CA2256124C - Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans - Google Patents
Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans Download PDFInfo
- Publication number
- CA2256124C CA2256124C CA2256124A CA2256124A CA2256124C CA 2256124 C CA2256124 C CA 2256124C CA 2256124 A CA2256124 A CA 2256124A CA 2256124 A CA2256124 A CA 2256124A CA 2256124 C CA2256124 C CA 2256124C
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- Prior art keywords
- protein
- leishmaniasis
- seq
- amino acid
- proteins
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- Expired - Lifetime
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- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 206010048282 zoonosis Diseases 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (37)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2256124A CA2256124C (en) | 1998-12-23 | 1998-12-23 | Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans |
| SI9931029T SI1624063T1 (sl) | 1998-12-23 | 1999-12-23 | Himerni gen, ki kodira antigenske determinante štirih beljakovin iz L. infantuma |
| JP2000591189A JP4883839B2 (ja) | 1998-12-23 | 1999-12-23 | エル．インファンタム（Ｌ．ｉｎｆａｎｔｕｍ）の４つのタンパク質の抗原決定基をコードするキメラ遺伝子 |
| IL14395699A IL143956A0 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of l.infantum |
| HU0104743A HUP0104743A3 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of l. infantum |
| PT99967987T PT1141305E (pt) | 1998-12-23 | 1999-12-23 | Gene quimerico formado pelas sequencias de adn que codifica os determinantes antigenicos de quatro proteinas de l. infantum |
| EP05109393A EP1624063B1 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of L. infantum |
| TR2001/02655T TR200102655T2 (tr) | 1998-12-23 | 1999-12-23 | Dört L. infantum proteininin antijen belirleyicilerini kodlayan kimerik gen. |
| YUP-516/01A RS50013B (sr) | 1998-12-23 | 1999-12-23 | Himerni gen koji kodira antigene determinante četiri proteina l.infantum |
| CZ20012360A CZ20012360A3 (cs) | 1998-12-23 | 1999-12-23 | Farmaceutický prostředek, vakcína, protein a způsob prevence nebo léčby |
| SI9930918T SI1141305T1 (sl) | 1998-12-23 | 1999-12-23 | Himerni gen, ki kodira antigenske determinante stirih proteinov L. Infantum |
| PT05109393T PT1624063E (pt) | 1998-12-23 | 1999-12-23 | Gene quimérico que codifica os determinantes antigénicos das quatro proteínas de l. infantum |
| AT99967987T ATE327332T1 (de) | 1998-12-23 | 1999-12-23 | Chimärisches gen, dass für die antigenischen determinanten von vier protein aus l. infantum kodiert |
| AT05109393T ATE429498T1 (de) | 1998-12-23 | 1999-12-23 | Chimärisches gen, dass für die antigenischen determinanten von vier proteinen aus l. infantum kodiert |
| MXPA01006548A MXPA01006548A (es) | 1998-12-23 | 1999-12-23 | Gen de quimerico que codifica los determinantes antigenicos de cuatro proteinas de l. infantum. |
| EP99967987A EP1141305B1 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of l. infantum |
| PCT/EP1999/010441 WO2000039298A1 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of l. infantum |
| ES05109393T ES2326174T3 (es) | 1998-12-23 | 1999-12-23 | Gen quimerico que codifica los determinantes antigenicos de cuatro proteinas de l. infantum. |
| BRPI9916549A BRPI9916549B8 (pt) | 1998-12-23 | 1999-12-23 | Composição farmacêutica, proteína, polinucleotídeo |
| BRPI9917863A BRPI9917863B8 (pt) | 1998-12-23 | 1999-12-23 | composição farmacêutica que é uma vacina |
| CNB998163066A CN1158387C (zh) | 1998-12-23 | 1999-12-23 | 编码l.infantum的四种蛋白质的抗原决定簇的嵌合基因 |
| DK99967987T DK1141305T3 (da) | 1998-12-23 | 1999-12-23 | Kimært gen som koder for de antigene determinanter af fire proteiner af L. infantum |
| DE69931518T DE69931518T2 (de) | 1998-12-23 | 1999-12-23 | Chimäres Gen, das für die antigenischen Determinaten von vier Proteinen aus L. Infantum kodiert |
| ES99967987T ES2273519T3 (es) | 1998-12-23 | 1999-12-23 | Gen quimerico que codifica los determinantes antigenicos de cuatro proteinas de l. infantum. |
| DE69940793T DE69940793D1 (de) | 1998-12-23 | 1999-12-23 | Chimärisches Gen, dass für die antigenischen Determinanten von vier Proteinen aus L. Infantum kodiert |
| AU24342/00A AU759316B2 (en) | 1998-12-23 | 1999-12-23 | Chimeric gene encoding the antigenic determinants of four proteins of L. infantum |
| IL143956A IL143956A (en) | 1998-12-23 | 2001-06-24 | Chimeric polypeptide having the antigenic determinants of four proteins of l. infantum, polynucleotides encoding same, methods of production and use thereof in therapeutic compositions |
| ZA200105994A ZA200105994B (en) | 1998-12-23 | 2001-07-20 | Chimeric gene encoding the antigenic determinants of four proteins of L. infantum. |
| BG105725A BG65569B1 (bg) | 1998-12-23 | 2001-07-23 | Химерен ген кодиращ антигенни детерминанти на четири протеина на l. infantum |
| HR20010554A HRP20010554A2 (en) | 1998-12-23 | 2001-07-23 | Chimeric gene encoding the antigenic determinants of four proteins of l. infantum |
| CY20061101190T CY1105331T1 (el) | 1998-12-23 | 2006-08-24 | Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
| CY20091100739T CY1109221T1 (el) | 1998-12-23 | 2009-07-14 | Χιμαιρικο γονιδιο που κωδικοποιει τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
| NL300830C NL300830I2 (nl) | 1998-12-23 | 2016-09-22 | Protein Q, een recombinant chimeer eiwit, bestaande uit vijf antigenefragmenten van vier verschillende Leishmania infantum (zymodeme Mon-1) eiwitten |
| BE2016C049C BE2016C049I2 (el) | 1998-12-23 | 2016-10-06 | |
| LU93259C LU93259I2 (fr) | 1998-12-23 | 2016-10-06 | LETIFEND (Protein Q) |
| FR16C0040C FR16C0040I2 (fr) | 1998-12-23 | 2016-10-19 | Gene chimerique forme par les sequences d'adn codant pour les determinants antigeniques de quatre proteines de l. infantum |
| CY2016033C CY2016033I1 (el) | 1998-12-23 | 2016-10-20 | Χιμαιρικα γονιδια που κωδικοποιουν τους αντιγονικους καθοριστες τεσσαρων πρωτεϊνων του l. infantum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2256124A CA2256124C (en) | 1998-12-23 | 1998-12-23 | Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2256124A1 CA2256124A1 (en) | 2000-06-23 |
| CA2256124C true CA2256124C (en) | 2015-06-16 |
Family
ID=27671952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2256124A Expired - Lifetime CA2256124C (en) | 1998-12-23 | 1998-12-23 | Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP4883839B2 (el) |
| BR (1) | BRPI9917863B8 (el) |
| CA (1) | CA2256124C (el) |
| RS (1) | RS50013B (el) |
| ZA (1) | ZA200105994B (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012062861A1 (en) * | 2010-11-10 | 2012-05-18 | Laboratorios Leti, S.L. | New adjuvant |
-
1998
- 1998-12-23 CA CA2256124A patent/CA2256124C/en not_active Expired - Lifetime
-
1999
- 1999-12-23 RS YUP-516/01A patent/RS50013B/sr unknown
- 1999-12-23 JP JP2000591189A patent/JP4883839B2/ja not_active Expired - Lifetime
- 1999-12-23 BR BRPI9917863A patent/BRPI9917863B8/pt not_active IP Right Cessation
-
2001
- 2001-07-20 ZA ZA200105994A patent/ZA200105994B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002533474A (ja) | 2002-10-08 |
| BRPI9917863A2 (el) | 2010-12-21 |
| CA2256124A1 (en) | 2000-06-23 |
| ZA200105994B (en) | 2002-07-22 |
| YU51601A (sh) | 2005-07-19 |
| RS50013B (sr) | 2008-09-29 |
| BRPI9917863C1 (pt) | 2021-05-25 |
| BRPI9917863B1 (pt) | 2016-08-02 |
| BRPI9917863B8 (pt) | 2022-08-30 |
| JP4883839B2 (ja) | 2012-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20181224 |