CA2186503C - Etiquettes electrophotochimiques pour les travaux d'analyse et/ou de reference - Google Patents

Etiquettes electrophotochimiques pour les travaux d'analyse et/ou de reference Download PDF

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Publication number
CA2186503C
CA2186503C CA002186503A CA2186503A CA2186503C CA 2186503 C CA2186503 C CA 2186503C CA 002186503 A CA002186503 A CA 002186503A CA 2186503 A CA2186503 A CA 2186503A CA 2186503 C CA2186503 C CA 2186503C
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coreactant
ecl
dpas
tpra
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CA2186503A1 (fr
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Allen J. Bard
Thomas C. Richards
Jonathan K. Leland
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Bioveris Corp
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Bioveris Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Dental Preparations (AREA)

Abstract

L'invention concerne l'analyse des biomolécules par oxydation anodique de sodium 9, 10-diphénylanthracène-2-sulfonate (DPAS) et d'acide 1- et 2-thianthrènecarboxylique (1-THCOOH et 2-THCOOH) en présence de tri-n-propylamine (TPrA) comme coréactif dans une solution aqueuse. Ce procédé engendre l'électrophotochimie (ECL). Par ailleurs, la réduction cathodique de DPAS en présence de peroxydisulfate (S¿2?O¿8??2-¿) comme coréactif engendre également l'électrophotochimie dans une solution aqueuse (1:1 en volume) d'acétonitrile (MeCN). L'oxydation de la chlorpromazine (CPZ) engendre l'électrophotochimie sans l'adjonction d'un coréactif, selon un mécanisme d'"auto-annihilation" sans précédent.
CA002186503A 1995-02-09 1996-02-09 Etiquettes electrophotochimiques pour les travaux d'analyse et/ou de reference Expired - Lifetime CA2186503C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/385,864 US5786141A (en) 1994-08-26 1995-02-09 Electrogenerated chemiluminescence labels for analysis and/or referencing
US08/385,864 1995-02-09
PCT/US1996/001113 WO1996024690A1 (fr) 1995-02-09 1996-02-09 Etiquettes electrophotochimiques pour les travaux d'analyse et/ou de reference

Publications (2)

Publication Number Publication Date
CA2186503A1 CA2186503A1 (fr) 1996-08-15
CA2186503C true CA2186503C (fr) 2007-01-23

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Application Number Title Priority Date Filing Date
CA002186503A Expired - Lifetime CA2186503C (fr) 1995-02-09 1996-02-09 Etiquettes electrophotochimiques pour les travaux d'analyse et/ou de reference

Country Status (11)

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US (2) US5786141A (fr)
EP (1) EP0755458B1 (fr)
JP (1) JP3989019B2 (fr)
AT (1) ATE274601T1 (fr)
AU (1) AU709592B2 (fr)
CA (1) CA2186503C (fr)
DE (1) DE69633212T2 (fr)
DK (1) DK0755458T3 (fr)
ES (1) ES2227580T3 (fr)
PT (1) PT755458E (fr)
WO (1) WO1996024690A1 (fr)

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Publication number Publication date
JP3989019B2 (ja) 2007-10-10
US6479233B1 (en) 2002-11-12
DE69633212D1 (de) 2004-09-30
DE69633212T2 (de) 2005-09-22
DK0755458T3 (da) 2004-11-29
AU4770896A (en) 1996-08-27
CA2186503A1 (fr) 1996-08-15
EP0755458B1 (fr) 2004-08-25
EP0755458A4 (fr) 2000-07-26
ES2227580T3 (es) 2005-04-01
ATE274601T1 (de) 2004-09-15
AU709592B2 (en) 1999-09-02
PT755458E (pt) 2005-01-31
WO1996024690A1 (fr) 1996-08-15
EP0755458A1 (fr) 1997-01-29
JPH10502702A (ja) 1998-03-10
US5786141A (en) 1998-07-28

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