CA2080555C - Bis(phenyl)ethane derivatives - Google Patents

Bis(phenyl)ethane derivatives Download PDF

Info

Publication number
CA2080555C
CA2080555C CA002080555A CA2080555A CA2080555C CA 2080555 C CA2080555 C CA 2080555C CA 002080555 A CA002080555 A CA 002080555A CA 2080555 A CA2080555 A CA 2080555A CA 2080555 C CA2080555 C CA 2080555C
Authority
CA
Canada
Prior art keywords
compound
formula
alkoxy
compounds
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002080555A
Other languages
English (en)
French (fr)
Other versions
CA2080555A1 (en
Inventor
Peter Nussbaumer
Anton Stuetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2080555A1 publication Critical patent/CA2080555A1/en
Application granted granted Critical
Publication of CA2080555C publication Critical patent/CA2080555C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • External Artificial Organs (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Paints Or Removers (AREA)
CA002080555A 1991-10-16 1992-10-14 Bis(phenyl)ethane derivatives Expired - Fee Related CA2080555C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919121943A GB9121943D0 (en) 1991-10-16 1991-10-16 Organic compounds,processes for their production and their use
GB9121943 1991-10-16

Publications (2)

Publication Number Publication Date
CA2080555A1 CA2080555A1 (en) 1993-04-17
CA2080555C true CA2080555C (en) 2003-12-30

Family

ID=10703010

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002080555A Expired - Fee Related CA2080555C (en) 1991-10-16 1992-10-14 Bis(phenyl)ethane derivatives

Country Status (27)

Country Link
US (1) US5488135A (enExample)
EP (1) EP0539326B1 (enExample)
JP (1) JP2543298B2 (enExample)
KR (1) KR930007880A (enExample)
AT (1) ATE136536T1 (enExample)
AU (1) AU653441B2 (enExample)
CA (1) CA2080555C (enExample)
CZ (1) CZ282473B6 (enExample)
DE (1) DE69209771T2 (enExample)
DK (1) DK0539326T3 (enExample)
ES (1) ES2087499T3 (enExample)
FI (1) FI924657L (enExample)
GB (1) GB9121943D0 (enExample)
GR (1) GR3019856T3 (enExample)
HK (1) HK146696A (enExample)
HU (2) HU215151B (enExample)
IL (1) IL103417A (enExample)
MX (1) MX9205921A (enExample)
NO (1) NO178540C (enExample)
NZ (1) NZ244730A (enExample)
PH (1) PH31113A (enExample)
RO (1) RO111074B1 (enExample)
RU (1) RU2118311C1 (enExample)
SG (1) SG50542A1 (enExample)
SK (1) SK312592A3 (enExample)
TW (1) TW221051B (enExample)
ZA (1) ZA928021B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9801828A3 (en) * 1995-03-14 2001-02-28 Novartis Ag Benzoic acid, quinoline and quinazoline derivatives, pharmaceutical compositions containing them and process for producing them
DE10015525A1 (de) * 2000-03-30 2001-10-11 Deutsches Krebsforsch Synthetische Derivate von Lunularsäure, Arzneimittel enthaltend diese Verbindung, Verfahren zur Herstellung der Lunularsäurederivate sowie deren Verwendung
US7103979B2 (en) 2001-04-20 2006-09-12 Hitachi Koki Co., Ltd. Portable electric cutting device with blower mechanism
ES2204300B1 (es) * 2002-07-18 2005-05-01 J. URIACH & CIA S.A. Nuevos derivados del acido 2,4-dihidroxibenzoico.
TWI256334B (en) 2002-10-22 2006-06-11 Hitachi Koki Kk Portable electric cutting device with blower mechanism
JP3765425B2 (ja) 2004-01-26 2006-04-12 日立工機株式会社 携帯用電動切断機

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE293108C (enExample) *
DE269619C (enExample) *
US3657430A (en) * 1969-06-25 1972-04-18 Merck & Co Inc Composition and methods for treating inflammation
DE3066406D1 (en) * 1979-09-13 1984-03-08 Wellcome Found Diaryl compounds and pharmaceutical formulations containing them
JPH01501790A (ja) * 1986-11-19 1989-06-22 ケメックス ファーマシューティカルズ,インコーポレイティド リポキシゲナーゼ阻害剤
WO1988003806A1 (en) * 1986-11-19 1988-06-02 Chemex Pharmaceuticals, Inc. Pharmacologically active compositions of catecholic butanes with zinc
HUT60458A (en) * 1991-02-01 1992-09-28 Sandoz Ag Process for producing benzyloxyphenyl derivatives and pharmaceutical compositions comprising same
CA2102780C (en) * 1991-05-10 2007-01-09 Alfred P. Spada Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase

Also Published As

Publication number Publication date
NO923983L (no) 1993-04-19
SG50542A1 (en) 2000-05-23
CA2080555A1 (en) 1993-04-17
HK146696A (en) 1996-08-09
GB9121943D0 (en) 1991-11-27
DK0539326T3 (da) 1996-05-20
AU653441B2 (en) 1994-09-29
DE69209771D1 (de) 1996-05-15
FI924657A0 (fi) 1992-10-14
EP0539326B1 (en) 1996-04-10
ES2087499T3 (es) 1996-07-16
CZ282473B6 (cs) 1997-07-16
ATE136536T1 (de) 1996-04-15
TW221051B (enExample) 1994-02-11
HUT62850A (en) 1993-06-28
JP2543298B2 (ja) 1996-10-16
RO111074B1 (ro) 1996-06-28
CZ312592A3 (en) 1993-05-12
PH31113A (en) 1998-02-23
JPH05213828A (ja) 1993-08-24
FI924657A7 (fi) 1993-04-17
ZA928021B (en) 1994-04-18
EP0539326A2 (en) 1993-04-28
US5488135A (en) 1996-01-30
NO923983D0 (no) 1992-10-14
RU2118311C1 (ru) 1998-08-27
NO178540C (no) 1996-04-17
FI924657L (fi) 1993-04-17
MX9205921A (es) 1993-04-01
SK312592A3 (en) 1995-03-08
KR930007880A (ko) 1993-05-20
HU215151B (hu) 1998-12-28
AU2704492A (en) 1993-04-22
IL103417A (en) 1997-01-10
EP0539326A3 (en) 1993-07-21
IL103417A0 (en) 1993-03-15
NO178540B (no) 1996-01-08
DE69209771T2 (de) 1996-10-31
HU211233A9 (en) 1995-11-28
NZ244730A (en) 1994-10-26
GR3019856T3 (en) 1996-08-31
HU9203156D0 (en) 1992-12-28

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