DE69016813D1 - Verfahren und Vorrichtung zur Trennung von Plasma oder von Serum aus Blut. - Google Patents

Verfahren und Vorrichtung zur Trennung von Plasma oder von Serum aus Blut.

Info

Publication number
DE69016813D1
DE69016813D1 DE69016813T DE69016813T DE69016813D1 DE 69016813 D1 DE69016813 D1 DE 69016813D1 DE 69016813 T DE69016813 T DE 69016813T DE 69016813 T DE69016813 T DE 69016813T DE 69016813 D1 DE69016813 D1 DE 69016813D1
Authority
DE
Germany
Prior art keywords
matrix
serum
plasma
sintered
filter means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69016813T
Other languages
English (en)
Other versions
DE69016813T2 (de
Inventor
Diane L Aunet
Kristin D Elmore
Gradimir G Georgevich
Gary M Oosta
Neal A Siegel
Tzyy-Wen Jeng
Terry A Pry
Cathy R Silverman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/335,064 external-priority patent/US4933092A/en
Priority claimed from US07/499,864 external-priority patent/US5064541A/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69016813D1 publication Critical patent/DE69016813D1/de
Publication of DE69016813T2 publication Critical patent/DE69016813T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/14Other self-supporting filtering material ; Other filtering material
    • B01D39/16Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1607Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous
    • B01D39/1623Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin
    • B01D39/163Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin sintered or bonded
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/14Other self-supporting filtering material ; Other filtering material
    • B01D39/16Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/1638Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being particulate
    • B01D39/1653Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being particulate of synthetic origin
    • B01D39/1661Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being particulate of synthetic origin sintered or bonded
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/14Other self-supporting filtering material ; Other filtering material
    • B01D39/16Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
    • B01D39/18Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being cellulose or derivatives thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/14Other self-supporting filtering material ; Other filtering material
    • B01D39/20Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2003Glass or glassy material
    • B01D39/2006Glass or glassy material the material being particulate
    • B01D39/201Glass or glassy material the material being particulate sintered or bonded by inorganic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/14Other self-supporting filtering material ; Other filtering material
    • B01D39/20Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2027Metallic material
    • B01D39/2031Metallic material the material being particulate
    • B01D39/2034Metallic material the material being particulate sintered or bonded by inorganic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/14Other self-supporting filtering material ; Other filtering material
    • B01D39/20Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2068Other inorganic materials, e.g. ceramics
    • B01D39/2072Other inorganic materials, e.g. ceramics the material being particulate or granular
    • B01D39/2075Other inorganic materials, e.g. ceramics the material being particulate or granular sintered or bonded by inorganic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525Multi-layer analytical elements
    • G01N33/526Multi-layer analytical elements the element being adapted for a specific analyte
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Geology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Ceramic Engineering (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69016813T 1989-04-07 1990-04-06 Verfahren und Vorrichtung zur Trennung von Plasma oder von Serum aus Blut. Expired - Fee Related DE69016813T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/335,064 US4933092A (en) 1989-04-07 1989-04-07 Methods and devices for the separation of plasma or serum from whole blood
US49992890A 1990-03-27 1990-03-27
US07/499,864 US5064541A (en) 1989-04-07 1990-03-27 Devices and methods for the collection of a predetermined volume of plasma or serum

Publications (2)

Publication Number Publication Date
DE69016813D1 true DE69016813D1 (de) 1995-03-23
DE69016813T2 DE69016813T2 (de) 1995-09-07

Family

ID=27407026

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69016813T Expired - Fee Related DE69016813T2 (de) 1989-04-07 1990-04-06 Verfahren und Vorrichtung zur Trennung von Plasma oder von Serum aus Blut.

Country Status (8)

Country Link
EP (1) EP0392377B1 (de)
JP (3) JP2940990B2 (de)
KR (1) KR910016365A (de)
AT (1) ATE118615T1 (de)
AU (1) AU630942B2 (de)
CA (1) CA2014119C (de)
DE (1) DE69016813T2 (de)
ES (1) ES2070942T3 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001410B (el) * 1991-08-02 1993-11-30 Ortho Pharma Corp Επινόημα & μέ?οδος διεξαγωγής βιολογικών δοκιμασιών περιέχοντας σύστημα μοριακής διαλογής.
FI940823A0 (fi) * 1994-02-22 1994-02-22 Orion Yhtymae Oy Analysatorkyvett foer turbidimetriska och nefelometriska bestaemningar av helblodsprov
GB9422504D0 (en) 1994-11-08 1995-01-04 Robertson Patricia M B Blood testing
EP0977032B1 (de) * 1997-03-12 2009-07-22 Kyoto Daiichi Kagaku Co., Ltd. Analyseinstrument zum testen von flüssigproben
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
JP2000187032A (ja) * 1998-12-21 2000-07-04 Nagase & Co Ltd 血清分離方法及び装置
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
JP3418374B2 (ja) * 2000-11-06 2003-06-23 株式会社いかがく 乾燥型試料搬送容器
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
JP4295511B2 (ja) 2001-02-07 2009-07-15 マサチューセッツ・インスティテュート・オブ・テクノロジー 光電子による検出システム
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
JP4191051B2 (ja) * 2002-02-27 2008-12-03 三光純薬株式会社 血漿又は血清分離具
JPWO2005012557A1 (ja) * 2003-08-04 2007-11-22 株式会社三和化学研究所 赤血球採取方法及びソルビトール測定方法
WO2005124347A1 (en) * 2004-06-15 2005-12-29 Ani Biotech Oy Filter device, the method, kit and use thereof
FI20040825A0 (fi) 2004-06-15 2004-06-15 Ani Biotech Oy Suodatinväline, sen käyttö, menetelmä ja kitti
US20080070308A1 (en) * 2004-06-28 2008-03-20 Thomas Ruhland Portous Article For Delivering Chemical Substances
JP4621862B2 (ja) * 2005-02-17 2011-01-26 財団法人ヒューマンサイエンス振興財団 化学センサ
EP1974209B1 (de) * 2005-11-30 2013-06-19 Massachusetts Institute of Technology Biosensor zur erkennung von krankheitserregern
WO2009068024A1 (en) * 2007-11-26 2009-06-04 Atonomics A/S Separation device comprising a physical barrier
WO2009075709A1 (en) * 2007-12-12 2009-06-18 Micropoint Bioscience Inc Rapid and efficient filtering whole blood in a capillary flow device
AU2009274096B2 (en) 2008-07-21 2012-08-02 Becton, Dickinson And Company Density phase separation device
RU2552411C2 (ru) 2009-05-15 2015-06-10 Бектон, Дикинсон Энд Компани Устройство разделения фаз с разными плотностями
WO2012145390A1 (en) * 2011-04-19 2012-10-26 Porex Corporation Cards for sample storage and delivery comprising sintered porous plastic
WO2012171560A1 (en) * 2011-06-15 2012-12-20 Pfaff Tim Plasma or serum separator
CN103946711B (zh) * 2011-11-11 2018-12-04 安讯希特技术有限公司 血样本的化验方法
WO2013147308A1 (ja) 2012-03-30 2013-10-03 積水メディカル株式会社 赤血球含有サンプル中の対象物を検出するためのイムノクロマトグラフィー用テストストリップおよびイムノクロマトグラフィーを利用した検出方法
JP5753942B2 (ja) 2012-03-30 2015-07-22 積水メディカル株式会社 赤血球含有サンプル中の対象物を検出するためのイムノクロマトグラフィー用テストストリップおよびイムノクロマトグラフィーを利用した検出方法
FR3012972A1 (fr) 2013-11-14 2015-05-15 Biomerieux Sa Nouveau milieu filtrant pour l'obtention de plasma, dispositif et procede de filtration associes
CN110064446B (zh) 2013-12-06 2022-02-01 Ip专家有限公司 用于对液体样品内粒子的特性进行光学测量的试管组件
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
EP3236261B1 (de) 2014-12-16 2020-09-09 Sekisui Medical Co., Ltd. Teststreifen zur verwendung in der immunchromatografie für den nachweis eines analyten in einer probe mit roten blutkörperchen und immunchromatografie mit diesem teststreifen
ES2963004T3 (es) 2015-09-09 2024-03-22 Drawbridge Health Inc Dispositivos para la recopilación, estabilización y conservación de muestras
CN106526007B (zh) * 2016-10-26 2019-10-25 上海万承生物科技有限公司 一种检测血浆活性成分方法及应用该方法的血浆卡
JP1754772S (ja) 2017-01-10 2023-10-06 サンプル採取器具
EP3694322A1 (de) 2017-10-09 2020-08-19 Terumo BCT Biotechnologies, LLC Lyophilisierungsbehälter und verfahren zu seiner verwendung
CN110018301A (zh) * 2018-01-09 2019-07-16 上海八通生物科技股份有限公司 一种组合式免疫层析装置
CN108872220B (zh) * 2018-07-11 2020-03-24 深圳华创生物医药科技有限公司 一种无汞对羟基苯丙氨酸检测试剂及制备方法和应用
CN109529958A (zh) * 2018-12-14 2019-03-29 上海艾瑞德生物科技有限公司 全血过滤和血浆定量微流控芯片
EP3938742A1 (de) 2019-03-14 2022-01-19 Terumo BCT Biotechnologies, LLC Mehrteiliger lyophilisierungsbehälter und verwendungsverfahren
CN112569686B (zh) * 2019-09-30 2022-08-09 成都易态科技有限公司 复合多孔薄膜的制备方法
WO2021171378A1 (ja) * 2020-02-25 2021-09-02 Blue Industries株式会社 分離装置、検出装置、保存装置及びセンサ
WO2021188594A1 (en) * 2020-03-18 2021-09-23 Drawbridge Health, Inc. Systems and methods for sample collection
WO2023154110A1 (en) * 2022-02-11 2023-08-17 Abbott Point Of Care Inc. Apparatus and devices for processing fluid samples

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310430A (en) * 1979-09-11 1982-01-12 Terumo Corporation α-Olefin-dialkylmaleate-based liquid separating agent
DE3323973A1 (de) * 1983-07-02 1985-01-03 Boehringer Mannheim Gmbh, 6800 Mannheim Erythrozyten-rueckhaltesubstrate
EP0223978B1 (de) * 1985-10-11 1992-08-19 Abbott Laboratories Diagnostische Probe
US4753776A (en) * 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
DE3729001A1 (de) * 1987-08-31 1989-03-09 Behringwerke Ag Vorrichtung und verfahren zur abtrennung von blutzellen aus koerperfluessigkeiten, die erythrozyten enthalten, und deren verwendung

Also Published As

Publication number Publication date
JP2940990B2 (ja) 1999-08-25
DE69016813T2 (de) 1995-09-07
EP0392377A2 (de) 1990-10-17
KR910016365A (ko) 1991-11-05
AU5306290A (en) 1990-10-11
EP0392377A3 (en) 1990-11-22
CA2014119C (en) 2000-11-21
ES2070942T3 (es) 1995-06-16
EP0392377B1 (de) 1995-02-15
CA2014119A1 (en) 1990-10-07
AU630942B2 (en) 1992-11-12
JPH03205563A (ja) 1991-09-09
JP2000329761A (ja) 2000-11-30
JPH11230963A (ja) 1999-08-27
ATE118615T1 (de) 1995-03-15

Similar Documents

Publication Publication Date Title
DE69016813T2 (de) Verfahren und Vorrichtung zur Trennung von Plasma oder von Serum aus Blut.
US5064541A (en) Devices and methods for the collection of a predetermined volume of plasma or serum
US3888629A (en) Performance of chemical or biological reactions within an absorbent matrix pad
US4906439A (en) Biological diagnostic device and method of use
US4933092A (en) Methods and devices for the separation of plasma or serum from whole blood
ES8707799A1 (es) Perfeccionamientos en los aparatos para ajustar el nivel de un liquido, para analisis clinicos y similares
EP0073551A2 (de) Gefäss für Sammlung von Proben
DE3687276D1 (de) Festphaseanalytische vorrichtung und verfahren zu ihrer verwendung.
EP0979403A1 (de) Membranladeeinrichtung für gelelektroforese
CA2075193A1 (en) Specimen test unit
JP2007520693A (ja) 被検体物のマイクロ流体デバイスへの取り込みならびに収納の方法および装置
GB1489913A (en) Method and device for the quantitative determination of a substance having a specific binding affinity for another substance
DE69528645D1 (de) Verfahren und vorrichtung zur sammlung, lagerung und echtzeitanalyse von blut und anderen körperflüssigkeiten
SE8406219L (sv) Sett och anordning for utforande av biokemiska analyser
ATE20977T1 (de) Vorrichtung zur probevorbereitung fuer mehrfachanalyse.
EP0239174B1 (de) Vorrichtung zur biologischen Diagnose
JPS6421362A (en) Method and apparatus for separating and testing whole blood
JPH08278303A (ja) バイオロジカル・マテリアルを単離する方法
ATE51083T1 (de) Vorrichtung und verfahren fuer immunoassay.
EP0797097A1 (de) Partikel-Immunoassay mit kompakter Matrix
AU2017246327B2 (en) Multiple path sample collection card
WO1996027787A1 (en) Membrane loader for gel electrophoresis
ATE53912T1 (de) Verfahren zur konzentrierung und bestimmung von biomolekuelen und zellen.
US5827677A (en) Method and device for specifically detecting myoglobin using a non-discriminating peroxidase sensitive assay

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee