CA2112523A1 - 2-amino-6,7- dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof - Google Patents
2-amino-6,7- dihydroxy-4-thiaheptanoic acid derivatives, production and use thereofInfo
- Publication number
- CA2112523A1 CA2112523A1 CA002112523A CA2112523A CA2112523A1 CA 2112523 A1 CA2112523 A1 CA 2112523A1 CA 002112523 A CA002112523 A CA 002112523A CA 2112523 A CA2112523 A CA 2112523A CA 2112523 A1 CA2112523 A1 CA 2112523A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- gly
- glu
- amino
- bis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34906292 | 1992-12-28 | ||
| JP349062/1992 | 1992-12-28 | ||
| JP5618593 | 1993-03-16 | ||
| JP056185/1993 | 1993-03-16 | ||
| JP181735/1993 | 1993-07-22 | ||
| JP18173593 | 1993-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2112523A1 true CA2112523A1 (en) | 1994-06-29 |
Family
ID=27295829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002112523A Abandoned CA2112523A1 (en) | 1992-12-28 | 1993-12-29 | 2-amino-6,7- dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof |
Country Status (15)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002018417A1 (en) * | 2000-09-01 | 2002-03-07 | Gryphon Therapeutics, Inc. | Nucleophile-stable thioester generating compounds, methods of production and use |
| EP1382352A1 (de) * | 2002-07-19 | 2004-01-21 | GBF Gesellschaft für Biotechnologische Forschung mbH | Bisacyloxypropylcystein-Konjugate und deren Verwendung |
| DE102005024040A1 (de) * | 2005-05-25 | 2006-12-14 | Rovi Gmbh & Co. Kosmetische Rohstoffe Kg | Kosmetisches oder therapeutisches Kombinationspräparat mit Theanin |
| PT1904084E (pt) | 2005-06-13 | 2013-07-22 | Cleveland Clinic Foundation | Métodos de proteção contra apoptose mediante uso de lipopéptidos |
| CA2644552C (en) * | 2006-03-01 | 2013-05-28 | Kyoto University | Peptide lipid-containing carrier and method for introducing compound into cells using same |
| DE102009034779A1 (de) * | 2009-07-25 | 2011-02-03 | Emc Microcollections Gmbh | Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen |
| WO2011119759A1 (en) * | 2010-03-23 | 2011-09-29 | Irm Llc | Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2860893D1 (en) * | 1977-06-20 | 1981-11-05 | Ciba Geigy Ag | Lipopeptides, process for their preparation and pharmaceutical compositions containing them |
| EP0014815A3 (de) * | 1978-12-20 | 1980-10-29 | Ciba-Geigy Ag | Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen |
| DE3485094D1 (de) * | 1983-01-25 | 1991-10-31 | Ciba Geigy Ag | Neue peptidderivate. |
| DE3546150A1 (de) * | 1985-06-24 | 1987-01-22 | Hoechst Ag | Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung |
| JPH0446194A (ja) * | 1990-06-13 | 1992-02-17 | Fujisawa Pharmaceut Co Ltd | Ｗｓ１２７９ａ物質、その生産法及び用途 |
| JPH0499796A (ja) * | 1990-08-13 | 1992-03-31 | Kazuo Achinami | 新規リポペプタイド及び抗腫瘍剤 |
| EP0548024B1 (de) * | 1991-12-19 | 1997-01-08 | Ciba-Geigy Ag | Aminosulfonsäurederivate und Verfahren zu ihrer Herstellung |
-
1993
- 1993-12-21 AU AU52614/93A patent/AU666789B2/en not_active Ceased
- 1993-12-22 TW TW082110873A patent/TW264479B/zh active
- 1993-12-23 NZ NZ250588A patent/NZ250588A/en unknown
- 1993-12-24 IL IL108173A patent/IL108173A/xx unknown
- 1993-12-27 NO NO934834A patent/NO934834L/no unknown
- 1993-12-27 PH PH47555A patent/PH30687A/en unknown
- 1993-12-27 DE DE69320931T patent/DE69320931T2/de not_active Expired - Fee Related
- 1993-12-27 EP EP93120970A patent/EP0604957B1/en not_active Expired - Lifetime
- 1993-12-27 FI FI935888A patent/FI935888A7/fi not_active Application Discontinuation
- 1993-12-27 HU HU9303761A patent/HUT65865A/hu unknown
- 1993-12-27 AT AT93120970T patent/ATE170871T1/de not_active IP Right Cessation
- 1993-12-28 CN CN93121751A patent/CN1094731A/zh active Pending
- 1993-12-28 KR KR1019930030357A patent/KR940014436A/ko not_active Withdrawn
- 1993-12-28 US US08/174,374 patent/US5478808A/en not_active Expired - Fee Related
- 1993-12-29 CA CA002112523A patent/CA2112523A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1094731A (zh) | 1994-11-09 |
| US5478808A (en) | 1995-12-26 |
| IL108173A (en) | 1998-03-10 |
| HUT65865A (en) | 1994-07-28 |
| FI935888A0 (fi) | 1993-12-27 |
| KR940014436A (ko) | 1994-07-18 |
| DE69320931D1 (de) | 1998-10-15 |
| AU5261493A (en) | 1994-07-07 |
| AU666789B2 (en) | 1996-02-22 |
| NO934834D0 (no) | 1993-12-27 |
| NZ250588A (en) | 1995-03-28 |
| FI935888L (fi) | 1994-06-29 |
| EP0604957A1 (en) | 1994-07-06 |
| PH30687A (en) | 1997-09-16 |
| ATE170871T1 (de) | 1998-09-15 |
| IL108173A0 (en) | 1994-04-12 |
| DE69320931T2 (de) | 1999-05-20 |
| HU9303761D0 (en) | 1994-04-28 |
| EP0604957B1 (en) | 1998-09-09 |
| TW264479B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1995-12-01 |
| NO934834L (no) | 1994-06-29 |
| FI935888A7 (fi) | 1994-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |