CA1265785A - Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them - Google Patents

Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them

Info

Publication number
CA1265785A
CA1265785A CA000481808A CA481808A CA1265785A CA 1265785 A CA1265785 A CA 1265785A CA 000481808 A CA000481808 A CA 000481808A CA 481808 A CA481808 A CA 481808A CA 1265785 A CA1265785 A CA 1265785A
Authority
CA
Canada
Prior art keywords
acid
alpha
ester
methoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000481808A
Other languages
English (en)
French (fr)
Inventor
Kumi Yoshida
Goro Kimura
Yoshihiko Hirose
Katsunari Fujita
Fumio Kuzuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amano Enzyme Inc
Original Assignee
Amano Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP11530684A external-priority patent/JPS60258198A/ja
Priority claimed from JP59115307A external-priority patent/JPS60258119A/ja
Priority claimed from JP60085254A external-priority patent/JPS61243099A/ja
Priority claimed from JP60085255A external-priority patent/JPS61243022A/ja
Application filed by Amano Pharmaceutical Co Ltd filed Critical Amano Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1265785A publication Critical patent/CA1265785A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CA000481808A 1984-06-04 1985-05-17 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them Expired - Lifetime CA1265785A (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP115307/1984 1984-06-04
JP115306/1984 1984-06-04
JP11530684A JPS60258198A (ja) 1984-06-04 1984-06-04 トリテルペンアルコ−ル有機酸エステル及びその製造法
JP59115307A JPS60258119A (ja) 1984-06-04 1984-06-04 高脂血症治療剤
JP60085254A JPS61243099A (ja) 1985-04-19 1985-04-19 トリテルペンアルコール有機酸エステル
JP85255/1985 1985-04-19
JP60085255A JPS61243022A (ja) 1985-04-19 1985-04-19 高脂血症治療剤
JP85254/1985 1985-04-19

Publications (1)

Publication Number Publication Date
CA1265785A true CA1265785A (en) 1990-02-13

Family

ID=27467077

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000481808A Expired - Lifetime CA1265785A (en) 1984-06-04 1985-05-17 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them

Country Status (9)

Country Link
US (1) US4748161A (enExample)
EP (1) EP0166542B1 (enExample)
KR (1) KR920007235B1 (enExample)
CA (1) CA1265785A (enExample)
DE (1) DE3579064D1 (enExample)
DK (1) DK246985A (enExample)
ES (1) ES8708125A1 (enExample)
FI (1) FI852216A7 (enExample)
NO (1) NO852246L (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014036655A1 (en) * 2012-09-06 2014-03-13 Mcpharma Biotech Inc. Treatment of diarrhea and post-weaning diarrhea with resistant potato starch

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA876640B (en) * 1986-09-26 1988-03-08 Warner-Lambert Company Treated lipid regulator
US5178864A (en) * 1990-08-14 1993-01-12 Mit Lipoprotein removal by soluble enzymes
JPH09511902A (ja) * 1993-12-29 1997-12-02 藤沢薬品工業株式会社 Ｗｆ１５６０４物質
WO1998001126A2 (en) * 1996-07-05 1998-01-15 Unilever N.V. Method of manufacturing a sterol ester mixture
AU8977698A (en) * 1997-07-25 1999-02-16 Elan Corporation, Plc A process for the preparation of a granulate suitable to the preparation of rapidly disintegrable mouth-soluble tablets
SG93823A1 (en) * 1998-02-13 2003-01-21 Givaudan Roure Int Aryl-acrylic acid esters
FR2811984B1 (fr) * 2000-07-19 2004-02-06 Pharmascience Lab Procede de preparation d'un ester de corps gras et son utilisation dans les domaines pharmaceutique, cosmetique ou alimentaire
US20040054004A1 (en) * 2001-01-12 2004-03-18 Weidner Morten Sloth Dihydro-triterpenes in the treatment of viral infections, cardiovascular disease, in flammation, hypersensitivity or pain
JP2004520343A (ja) * 2001-01-12 2004-07-08 ベエスペ・ファルマ・アクティーゼルスカブ ウイルス感染、心血管疾患、炎症、過敏症、または痛みの処置におけるジヒドロトリテルペン
US8968768B2 (en) * 2004-03-29 2015-03-03 Wyeth Llc Phytosterol nutritional supplements
JP2007332070A (ja) * 2006-06-14 2007-12-27 Tokyo Univ Of Marine Science & Technology ＮＦ−κＢ活性化阻害剤
JP4590491B2 (ja) * 2008-11-19 2010-12-01 森永乳業株式会社 過酸化脂質生成抑制のための医薬
JP5717960B2 (ja) * 2009-12-07 2015-05-13 花王株式会社 油脂組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB932662A (en) * 1960-04-13 1963-07-31 Laroche Navarron Lab Therapeutic compositions comprising butyrospermol
FR89M (enExample) * 1960-07-29 1961-01-09
US3625194A (en) * 1969-05-12 1971-12-07 Serdex Soc D Etudes De Rech De Triterpenic alcohols, process for their preparation and therapeutical compositions containing same
US3686235A (en) * 1969-10-14 1972-08-22 Harold J Nicholas Class of liquid crystals
US4393044A (en) * 1980-05-29 1983-07-12 The Nisshin Oil Mills Limited Steroid ester, and cosmetics and ointments containing the same
JPS57149248A (en) * 1981-03-11 1982-09-14 Tomotaro Tsuchiya Cycloartenol ferulic ester, one component of oryzanol, having action closely related to propagation of animal, pharmaceutical and physiological action of oryzanol
JPS5811959A (ja) * 1981-07-15 1983-01-22 Fuji Xerox Co Ltd 電子複写機の出力チエツク装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014036655A1 (en) * 2012-09-06 2014-03-13 Mcpharma Biotech Inc. Treatment of diarrhea and post-weaning diarrhea with resistant potato starch

Also Published As

Publication number Publication date
EP0166542B1 (en) 1990-08-08
US4748161A (en) 1988-05-31
US4748161B1 (enExample) 1991-10-15
EP0166542A3 (en) 1986-07-09
DE3579064D1 (de) 1990-09-13
DK246985A (da) 1985-12-05
FI852216L (fi) 1985-12-05
FI852216A0 (fi) 1985-06-03
FI852216A7 (fi) 1985-12-05
KR920007235B1 (ko) 1992-08-28
DK246985D0 (da) 1985-06-03
KR860000236A (ko) 1986-01-27
EP0166542A2 (en) 1986-01-02
ES8708125A1 (es) 1987-07-01
NO852246L (no) 1985-12-05
ES544466A0 (es) 1987-07-01

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