CA1276032C - Polyene compounds - Google Patents

Polyene compounds

Info

Publication number
CA1276032C
CA1276032C CA000430391A CA430391A CA1276032C CA 1276032 C CA1276032 C CA 1276032C CA 000430391 A CA000430391 A CA 000430391A CA 430391 A CA430391 A CA 430391A CA 1276032 C CA1276032 C CA 1276032C
Authority
CA
Canada
Prior art keywords
alkyl
formula
amino
alkoxy
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000430391A
Other languages
English (en)
French (fr)
Inventor
Ernst P. Krebs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1276032C publication Critical patent/CA1276032C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000430391A 1982-06-24 1983-06-14 Polyene compounds Expired - Fee Related CA1276032C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH3889/82 1982-06-24
CH3889/82A CH651007A5 (de) 1982-06-24 1982-06-24 Polyenverbindungen.

Publications (1)

Publication Number Publication Date
CA1276032C true CA1276032C (en) 1990-11-06

Family

ID=4265678

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000430391A Expired - Fee Related CA1276032C (en) 1982-06-24 1983-06-14 Polyene compounds

Country Status (19)

Country Link
JP (1) JPS5910547A (ja)
AT (1) AT392780B (ja)
AU (1) AU560027B2 (ja)
BE (1) BE897118A (ja)
CA (1) CA1276032C (ja)
CH (1) CH651007A5 (ja)
DE (1) DE3321662A1 (ja)
DK (1) DK159392C (ja)
FR (1) FR2529201B1 (ja)
GB (2) GB2122200B (ja)
IE (1) IE55285B1 (ja)
IL (1) IL69028A0 (ja)
IT (1) IT1212753B (ja)
LU (1) LU84870A1 (ja)
NL (1) NL8302136A (ja)
NZ (1) NZ204628A (ja)
PH (1) PH20070A (ja)
SE (1) SE454984B (ja)
ZA (1) ZA834473B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203634B (it) * 1984-08-13 1989-02-15 Oreal Derivati 1-sostituiti del 4-metossi-2,3,6-trimetilbenzene loro procedimento di preparazione e composizioni medicamentose e cosmetiche che li contengono
FR2621912B1 (fr) * 1987-10-16 1990-03-02 Oreal Nouveaux derives du norbornane, leur procede de preparation et compositions cosmetique et medicamenteuse les contenant
DE4033568A1 (de) * 1990-10-22 1992-04-23 Henkel Kgaa Bicyclische verbindungen mit antiseborrhoischer wirkung
EP0775103B1 (en) * 1994-08-10 1999-06-09 F. Hoffmann-La Roche Ag Retinoic acid x-receptor ligands

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070173B (de) * 1959-12-03 Badische Anilin- S. Soda-Fabrik Aktiengesellschaft, Ludwigshafen / Rhein Verfahren zur Herstellung von 13-[2',6',6'-Trimethylcyclohexen-(l')-yl-(l')]-3,7,ll-trimethyltridecahexaen - (2,4,6,8,10,12) - säureil) bzw. deren Estern
DE923252C (de) * 1944-09-23 1955-02-07 Schering Ag Verfahren zur Herstellung einer Polyencarbonsaeure der Formel CHO
AT207831B (de) * 1957-11-27 1960-02-25 Hoffmann La Roche Verfahren zur Herstellung von Polyencarbonsäureestern und deren Verseifungsprodukten
AT222103B (de) * 1958-08-07 1962-07-10 Bayer Ag Verfahren zur Herstellung von 2-trans-β-Jonylidenessigsäure
CH529742A (de) * 1970-02-02 1972-10-31 Hoffmann La Roche Verfahren zur Herstellung von Vitamin-A-Säureamiden
AT340902B (de) * 1974-03-29 1978-01-10 Hoffmann La Roche Verfahren zur herstellung von neuen polyenverbindungen
DE2456959A1 (de) * 1974-12-03 1976-06-16 Basf Ag 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen
CH624373A5 (en) * 1975-11-14 1981-07-31 Hoffmann La Roche Process for the preparation of polyene compounds
CA1111441A (en) * 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
LU77254A1 (ja) * 1977-05-04 1979-01-18
US4169103A (en) * 1978-04-12 1979-09-25 Hoffmann-La Roche Inc. Nonatetraenoic acid derivatives
DE2843884A1 (de) * 1978-10-07 1980-04-24 Basf Ag Mittel, enthaltend 2-(retinyliden)- malonsaeurederivate

Also Published As

Publication number Publication date
ZA834473B (en) 1984-03-28
FR2529201B1 (fr) 1988-08-19
PH20070A (en) 1986-09-18
CH651007A5 (de) 1985-08-30
NZ204628A (en) 1985-07-31
DE3321662A1 (de) 1983-12-29
SE8303539D0 (sv) 1983-06-20
JPS5910547A (ja) 1984-01-20
NL8302136A (nl) 1984-01-16
AU1620183A (en) 1984-01-05
AT392780B (de) 1991-06-10
GB2156351B (en) 1986-05-14
GB2122200A (en) 1984-01-11
DK159392C (da) 1991-03-04
IL69028A0 (en) 1983-10-31
JPH0441134B2 (ja) 1992-07-07
IE55285B1 (en) 1990-08-01
GB2122200B (en) 1986-05-08
BE897118A (fr) 1983-12-23
IE831471L (en) 1983-12-24
FR2529201A1 (fr) 1983-12-30
AU560027B2 (en) 1987-03-26
SE454984B (sv) 1988-06-13
DE3321662C2 (ja) 1992-11-26
LU84870A1 (de) 1985-03-29
DK287083A (da) 1983-12-25
GB8317129D0 (en) 1983-07-27
IT8321721A0 (it) 1983-06-21
GB8510717D0 (en) 1985-06-05
DK287083D0 (da) 1983-06-21
DK159392B (da) 1990-10-08
IT1212753B (it) 1989-11-30
GB2156351A (en) 1985-10-09
ATA230583A (de) 1990-11-15
SE8303539L (sv) 1983-12-25

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