CA1327805C - Pilocarpine derivatives - Google Patents

Pilocarpine derivatives

Info

Publication number
CA1327805C
CA1327805C CA000557576A CA557576A CA1327805C CA 1327805 C CA1327805 C CA 1327805C CA 000557576 A CA000557576 A CA 000557576A CA 557576 A CA557576 A CA 557576A CA 1327805 C CA1327805 C CA 1327805C
Authority
CA
Canada
Prior art keywords
compound
methyl
formula
acid addition
addition salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000557576A
Other languages
English (en)
French (fr)
Inventor
Rene Amstutz
Georg Bolliger
Gideon Shapiro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1327805C publication Critical patent/CA1327805C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA000557576A 1987-01-31 1988-01-28 Pilocarpine derivatives Expired - Fee Related CA1327805C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3702940 1987-01-31
DEP3702940.1 1987-01-31

Publications (1)

Publication Number Publication Date
CA1327805C true CA1327805C (en) 1994-03-15

Family

ID=6319976

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000557576A Expired - Fee Related CA1327805C (en) 1987-01-31 1988-01-28 Pilocarpine derivatives

Country Status (27)

Country Link
US (1) US4835174A (OSRAM)
JP (1) JPS63201185A (OSRAM)
KR (1) KR880009013A (OSRAM)
AT (1) AT395852B (OSRAM)
AU (1) AU607966B2 (OSRAM)
BE (1) BE1001005A3 (OSRAM)
CA (1) CA1327805C (OSRAM)
CH (1) CH675721A5 (OSRAM)
CS (1) CS411291A3 (OSRAM)
DK (1) DK46288A (OSRAM)
ES (1) ES2008421A6 (OSRAM)
FI (1) FI90080C (OSRAM)
FR (1) FR2610322B1 (OSRAM)
GB (1) GB2200910B (OSRAM)
GR (1) GR880100042A (OSRAM)
HU (1) HU204047B (OSRAM)
IE (1) IE61989B1 (OSRAM)
IL (1) IL85252A (OSRAM)
IT (1) IT1219827B (OSRAM)
LU (1) LU87122A1 (OSRAM)
MY (1) MY102415A (OSRAM)
NL (1) NL8800099A (OSRAM)
NZ (1) NZ223359A (OSRAM)
PH (1) PH24837A (OSRAM)
PT (1) PT86666B (OSRAM)
SE (1) SE466150B (OSRAM)
ZA (1) ZA88665B (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882343A (en) * 1987-08-28 1989-11-21 G. D. Searle & Co. Biarylalkylimidazole derivatives as anti-depressants
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
EP3651747A4 (en) 2017-11-17 2020-07-22 Cellix Bio Private Limited COMPOSITIONS AND METHODS OF TREATMENT OF EYE DISORDERS

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2457047A (en) * 1946-02-13 1948-12-21 Monsanto Chemicals 2-(2'-thenyl)-4, 5-dihydroimidazoles and process for making the same
GB1601310A (en) * 1978-05-23 1981-10-28 Lilly Industries Ltd Aryl hydantoins
JPS56131579A (en) * 1980-03-17 1981-10-15 Kissei Pharmaceut Co Ltd Novel 1-substituted imidazole derivative
JPS58150566A (ja) * 1982-03-03 1983-09-07 Yoshitomi Pharmaceut Ind Ltd 新規イミダゾ−ル誘導体
DE3228266A1 (de) * 1982-07-29 1984-02-02 A. Nattermann & Cie GmbH, 5000 Köln Imidazolylalkylthiophene, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3329028A1 (de) * 1983-08-11 1985-02-28 Cassella Ag, 6000 Frankfurt Substituierte (2-amino-2-imidazolin-1-yl)-essigsaeurederivate, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen

Also Published As

Publication number Publication date
GB2200910B (en) 1991-01-16
PT86666B (pt) 1992-04-30
CS411291A3 (en) 1992-06-17
IE880244L (en) 1988-07-31
BE1001005A3 (fr) 1989-06-06
IE61989B1 (en) 1994-12-14
MY102415A (en) 1992-06-17
GR880100042A (el) 1988-12-16
SE466150B (sv) 1992-01-07
HU204047B (en) 1991-11-28
DK46288D0 (da) 1988-01-29
KR880009013A (ko) 1988-09-13
ZA88665B (en) 1989-09-27
FR2610322B1 (fr) 1990-02-16
GB2200910A (en) 1988-08-17
PH24837A (en) 1990-10-30
SE8800293D0 (sv) 1988-01-29
FI880430L (fi) 1988-08-01
HUT50168A (en) 1989-12-28
IT1219827B (it) 1990-05-24
AT395852B (de) 1993-03-25
NL8800099A (nl) 1988-08-16
GB8801804D0 (en) 1988-02-24
CH675721A5 (OSRAM) 1990-10-31
NZ223359A (en) 1991-03-26
IT8847578A0 (it) 1988-01-29
US4835174A (en) 1989-05-30
FI90080C (fi) 1993-12-27
DK46288A (da) 1988-08-01
FI90080B (fi) 1993-09-15
FI880430A0 (fi) 1988-01-29
PT86666A (pt) 1988-02-01
FR2610322A1 (fr) 1988-08-05
LU87122A1 (fr) 1988-08-23
ATA18288A (de) 1992-08-15
IL85252A (en) 1992-03-29
SE8800293L (sv) 1988-08-01
AU1096088A (en) 1988-08-04
ES2008421A6 (es) 1989-07-16
IL85252A0 (en) 1988-07-31
JPS63201185A (ja) 1988-08-19
AU607966B2 (en) 1991-03-21

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Legal Events

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