CA2014119A1 - Methodes et dispositifs pour la separation du plasma ou du serum du sang entier, collecte de plasma ou de serum et reactifs - Google Patents

Methodes et dispositifs pour la separation du plasma ou du serum du sang entier, collecte de plasma ou de serum et reactifs

Info

Publication number
CA2014119A1
CA2014119A1 CA2014119A CA2014119A CA2014119A1 CA 2014119 A1 CA2014119 A1 CA 2014119A1 CA 2014119 A CA2014119 A CA 2014119A CA 2014119 A CA2014119 A CA 2014119A CA 2014119 A1 CA2014119 A1 CA 2014119A1
Authority
CA
Canada
Prior art keywords
matrix
plasma
serum
sintered
filter means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2014119A
Other languages
English (en)
Other versions
CA2014119C (fr
Inventor
Diane L. Aunet
Kristin D. Elmore
Gradimir G. Georgevich
Tzyy-Wen Jeng
Gary M. Oosta
Terry A. Pry
Neal A. Siegel
Cathy R. Silverman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Diane L. Aunet
Kristin D. Elmore
Gradimir G. Georgevich
Tzyy-Wen Jeng
Gary M. Oosta
Terry A. Pry
Neal A. Siegel
Cathy R. Silverman
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/335,064 external-priority patent/US4933092A/en
Priority claimed from US07/499,864 external-priority patent/US5064541A/en
Application filed by Diane L. Aunet, Kristin D. Elmore, Gradimir G. Georgevich, Tzyy-Wen Jeng, Gary M. Oosta, Terry A. Pry, Neal A. Siegel, Cathy R. Silverman, Abbott Laboratories filed Critical Diane L. Aunet
Publication of CA2014119A1 publication Critical patent/CA2014119A1/fr
Application granted granted Critical
Publication of CA2014119C publication Critical patent/CA2014119C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1607—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous
    • B01D39/1623—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin
    • B01D39/163—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin sintered or bonded
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1638—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being particulate
    • B01D39/1653—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being particulate of synthetic origin
    • B01D39/1661—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being particulate of synthetic origin sintered or bonded
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/18—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being cellulose or derivatives thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/20—Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2003—Glass or glassy material
    • B01D39/2006—Glass or glassy material the material being particulate
    • B01D39/201—Glass or glassy material the material being particulate sintered or bonded by inorganic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/20—Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2027—Metallic material
    • B01D39/2031—Metallic material the material being particulate
    • B01D39/2034—Metallic material the material being particulate sintered or bonded by inorganic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/20—Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2068—Other inorganic materials, e.g. ceramics
    • B01D39/2072—Other inorganic materials, e.g. ceramics the material being particulate or granular
    • B01D39/2075—Other inorganic materials, e.g. ceramics the material being particulate or granular sintered or bonded by inorganic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
CA002014119A 1989-04-07 1990-04-06 Methodes et dispositifs pour la separation du plasma ou du serum du sang entier, collecte de plasma ou de serum et reactifs Expired - Fee Related CA2014119C (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US07/335,064 US4933092A (en) 1989-04-07 1989-04-07 Methods and devices for the separation of plasma or serum from whole blood
US335,064 1989-04-07
US49992890A 1990-03-27 1990-03-27
US499,864 1990-03-27
US07/499,864 US5064541A (en) 1989-04-07 1990-03-27 Devices and methods for the collection of a predetermined volume of plasma or serum
US499,928 1990-03-27

Publications (2)

Publication Number Publication Date
CA2014119A1 true CA2014119A1 (fr) 1990-10-07
CA2014119C CA2014119C (fr) 2000-11-21

Family

ID=27407026

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002014119A Expired - Fee Related CA2014119C (fr) 1989-04-07 1990-04-06 Methodes et dispositifs pour la separation du plasma ou du serum du sang entier, collecte de plasma ou de serum et reactifs

Country Status (8)

Country Link
EP (1) EP0392377B1 (fr)
JP (3) JP2940990B2 (fr)
KR (1) KR910016365A (fr)
AT (1) ATE118615T1 (fr)
AU (1) AU630942B2 (fr)
CA (1) CA2014119C (fr)
DE (1) DE69016813T2 (fr)
ES (1) ES2070942T3 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210215667A1 (en) * 2018-07-11 2021-07-15 Shenzhen Huachuang Bio-pharmaceutical Technology Co., Ltd. Mercury-free p-hydroxyl phenylalanine detection reagent and preparation method and application thereof

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001410B (el) * 1991-08-02 1993-11-30 Ortho Pharma Corp Επινόημα & μέ?οδος διεξαγωγής βιολογικών δοκιμασιών περιέχοντας σύστημα μοριακής διαλογής.
FI940823A0 (fi) * 1994-02-22 1994-02-22 Orion Yhtymae Oy Analysatorkyvett foer turbidimetriska och nefelometriska bestaemningar av helblodsprov
GB9422504D0 (en) 1994-11-08 1995-01-04 Robertson Patricia M B Blood testing
US6540962B1 (en) * 1997-03-03 2003-04-01 Kyoto Daiichi Kagaku Co., Ltd. Testing instrument for analyzing liquid sample
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
JP2000187032A (ja) * 1998-12-21 2000-07-04 Nagase & Co Ltd 血清分離方法及び装置
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
JP3418374B2 (ja) * 2000-11-06 2003-06-23 株式会社いかがく 乾燥型試料搬送容器
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
CA2799371A1 (fr) 2001-02-07 2002-08-29 Massachusetts Institute Of Technology Systeme de detection opto-electronique
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
JP4191051B2 (ja) * 2002-02-27 2008-12-03 三光純薬株式会社 血漿又は血清分離具
JPWO2005012557A1 (ja) * 2003-08-04 2007-11-22 株式会社三和化学研究所 赤血球採取方法及びソルビトール測定方法
WO2005124347A1 (fr) * 2004-06-15 2005-12-29 Ani Biotech Oy Dispositif de filtre, procédé, kit et utilisation de celui-ci
FI20040825A0 (fi) 2004-06-15 2004-06-15 Ani Biotech Oy Suodatinväline, sen käyttö, menetelmä ja kitti
US20080070308A1 (en) * 2004-06-28 2008-03-20 Thomas Ruhland Portous Article For Delivering Chemical Substances
JP4621862B2 (ja) * 2005-02-17 2011-01-26 財団法人ヒューマンサイエンス振興財団 化学センサ
EP2410335A1 (fr) * 2005-11-30 2012-01-25 Massachusetts Institute of Technology (MIT) Biocapteur pour la détection d'agents pathogènes
WO2009068024A1 (fr) * 2007-11-26 2009-06-04 Atonomics A/S Dispositif de séparation comprenant une barrière physique
EP2227269B1 (fr) * 2007-12-12 2021-04-28 Micropoint Bioscience Inc. Filtration rapide et efficace du sang entier dans un dispositif d'écoulement capillaire
MX2011000794A (es) 2008-07-21 2011-02-24 Becton Dickinson Co Dispositivo de separacion de fase por densidad.
EP4119228A1 (fr) 2009-05-15 2023-01-18 Becton, Dickinson and Company Dispositif de séparation de phases de densité
US9198609B2 (en) 2011-04-19 2015-12-01 Porex Corporation Cards for sample storage and delivery comprising sintered porous plastic
EP2721407B1 (fr) * 2011-06-15 2017-09-20 Pfaff, Tim Séparateur de plasma ou de sérum
KR102211991B1 (ko) * 2011-11-11 2021-02-05 엑시스-시일드 에이에스 혈액 샘플 분석 방법
WO2013147308A1 (fr) 2012-03-30 2013-10-03 積水メディカル株式会社 Bande de test immunochromatographique et procédé de détection par immunochromatographie pour détecter une cible dans un échantillon contenant des globules rouges.
WO2013147307A1 (fr) 2012-03-30 2013-10-03 積水メディカル株式会社 Bande de test immunochromatographique et procédé de détection par immunochromatographie pour détecter une cible dans un échantillon contenant des globules rouges.
FR3012972A1 (fr) 2013-11-14 2015-05-15 Biomerieux Sa Nouveau milieu filtrant pour l'obtention de plasma, dispositif et procede de filtration associes
WO2015085066A1 (fr) * 2013-12-06 2015-06-11 BacterioScan Inc. Cuvette de mesure optique comportant des chambres à échantillons
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
CN110780066A (zh) 2014-12-16 2020-02-11 积水医疗株式会社 用于检测含红细胞的样品中的对象物的免疫色谱用测试条、及使用该测试条的免疫色谱
CN115161178A (zh) 2015-09-09 2022-10-11 集联健康有限公司 用于样品收集、稳定化和保存的系统、方法和装置
CN111220431A (zh) * 2016-10-26 2020-06-02 上海万承生物科技有限公司 一种检测血浆活性成分方法及应用该方法的血浆卡
TWI786079B (zh) 2017-01-10 2022-12-11 美商集聯健康有限公司 用於收集及儲存血液的裝置
US10793327B2 (en) 2017-10-09 2020-10-06 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
CN110018301A (zh) * 2018-01-09 2019-07-16 上海八通生物科技股份有限公司 一种组合式免疫层析装置
CN109529958A (zh) * 2018-12-14 2019-03-29 上海艾瑞德生物科技有限公司 全血过滤和血浆定量微流控芯片
US11609042B2 (en) 2019-03-14 2023-03-21 Terumo Bct Biotechnologies, Llc Multi-part lyophilization container and method of use
CN112569686B (zh) * 2019-09-30 2022-08-09 成都易态科技有限公司 复合多孔薄膜的制备方法
WO2021171378A1 (fr) * 2020-02-25 2021-09-02 Ｂｌｕｅ Ｉｎｄｕｓｔｒｉｅｓ株式会社 Dispositif de séparation, dispositif de détection, dispositif de conservation et capteur
JP2023524369A (ja) * 2020-03-18 2023-06-12 ドローブリッジ ヘルス，インコーポレイテッド サンプル採取のためのシステムおよび方法
WO2023154110A1 (fr) * 2022-02-11 2023-08-17 Abbott Point Of Care Inc. Appareil et dispositifs de traitement d'échantillons de fluide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310430A (en) * 1979-09-11 1982-01-12 Terumo Corporation α-Olefin-dialkylmaleate-based liquid separating agent
DE3323973A1 (de) * 1983-07-02 1985-01-03 Boehringer Mannheim Gmbh, 6800 Mannheim Erythrozyten-rueckhaltesubstrate
ATE79679T1 (de) * 1985-10-11 1992-09-15 Abbott Lab Diagnostische probe.
US4753776A (en) * 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
DE3729001A1 (de) * 1987-08-31 1989-03-09 Behringwerke Ag Vorrichtung und verfahren zur abtrennung von blutzellen aus koerperfluessigkeiten, die erythrozyten enthalten, und deren verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210215667A1 (en) * 2018-07-11 2021-07-15 Shenzhen Huachuang Bio-pharmaceutical Technology Co., Ltd. Mercury-free p-hydroxyl phenylalanine detection reagent and preparation method and application thereof

Also Published As

Publication number Publication date
JP2000329761A (ja) 2000-11-30
DE69016813T2 (de) 1995-09-07
JP2940990B2 (ja) 1999-08-25
JPH11230963A (ja) 1999-08-27
EP0392377A3 (en) 1990-11-22
ATE118615T1 (de) 1995-03-15
DE69016813D1 (de) 1995-03-23
CA2014119C (fr) 2000-11-21
AU5306290A (en) 1990-10-11
EP0392377A2 (fr) 1990-10-17
EP0392377B1 (fr) 1995-02-15
AU630942B2 (en) 1992-11-12
ES2070942T3 (es) 1995-06-16
JPH03205563A (ja) 1991-09-09
KR910016365A (ko) 1991-11-05

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