CA2281877C - Psca: prostate stem cell antigen - Google Patents
Psca: prostate stem cell antigen Download PDFInfo
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- CA2281877C CA2281877C CA002281877A CA2281877A CA2281877C CA 2281877 C CA2281877 C CA 2281877C CA 002281877 A CA002281877 A CA 002281877A CA 2281877 A CA2281877 A CA 2281877A CA 2281877 C CA2281877 C CA 2281877C
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- BGRJTUBHPOOWDU-UHFFFAOYSA-N sulpiride Chemical compound CCN1CCCC1CNC(=O)C1=CC(S(N)(=O)=O)=CC=C1OC BGRJTUBHPOOWDU-UHFFFAOYSA-N 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
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- 229910052623 talc Inorganic materials 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
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- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 238000005382 thermal cycling Methods 0.000 description 1
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- 102000035160 transmembrane proteins Human genes 0.000 description 1
- 238000010323 transrectal needle biopsy Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
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- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81427997A | 1997-03-10 | 1997-03-10 | |
| US7114198P | 1998-01-12 | 1998-01-12 | |
| US7467598P | 1998-02-13 | 1998-02-13 | |
| US08/814,279 | 1998-02-13 | ||
| US60/074,675 | 1998-02-13 | ||
| US60/071,141 | 1998-02-13 | ||
| PCT/US1998/004665 WO1998040403A1 (en) | 1997-03-10 | 1998-03-10 | Psca: prostate stem cell antigen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2281877A1 CA2281877A1 (en) | 1998-09-17 |
| CA2281877C true CA2281877C (en) | 2010-01-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002281877A Expired - Lifetime CA2281877C (en) | 1997-03-10 | 1998-03-10 | Psca: prostate stem cell antigen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6267960B1 (enExample) |
| EP (3) | EP0981541B1 (enExample) |
| JP (3) | JP4404381B2 (enExample) |
| AT (1) | ATE268340T1 (enExample) |
| AU (1) | AU739407C (enExample) |
| CA (1) | CA2281877C (enExample) |
| DE (1) | DE69824287T2 (enExample) |
| ES (1) | ES2221982T3 (enExample) |
| NZ (1) | NZ337413A (enExample) |
| WO (1) | WO1998040403A1 (enExample) |
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| AU771026B2 (en) * | 1998-03-10 | 2004-03-11 | Regents Of The University Of California, The | PSCA: prostate stem cell antigen and uses thereof |
| US6541212B2 (en) * | 1997-03-10 | 2003-04-01 | The Regents Of The University Of California | Methods for detecting prostate stem cell antigen protein |
| AU2004200093B8 (en) * | 1997-03-10 | 2008-05-29 | The Regents Of The University Of California | "PSCA: Prostate Stem Cell Antigen and uses thereof" |
| US20080318254A9 (en) * | 1997-03-10 | 2008-12-25 | The Regents Of The University Of California | PSCA antibodies and hybridomas producing them |
| US6261791B1 (en) * | 1997-03-10 | 2001-07-17 | The Regents Of The University Of California | Method for diagnosing cancer using specific PSCA antibodies |
| WO1998051805A1 (en) * | 1997-05-15 | 1998-11-19 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the prostate |
| ATE458049T1 (de) | 1998-09-30 | 2010-03-15 | Agensys Inc | In prostatakrebs exprimiertes gen |
| US6824780B1 (en) * | 1999-10-29 | 2004-11-30 | Genentech, Inc. | Anti-tumor antibody compositions and methods of use |
| ES2309012T3 (es) * | 1999-10-29 | 2008-12-16 | Genentech, Inc. | Composiciones del anticuerpo anti-psca y a sus procedimientos contra celulas cancerigenas que expresen psca. |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| US6632620B1 (en) | 2000-06-22 | 2003-10-14 | Andrew N. Makarovskiy | Compositions for identification and isolation of stem cells |
| EP2319524B1 (en) * | 2003-05-30 | 2013-08-21 | Agensys, Inc. | Prostate stem cell antigen (PSCA) variants and subsequences thereof |
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| JP2007527699A (ja) * | 2003-06-26 | 2007-10-04 | エグゾニ・テラピューティック・ソシエテ・アノニム | 前立腺特異的遺伝子、ならびにその前立腺癌治療および診断のための標的としての使用 |
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| KR101282396B1 (ko) * | 2004-05-28 | 2013-07-04 | 어젠시스 인코포레이티드 | Psca 단백질에 결합하는 암 진단용 항체 |
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| TW202432187A (zh) | 2022-12-23 | 2024-08-16 | 美商建南德克公司 | 小腦蛋白降解劑結合物及其用途 |
| WO2024220546A2 (en) | 2023-04-17 | 2024-10-24 | Peak Bio, Inc. | Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates |
| USD1094985S1 (en) * | 2024-09-17 | 2025-09-30 | Skechers U.S.A., Inc. Ii | Outsole bottom |
Family Cites Families (5)
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|---|---|---|---|---|
| DE3684578D1 (de) * | 1985-12-17 | 1992-04-30 | Eastern Virginia Medical Autho | Monoklonale antikoerper mit bindungsspezifitaet fuer menschliche prostatatumorantigene und methoden fuer ihre verwendung. |
| CA2222231A1 (en) * | 1995-06-07 | 1996-12-19 | Imclone Systems Incorporated | Antibody and antibody fragments for inhibiting the growth of tumors |
| US5856136A (en) * | 1996-07-03 | 1999-01-05 | Incyte Pharmaceuticals, Inc. | Human stem cell antigens |
| WO1998051805A1 (en) * | 1997-05-15 | 1998-11-19 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the prostate |
| WO1998051824A1 (en) * | 1997-05-15 | 1998-11-19 | Abbott Laboratories | Reagents and methods useful for detecting disease of the urinary tract |
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1998
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- 1998-03-10 AU AU65481/98A patent/AU739407C/en not_active Expired
- 1998-03-10 EP EP98911548A patent/EP0981541B1/en not_active Expired - Lifetime
- 1998-03-10 EP EP04012820.9A patent/EP1514876B1/en not_active Expired - Lifetime
- 1998-03-10 WO PCT/US1998/004665 patent/WO1998040403A1/en not_active Ceased
- 1998-03-10 AT AT98911548T patent/ATE268340T1/de active
- 1998-03-10 US US09/038,261 patent/US6267960B1/en not_active Expired - Lifetime
- 1998-03-10 JP JP53971398A patent/JP4404381B2/ja not_active Expired - Lifetime
- 1998-03-10 CA CA002281877A patent/CA2281877C/en not_active Expired - Lifetime
- 1998-03-10 EP EP10009651.0A patent/EP2343085B1/en not_active Expired - Lifetime
- 1998-03-10 DE DE69824287T patent/DE69824287T2/de not_active Expired - Lifetime
- 1998-03-10 ES ES98911548T patent/ES2221982T3/es not_active Expired - Lifetime
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2007
- 2007-12-19 JP JP2007328082A patent/JP4615007B2/ja not_active Expired - Lifetime
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2009
- 2009-11-09 JP JP2009256004A patent/JP2010029209A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1514876B1 (en) | 2013-05-08 |
| EP2343085A3 (en) | 2011-10-26 |
| EP0981541A1 (en) | 2000-03-01 |
| AU739407C (en) | 2002-08-08 |
| DE69824287D1 (de) | 2004-07-08 |
| ES2221982T3 (es) | 2005-01-16 |
| EP2343085B1 (en) | 2014-12-10 |
| EP0981541B1 (en) | 2004-06-02 |
| AU6548198A (en) | 1998-09-29 |
| JP2010029209A (ja) | 2010-02-12 |
| JP2008133287A (ja) | 2008-06-12 |
| ATE268340T1 (de) | 2004-06-15 |
| US6267960B1 (en) | 2001-07-31 |
| AU739407B2 (en) | 2001-10-11 |
| CA2281877A1 (en) | 1998-09-17 |
| EP0981541A4 (en) | 2000-03-29 |
| DE69824287T2 (de) | 2005-06-16 |
| EP1514876A3 (en) | 2007-06-20 |
| WO1998040403A1 (en) | 1998-09-17 |
| JP2002511740A (ja) | 2002-04-16 |
| JP4615007B2 (ja) | 2011-01-19 |
| NZ337413A (en) | 2003-02-28 |
| EP2343085A2 (en) | 2011-07-13 |
| JP4404381B2 (ja) | 2010-01-27 |
| EP1514876A2 (en) | 2005-03-16 |
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