rabeprazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04715973A
Other languages
German (de)
English (en)
Inventor
Romi Barat Singh
Pananchukunnath Manoj Kumar
Vishnubhotla Nagaprasad
Rajiv Malik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of EP1605919A1 publication Critical patent/EP1605919A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention porte sur des compositions pharmaceutiques stables de rabeprazole et leurs procédés de fabrication. La composition pharmaceutique stable comprend un noyau et le noyau contient du rabeprazole et au moins 10 % en p/p d'hydroxypropylcellulose à faible viscosité.
EP04715973A 2003-02-28 2004-03-01 Compositions pharmaceutiques stables de rabeprazole et leurs procedes de fabrication Withdrawn EP1605919A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
INDE02032003 2003-02-28
IN203DE2003 2003-02-28
PCT/IB2004/000536 WO2004075881A1 (fr) 2003-02-28 2004-03-01 Compositions pharmaceutiques stables de rabeprazole et leurs procedes de fabrication

Publications (1)

Publication Number Publication Date
EP1605919A1 true EP1605919A1 (fr) 2005-12-21

Family

ID=32922929

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04715973A Withdrawn EP1605919A1 (fr) 2003-02-28 2004-03-01 Compositions pharmaceutiques stables de rabeprazole et leurs procedes de fabrication

Country Status (4)

Country Link
EP (1) EP1605919A1 (fr)
AU (1) AU2004216405A1 (fr)
CA (1) CA2517289A1 (fr)
WO (1) WO2004075881A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006105798A2 (fr) * 2005-07-11 2006-10-12 Nycomed Danmark Aps Formulation de benzimidazole
EP1872778A1 (fr) * 2006-06-29 2008-01-02 LEK Pharmaceuticals D.D. Préparation pharmaceutique stable contenant du rabéprazole sodique
JP5228359B2 (ja) * 2007-04-12 2013-07-03 ニプロ株式会社 主薬粒子及びその製造方法ならびに口腔内崩壊錠
CN105434398B (zh) * 2015-12-18 2018-09-18 康普药业股份有限公司 一种雷贝拉唑肠溶微丸及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69424487T2 (de) * 1993-09-09 2001-01-18 Takeda Chemical Industries Ltd Formulierung enthaltend einen antibakteriellen und einen Antiulcus Wirkstoff
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
EP1004305B1 (fr) * 1998-04-20 2011-09-28 Eisai R&D Management Co., Ltd. Compositions stabilisees contenant des composes du type benzimidazole
WO1999059544A2 (fr) * 1998-05-18 1999-11-25 Takeda Chemical Industries, Ltd. Comprimes se desintegrant dans la bouche
SE9902386D0 (sv) * 1999-06-22 1999-06-22 Astra Ab New formulation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2004075881A1 *

Also Published As

Publication number Publication date
WO2004075881A1 (fr) 2004-09-10
AU2004216405A1 (en) 2004-09-10
CA2517289A1 (fr) 2004-09-10

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Legal Events

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