CA2156121C - Method of manufacturing the cycloheptimidazole derivatives - Google Patents

Method of manufacturing the cycloheptimidazole derivatives Download PDF

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Publication number
CA2156121C
CA2156121C CA002156121A CA2156121A CA2156121C CA 2156121 C CA2156121 C CA 2156121C CA 002156121 A CA002156121 A CA 002156121A CA 2156121 A CA2156121 A CA 2156121A CA 2156121 C CA2156121 C CA 2156121C
Authority
CA
Canada
Prior art keywords
compound
general formula
group
hydrogen
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002156121A
Other languages
English (en)
French (fr)
Other versions
CA2156121A1 (en
Inventor
Tsuyoshi Tomiyama
Akira Tomiyama
Takashi Yanagisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kotobuki Seiyaku Co Ltd
Original Assignee
Kotobuki Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Seiyaku Co Ltd filed Critical Kotobuki Seiyaku Co Ltd
Publication of CA2156121A1 publication Critical patent/CA2156121A1/en
Application granted granted Critical
Publication of CA2156121C publication Critical patent/CA2156121C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002156121A 1994-09-05 1995-08-15 Method of manufacturing the cycloheptimidazole derivatives Expired - Fee Related CA2156121C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP210867/94 1994-09-05
JP21086794A JP4316686B2 (ja) 1994-09-05 1994-09-05 シクロヘプトイミダゾール誘導体

Publications (2)

Publication Number Publication Date
CA2156121A1 CA2156121A1 (en) 1996-03-06
CA2156121C true CA2156121C (en) 2006-03-28

Family

ID=16596423

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002156121A Expired - Fee Related CA2156121C (en) 1994-09-05 1995-08-15 Method of manufacturing the cycloheptimidazole derivatives

Country Status (7)

Country Link
JP (1) JP4316686B2 (no)
CN (1) CN1061655C (no)
CA (1) CA2156121C (no)
CH (1) CH689511A5 (no)
HU (1) HU226806B1 (no)
NO (1) NO308358B1 (no)
TW (1) TW408113B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638937B2 (en) 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
CN115093372B (zh) * 2022-06-16 2023-05-30 安徽工程大学 一种咪唑衍生物的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2707390B2 (ja) * 1992-05-22 1998-01-28 壽製薬株式会社 シクロヘプトイミダゾ−ル誘導体及びその製造方法並びにこれを含有する薬剤

Also Published As

Publication number Publication date
CA2156121A1 (en) 1996-03-06
JP4316686B2 (ja) 2009-08-19
NO953459D0 (no) 1995-09-04
NO308358B1 (no) 2000-09-04
HU9502172D0 (en) 1995-09-28
CN1061655C (zh) 2001-02-07
HU226806B1 (en) 2009-10-28
TW408113B (en) 2000-10-11
CH689511A5 (de) 1999-05-31
HUT73184A (en) 1996-06-28
JPH0873454A (ja) 1996-03-19
NO953459L (no) 1996-03-06
CN1127752A (zh) 1996-07-31

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Effective date: 20130815