CA1254207A - THERAPEUTICALLY USEFUL IMIDAZO¬1,2-.alpha.|PYRIDINE DERIVATIVES - Google Patents

THERAPEUTICALLY USEFUL IMIDAZO¬1,2-.alpha.|PYRIDINE DERIVATIVES

Info

Publication number
CA1254207A
CA1254207A CA000426243A CA426243A CA1254207A CA 1254207 A CA1254207 A CA 1254207A CA 000426243 A CA000426243 A CA 000426243A CA 426243 A CA426243 A CA 426243A CA 1254207 A CA1254207 A CA 1254207A
Authority
CA
Canada
Prior art keywords
radical
imidazo
general formula
pharmaceutically
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000426243A
Other languages
English (en)
French (fr)
Inventor
Pascal George
Jean-Pierre Kaplan
Jean-Michel Bernardon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of CA1254207A publication Critical patent/CA1254207A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA000426243A 1982-04-21 1983-04-20 THERAPEUTICALLY USEFUL IMIDAZO¬1,2-.alpha.|PYRIDINE DERIVATIVES Expired CA1254207A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8206841 1982-04-21
FR8206841A FR2525602A1 (fr) 1982-04-21 1982-04-21 Imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
CA1254207A true CA1254207A (en) 1989-05-16

Family

ID=9273216

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000426243A Expired CA1254207A (en) 1982-04-21 1983-04-20 THERAPEUTICALLY USEFUL IMIDAZO¬1,2-.alpha.|PYRIDINE DERIVATIVES

Country Status (19)

Country Link
US (1) US4492695A (enExample)
EP (1) EP0092459B1 (enExample)
JP (1) JPS58189180A (enExample)
AT (1) ATE23860T1 (enExample)
AU (1) AU553112B2 (enExample)
CA (1) CA1254207A (enExample)
DE (1) DE3367918D1 (enExample)
DK (1) DK173783A (enExample)
ES (1) ES8402298A1 (enExample)
FI (1) FI73998C (enExample)
FR (1) FR2525602A1 (enExample)
GR (1) GR78577B (enExample)
HU (1) HU189648B (enExample)
IE (1) IE54923B1 (enExample)
IL (1) IL68443A0 (enExample)
NO (1) NO156048C (enExample)
NZ (1) NZ203955A (enExample)
PT (1) PT76574B (enExample)
ZA (1) ZA832787B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3406329A1 (de) * 1984-02-22 1985-08-22 Merck Patent Gmbh, 6100 Darmstadt Pyridone
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
US5364849A (en) * 1989-04-22 1994-11-15 John Wyeth & Brother, Limited 1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives
JP2944048B2 (ja) * 1993-07-06 1999-08-30 フアイザー・インコーポレイテツド 二環式テトラヒドロピラゾロピリジン
WO1998025926A1 (en) * 1996-12-11 1998-06-18 Takeda Chemical Industries, Ltd. Imidazopyridine derivatives and their production
AUPP278498A0 (en) 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
WO2001009131A1 (en) * 1999-07-30 2001-02-08 Zenyaku Kogyo Kabushiki Kaisha Azaindolizinone derivatives and cerebral function improvers containing the same as the active ingredient
IT1318624B1 (it) * 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
US8555875B2 (en) 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
US8927545B2 (en) * 2009-03-30 2015-01-06 Duke University Inhibiting Eph B-3 kinase
CN106866667B (zh) 2009-11-05 2019-11-15 圣母大学 咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR20180053386A (ko) 2015-09-17 2018-05-21 마빈 제이. 밀러 마이코박테리아 감염에 대해 유용한 벤질 아민-함유 헤테로사이클릭 화합물 및 조성물
EP3468545A4 (en) 2016-06-08 2020-07-22 President and Fellows of Harvard College METHODS AND COMPOSITIONS FOR REDUCING TACTILE DYSFUNCTION AND ANXIETY ASSOCIATED WITH AUTISM SPECTRUM DISORDER, RETT SYNDROME AND FRAGILE X SYNDROME
CN107163039A (zh) * 2017-05-11 2017-09-15 浙江工业大学 一种6‑甲基‑2‑对甲苯基咪唑并[1,2‑a]吡啶‑3‑甲醛的制备方法
EP3797097A4 (en) 2018-05-22 2022-03-09 President and Fellows of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
US11434244B2 (en) 2018-05-29 2022-09-06 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
EP3946390A4 (en) 2019-03-25 2022-12-21 President and Fellows of Harvard College COMPOSITIONS AND METHODS TO REDUCE TACTILE DYSFUNCTION, ANXIETY AND SOCIAL DISABILITIES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1076089A (en) * 1965-11-09 1967-07-19 Selvi & C Lab Bioterapico New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
JPH0412270B2 (enExample) 1992-03-04
DK173783A (da) 1983-10-22
PT76574A (fr) 1983-05-01
EP0092459A2 (fr) 1983-10-26
ATE23860T1 (de) 1986-12-15
ES521651A0 (es) 1984-01-16
IL68443A0 (en) 1983-07-31
FI831349A0 (fi) 1983-04-20
EP0092459A3 (en) 1984-02-01
AU553112B2 (en) 1986-07-03
FR2525602B1 (enExample) 1984-06-22
NO831390L (no) 1983-10-24
NZ203955A (en) 1985-11-08
ES8402298A1 (es) 1984-01-16
FR2525602A1 (fr) 1983-10-28
US4492695A (en) 1985-01-08
NO156048B (no) 1987-04-06
JPS58189180A (ja) 1983-11-04
HU189648B (en) 1986-07-28
DE3367918D1 (en) 1987-01-15
GR78577B (enExample) 1984-09-27
FI831349L (fi) 1983-10-22
NO156048C (no) 1987-07-15
AU1370083A (en) 1983-10-27
FI73998B (fi) 1987-08-31
PT76574B (fr) 1986-02-27
EP0092459B1 (fr) 1986-11-26
IE830896L (en) 1983-10-21
ZA832787B (en) 1983-12-28
FI73998C (fi) 1987-12-10
IE54923B1 (en) 1990-03-28
DK173783D0 (da) 1983-04-20

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Legal Events

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MKEX Expiry