CA2131101A1 - Compositions ophtalmiques topiques qui renferment une combinaison d'antagonistes du calcium comprenant des agents reconnus efficaces contre le glaucome - Google Patents
Compositions ophtalmiques topiques qui renferment une combinaison d'antagonistes du calcium comprenant des agents reconnus efficaces contre le glaucomeInfo
- Publication number
- CA2131101A1 CA2131101A1 CA002131101A CA2131101A CA2131101A1 CA 2131101 A1 CA2131101 A1 CA 2131101A1 CA 002131101 A CA002131101 A CA 002131101A CA 2131101 A CA2131101 A CA 2131101A CA 2131101 A1 CA2131101 A1 CA 2131101A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- compound
- intraocular pressure
- lowers
- calcium antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88232892A | 1992-05-13 | 1992-05-13 | |
US882,328 | 1992-05-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2131101A1 true CA2131101A1 (fr) | 1993-11-25 |
Family
ID=25380354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002131101A Abandoned CA2131101A1 (fr) | 1992-05-13 | 1993-05-12 | Compositions ophtalmiques topiques qui renferment une combinaison d'antagonistes du calcium comprenant des agents reconnus efficaces contre le glaucome |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0639986A1 (fr) |
JP (1) | JPH07508030A (fr) |
AU (1) | AU4246793A (fr) |
CA (1) | CA2131101A1 (fr) |
WO (1) | WO1993023082A1 (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2686879B1 (fr) * | 1992-02-05 | 1994-03-18 | Adir Cie | Nouveaux composes de 1,4-dihydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant. |
US5922773A (en) * | 1992-12-04 | 1999-07-13 | The Children's Medical Center Corp. | Glaucoma treatment |
US5756502A (en) * | 1994-08-08 | 1998-05-26 | Warner-Lambert Company | Quinazolinone derivatives as cholyecystokinin (CCK) ligands |
DE4430128A1 (de) * | 1994-08-25 | 1996-02-29 | Hoechst Ag | Kombinationspräparat mit immunsuppressiven, kardiovaskulären und cerebralen Wirkungen |
US5733938A (en) * | 1994-09-09 | 1998-03-31 | Allergan | Combination of levobunolol and dipivefrin for topical ophthalmic use |
US5780450A (en) * | 1995-11-21 | 1998-07-14 | Alcon Laboratories, Inc. | Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage |
ATE289815T1 (de) | 1995-12-21 | 2005-03-15 | Alcon Lab Inc | Verwendung von substituierten isochinolinsulfonyl-verbindungen zur herstellung eines medikaments für die behandlung von glaukom und okularer ischämie |
US6225327B1 (en) | 1996-04-18 | 2001-05-01 | Alcon Laboratories, Inc. | Compounds which inhibit human conjunctival mast cell degranulation for treating ocular allergic-type complications |
JP3541389B2 (ja) | 1996-04-26 | 2004-07-07 | 藤沢薬品工業株式会社 | ジヒドロピリジン化合物を含有する眼組織末梢循環改善剤 |
WO1997045118A1 (fr) * | 1996-05-27 | 1997-12-04 | Otsuka Pharmaceutical Co., Ltd. | Agents ameliorant le flux sanguin ophtalmovasculaire et agents protecteurs des papilles optiques |
DE69739190D1 (de) * | 1996-10-28 | 2009-02-12 | Senju Pharma Co | Arzneimittel zur behandlung von oculären kreislauferkrankungen |
IT1295423B1 (it) * | 1997-10-10 | 1999-05-12 | Medivis S R L | Uso della flunarizina nella terapia topica del glaucoma |
ES2224597T3 (es) | 1998-01-29 | 2005-03-01 | Akzo Nobel N.V. | Agentes que mejoran la circulacion optica papilar. |
AU3328600A (en) * | 1999-03-25 | 2000-10-16 | Santen Pharmaceutical Co. Ltd. | Ocular tension-lowering agents |
US6482854B1 (en) | 1999-03-25 | 2002-11-19 | Massachusetts Eye And Ear Infirmary | Glaucoma treatment |
DE60014629T2 (de) * | 1999-04-14 | 2006-02-23 | Senju Pharmaceutical Co., Ltd. | 1,4-dihydropyridinderivate als Inhibitoren einer Sehunterfunktion, hervorgerufen durch eine Sehnervzellenverletzung, die durch andere Faktoren als optischen Durchblutungstörungen induziert wird. |
US6462066B2 (en) | 1999-12-02 | 2002-10-08 | University Of South Florida | Method and composition for treatment of ischemic neuronal reperfusion injury |
ATE266666T1 (de) * | 2000-03-23 | 2004-05-15 | Ortho Mcneil Pharm Inc | Thiepino(3,2-b)dihydropyridine und relatierte zusammensetzungen und verfahren |
US6562824B2 (en) * | 2000-05-30 | 2003-05-13 | Ortho-Mcneil Pharmaceutical, Inc. | Dihydropyridine soft drugs, and related compositions and methods |
US20040242565A1 (en) * | 2001-09-11 | 2004-12-02 | Yoshinori Toshima | Medicinal composition for prevention of or treatment for cerebrovascular disorder and cardiopathy |
TW200306839A (en) | 2002-02-06 | 2003-12-01 | Novartis Ag | Quinazolinone derivatives and their use as CB agonists |
JPWO2003082234A1 (ja) * | 2002-03-28 | 2005-07-28 | 株式会社資生堂 | フェニルアセトニトリル誘導体及びこれを含有する養毛剤、皮膚外用剤 |
EP1568382B1 (fr) | 2002-11-18 | 2013-11-06 | Santen Pharmaceutical Co., Ltd. | Medicament contre le glaucome comprenant un inhibiteur de la rho-kinase et un betabloquant |
WO2004069275A1 (fr) * | 2003-02-04 | 2004-08-19 | Mitsubishi Pharma Corporation | Medicaments ophtalmiques |
JP5576659B2 (ja) * | 2006-12-05 | 2014-08-20 | ザ ロイヤル インスティテューション フォー ジ アドバンスメント オブ ラーニング/ マギル ユニバーシティ | Trkレセプター調節因子の使用方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4911920A (en) * | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
FR2577802B1 (fr) * | 1985-02-26 | 1987-07-24 | Synthelabo | Compositions pharmaceutiques a base de betaxolol et de nifedipine |
FR2585574B1 (fr) * | 1985-07-31 | 1988-09-09 | Corbiere Jerome | Nouvelles compositions pharmaceutiques anti-glaucomateuses a base de 1,4-dihydropyridines et leur procede d'obtention |
FR2593395A1 (fr) * | 1986-01-28 | 1987-07-31 | Corbiere Jerome | Nouvelles compositions pharmaceutiques antiglaucomateuses a base de 3-acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepine-4-one ou d'un de ses sels et leur procede d'obtention |
US4981871A (en) * | 1987-05-15 | 1991-01-01 | Abelson Mark B | Treatment of ocular hypertension with class I calcium channel blocking agents |
CA2064160C (fr) * | 1991-03-27 | 1998-08-11 | Paul J. T. Missel | Emploi de polysaccharides gelifiants combines a des substrats finement divises a action de vecteur des medicaments, dans des compositions ophthalmiques a usage local |
-
1993
- 1993-05-12 CA CA002131101A patent/CA2131101A1/fr not_active Abandoned
- 1993-05-12 EP EP93911276A patent/EP0639986A1/fr not_active Withdrawn
- 1993-05-12 JP JP6503718A patent/JPH07508030A/ja active Pending
- 1993-05-12 WO PCT/US1993/004505 patent/WO1993023082A1/fr not_active Application Discontinuation
- 1993-05-12 AU AU42467/93A patent/AU4246793A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1993023082A1 (fr) | 1993-11-25 |
AU4246793A (en) | 1993-12-13 |
JPH07508030A (ja) | 1995-09-07 |
EP0639986A1 (fr) | 1995-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |