JPS57149248A - Cycloartenol ferulic ester, one component of oryzanol, having action closely related to propagation of animal, pharmaceutical and physiological action of oryzanol - Google Patents
Cycloartenol ferulic ester, one component of oryzanol, having action closely related to propagation of animal, pharmaceutical and physiological action of oryzanolInfo
- Publication number
- JPS57149248A JPS57149248A JP3493781A JP3493781A JPS57149248A JP S57149248 A JPS57149248 A JP S57149248A JP 3493781 A JP3493781 A JP 3493781A JP 3493781 A JP3493781 A JP 3493781A JP S57149248 A JPS57149248 A JP S57149248A
- Authority
- JP
- Japan
- Prior art keywords
- oryzanol
- action
- methanol
- give
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Cycloartenol ferulic ester.
USE: A drug having pharmaceutical and physioligical action of oryzanol, useful as a promotor for growth and an estrous agent for animal, a remedy for menopausal disorder or hepatic disorder, a cholesterin deposit inhibitor for the artery, having gonard stimulating effect. Further an antioxidant.
PROCESS: Residuary substances of rice-bran oil and soda oil are dissolved in a water-containing alcohol, acidified weakly with acetic acid, and extracted with an ether. The extracted solution is washed with 5wt% aqueous solution of potassium hydroxide, 3wt% aqueous solution of potassium carbonate, and 3wt% methanol-water solution of potassium hydroxide respectively, and decomposed with acetic acid to give a phenolic substance. This substance is then absorbed on alumina, and an elution fraction of ether and methanol (20:1) is collected, to give a raw ferulic ester, which is purified with 3wt% methanol-water solution of potassium hydroxide, to give the ferulic ester.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3493781A JPS57149248A (en) | 1981-03-11 | 1981-03-11 | Cycloartenol ferulic ester, one component of oryzanol, having action closely related to propagation of animal, pharmaceutical and physiological action of oryzanol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3493781A JPS57149248A (en) | 1981-03-11 | 1981-03-11 | Cycloartenol ferulic ester, one component of oryzanol, having action closely related to propagation of animal, pharmaceutical and physiological action of oryzanol |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57149248A true JPS57149248A (en) | 1982-09-14 |
Family
ID=12428095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3493781A Pending JPS57149248A (en) | 1981-03-11 | 1981-03-11 | Cycloartenol ferulic ester, one component of oryzanol, having action closely related to propagation of animal, pharmaceutical and physiological action of oryzanol |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57149248A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985005623A1 (en) * | 1984-05-25 | 1985-12-19 | Zeria Shinyaku Kogyo Kabushiki Kaisha | Agent for treating arteriosclerosis |
EP0166542A2 (en) * | 1984-06-04 | 1986-01-02 | Amano Pharmaceutical Co., Ltd. | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them |
WO1986000312A1 (en) * | 1984-06-30 | 1986-01-16 | Zeria Shinyaku Kogyo Kabushiki Kaisha | Cycloartenyl ferrulate-cyclodextrin complex |
AU598724B2 (en) * | 1984-06-04 | 1990-07-05 | Amano Pharmaceutical Co., Ltd. | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5531010A (en) * | 1978-08-25 | 1980-03-05 | Okayasu Shoten:Kk | Alkali metal salt of cycloartenol succinic acid ester |
-
1981
- 1981-03-11 JP JP3493781A patent/JPS57149248A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5531010A (en) * | 1978-08-25 | 1980-03-05 | Okayasu Shoten:Kk | Alkali metal salt of cycloartenol succinic acid ester |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985005623A1 (en) * | 1984-05-25 | 1985-12-19 | Zeria Shinyaku Kogyo Kabushiki Kaisha | Agent for treating arteriosclerosis |
EP0166542A2 (en) * | 1984-06-04 | 1986-01-02 | Amano Pharmaceutical Co., Ltd. | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them |
US4748161A (en) * | 1984-06-04 | 1988-05-31 | Amano Pharmaceutical Co., Ltd. | Triterpenyl esters of organic acids and hypolipidemic agents composed of them |
AU598724B2 (en) * | 1984-06-04 | 1990-07-05 | Amano Pharmaceutical Co., Ltd. | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them |
WO1986000312A1 (en) * | 1984-06-30 | 1986-01-16 | Zeria Shinyaku Kogyo Kabushiki Kaisha | Cycloartenyl ferrulate-cyclodextrin complex |
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