CA2270478A1 - N-(imidazolylbutyl) benzenesulphonamide derivatives, their preparation and therapeutic application - Google Patents
N-(imidazolylbutyl) benzenesulphonamide derivatives, their preparation and therapeutic application Download PDFInfo
- Publication number
- CA2270478A1 CA2270478A1 CA002270478A CA2270478A CA2270478A1 CA 2270478 A1 CA2270478 A1 CA 2270478A1 CA 002270478 A CA002270478 A CA 002270478A CA 2270478 A CA2270478 A CA 2270478A CA 2270478 A1 CA2270478 A1 CA 2270478A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- formula
- alkyl
- compound
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9614309A FR2756285B1 (fr) | 1996-11-22 | 1996-11-22 | Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique |
| FR96/14309 | 1996-11-22 | ||
| PCT/FR1997/002079 WO1998022443A1 (fr) | 1996-11-22 | 1997-11-19 | Derives de n-(imidazolylbutyle) benzenesulfonamide ayant une activite antithrombotique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2270478A1 true CA2270478A1 (en) | 1998-05-28 |
Family
ID=9497920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002270478A Abandoned CA2270478A1 (en) | 1996-11-22 | 1997-11-19 | N-(imidazolylbutyl) benzenesulphonamide derivatives, their preparation and therapeutic application |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0946517A1 (bg) |
| JP (1) | JP2001504128A (bg) |
| KR (1) | KR20000069063A (bg) |
| CN (1) | CN1238765A (bg) |
| AR (1) | AR009627A1 (bg) |
| AU (1) | AU5226498A (bg) |
| BG (1) | BG103414A (bg) |
| BR (1) | BR9713291A (bg) |
| CA (1) | CA2270478A1 (bg) |
| CO (1) | CO4910158A1 (bg) |
| CZ (1) | CZ178299A3 (bg) |
| EE (1) | EE9900201A (bg) |
| FR (1) | FR2756285B1 (bg) |
| HU (1) | HUP9904599A2 (bg) |
| IL (1) | IL129546A0 (bg) |
| NO (1) | NO992436L (bg) |
| SK (1) | SK66799A3 (bg) |
| TR (1) | TR199901143T2 (bg) |
| WO (1) | WO1998022443A1 (bg) |
| ZA (1) | ZA9710515B (bg) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2783521B1 (fr) * | 1998-09-18 | 2002-04-26 | Synthelabo | Derives de n-(arginyl) benzenesulfonamide, leur preparation et leur application en therapeutique |
| FR2806722B1 (fr) * | 2000-03-23 | 2002-05-17 | Sanofi Synthelabo | Derives de n-(heterocyclylbutyl) benzene-ou pyridine sulfonamide, leur preparation et leur application en therapeutique |
| CN107207403A (zh) | 2014-09-29 | 2017-09-26 | 塞尔利克斯生物私人有限公司 | 用于治疗多发性硬化的组合物和方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2689130B1 (fr) * | 1992-03-30 | 1994-05-27 | Synthelabo | Derives de 1-[2 (arylsulfonylamino)ethyl-1-oxo] piperidine, leur preparation et leur application en therapeutique. |
| FR2710066B1 (fr) * | 1993-09-14 | 1995-10-20 | Synthelabo | Dérivés de 1-[2-amino-5-[1-(triphénylméthyl-1H-imidazol-4-yl]-1-oxopentyl]piperidine, leur préparation et leur utilisation comme intermédiaires de synthèse. |
| FR2727410B1 (fr) * | 1994-11-25 | 1996-12-20 | Synthelabo | Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese |
| FR2728570B1 (fr) * | 1994-12-23 | 1997-04-11 | Synthelabo | Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique |
| DE19548797A1 (de) * | 1995-12-27 | 1997-07-03 | Thomae Gmbh Dr K | Substituierte 2-Amino-imidazole, ihre Herstellung und ihre Verwendung als Arzneimittel |
-
1996
- 1996-11-22 FR FR9614309A patent/FR2756285B1/fr not_active Expired - Fee Related
-
1997
- 1997-11-19 CN CN97199986A patent/CN1238765A/zh active Pending
- 1997-11-19 CO CO97067574A patent/CO4910158A1/es unknown
- 1997-11-19 CA CA002270478A patent/CA2270478A1/en not_active Abandoned
- 1997-11-19 AU AU52264/98A patent/AU5226498A/en not_active Abandoned
- 1997-11-19 HU HU9904599A patent/HUP9904599A2/hu unknown
- 1997-11-19 BR BR9713291-8A patent/BR9713291A/pt not_active Application Discontinuation
- 1997-11-19 KR KR1019997004485A patent/KR20000069063A/ko not_active Application Discontinuation
- 1997-11-19 JP JP52328498A patent/JP2001504128A/ja active Pending
- 1997-11-19 TR TR1999/01143T patent/TR199901143T2/xx unknown
- 1997-11-19 WO PCT/FR1997/002079 patent/WO1998022443A1/fr not_active Application Discontinuation
- 1997-11-19 EE EEP199900201A patent/EE9900201A/xx unknown
- 1997-11-19 CZ CZ991782A patent/CZ178299A3/cs unknown
- 1997-11-19 EP EP97947089A patent/EP0946517A1/fr not_active Ceased
- 1997-11-19 IL IL12954697A patent/IL129546A0/xx unknown
- 1997-11-19 SK SK667-99A patent/SK66799A3/sk unknown
- 1997-11-21 AR ARP970105455A patent/AR009627A1/es unknown
- 1997-11-21 ZA ZA9710515A patent/ZA9710515B/xx unknown
-
1999
- 1999-05-19 BG BG103414A patent/BG103414A/bg unknown
- 1999-05-20 NO NO992436A patent/NO992436L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SK66799A3 (en) | 2000-02-14 |
| BG103414A (bg) | 2000-01-31 |
| HUP9904599A2 (hu) | 2000-06-28 |
| JP2001504128A (ja) | 2001-03-27 |
| WO1998022443A1 (fr) | 1998-05-28 |
| NO992436D0 (no) | 1999-05-20 |
| AU5226498A (en) | 1998-06-10 |
| CZ178299A3 (cs) | 1999-08-11 |
| FR2756285B1 (fr) | 1998-12-18 |
| IL129546A0 (en) | 2000-02-29 |
| BR9713291A (pt) | 1999-10-26 |
| EP0946517A1 (fr) | 1999-10-06 |
| AR009627A1 (es) | 2000-04-26 |
| EE9900201A (et) | 1999-12-15 |
| ZA9710515B (en) | 1998-06-10 |
| TR199901143T2 (xx) | 1999-08-23 |
| CN1238765A (zh) | 1999-12-15 |
| FR2756285A1 (fr) | 1998-05-29 |
| KR20000069063A (ko) | 2000-11-25 |
| CO4910158A1 (es) | 2000-04-24 |
| NO992436L (no) | 1999-07-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |