CA2136211A1 - Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent - Google Patents

Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent

Info

Publication number
CA2136211A1
CA2136211A1 CA002136211A CA2136211A CA2136211A1 CA 2136211 A1 CA2136211 A1 CA 2136211A1 CA 002136211 A CA002136211 A CA 002136211A CA 2136211 A CA2136211 A CA 2136211A CA 2136211 A1 CA2136211 A1 CA 2136211A1
Authority
CA
Canada
Prior art keywords
carbon atoms
radical
alkyl
atoms
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002136211A
Other languages
English (en)
French (fr)
Inventor
Jean-Dominique Bourzat
Alain Commercon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2136211A1 publication Critical patent/CA2136211A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
CA002136211A 1992-05-21 1993-05-18 Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent Abandoned CA2136211A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR92/06177 1992-05-21
FR9206177A FR2691460B1 (fr) 1992-05-21 1992-05-21 Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent.

Publications (1)

Publication Number Publication Date
CA2136211A1 true CA2136211A1 (fr) 1993-11-25

Family

ID=9430017

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002136211A Abandoned CA2136211A1 (fr) 1992-05-21 1993-05-18 Nouveaux derives du taxane, leur preparation et les compositions qui les contiennent

Country Status (13)

Country Link
EP (1) EP0641334A1 (ko)
JP (1) JPH07506586A (ko)
KR (1) KR950701629A (ko)
AU (1) AU4075893A (ko)
CA (1) CA2136211A1 (ko)
CZ (1) CZ285294A3 (ko)
FI (1) FI945439A (ko)
FR (1) FR2691460B1 (ko)
MX (1) MX9302915A (ko)
SK (1) SK139994A3 (ko)
TW (1) TW227560B (ko)
WO (1) WO1993023389A1 (ko)
ZA (1) ZA933462B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2368151A1 (en) 2000-02-02 2001-08-09 Florida State University Research Foundation, Inc. C10 carbonate substituted taxanes as antitumor agents
JP2003522173A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのｃ１０カルバモイルオキシ置換タキサン
HN2005000054A (es) 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
JP2011517455A (ja) 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン
CN103983627A (zh) * 2008-06-17 2014-08-13 韩国巴斯德研究所 作为抗结核病药的吡啶并嘧啶化合物
CA2798180A1 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN105294610B (zh) * 2015-07-16 2017-10-31 中国科学院上海药物研究所 7‑epi‑紫杉烷类化合物的制备方法
CN107021943B (zh) * 2016-02-02 2020-12-29 中国科学院上海药物研究所 一类7-epi-巴卡亭III衍生物，及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206221A (en) * 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
FR2658513B1 (fr) * 1990-02-21 1994-02-04 Rhone Poulenc Sante Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).

Also Published As

Publication number Publication date
WO1993023389A1 (fr) 1993-11-25
FR2691460A1 (fr) 1993-11-26
ZA933462B (en) 1993-12-14
FI945439A0 (fi) 1994-11-18
EP0641334A1 (fr) 1995-03-08
TW227560B (ko) 1994-08-01
FI945439A (fi) 1994-11-18
SK139994A3 (en) 1995-07-11
FR2691460B1 (fr) 1994-07-22
KR950701629A (ko) 1995-04-28
JPH07506586A (ja) 1995-07-20
AU4075893A (en) 1993-12-13
MX9302915A (es) 1993-11-01
CZ285294A3 (en) 1995-04-12

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Legal Events

Date Code Title Description
FZDE Dead