CA1245232A - Diarylindane - 1,3 - diones, their preparation and use - Google Patents
Diarylindane - 1,3 - diones, their preparation and useInfo
- Publication number
- CA1245232A CA1245232A CA000465254A CA465254A CA1245232A CA 1245232 A CA1245232 A CA 1245232A CA 000465254 A CA000465254 A CA 000465254A CA 465254 A CA465254 A CA 465254A CA 1245232 A CA1245232 A CA 1245232A
- Authority
- CA
- Canada
- Prior art keywords
- phenyl
- compound
- formula
- chlorophenyl
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
- C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/39—Unsaturated compounds containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pens And Brushes (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838327598A GB8327598D0 (en) | 1983-10-14 | 1983-10-14 | Pharmacologically active diarylindane-13-diones |
GB83.27598 | 1983-10-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1245232A true CA1245232A (en) | 1988-11-22 |
Family
ID=10550228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000465254A Expired CA1245232A (en) | 1983-10-14 | 1984-10-12 | Diarylindane - 1,3 - diones, their preparation and use |
Country Status (16)
Country | Link |
---|---|
US (1) | US4569945A (ja) |
EP (1) | EP0138272B1 (ja) |
JP (1) | JPS60109541A (ja) |
KR (1) | KR920003101B1 (ja) |
AT (1) | ATE32214T1 (ja) |
AU (1) | AU561309B2 (ja) |
CA (1) | CA1245232A (ja) |
DE (1) | DE3469020D1 (ja) |
DK (1) | DK491984A (ja) |
ES (1) | ES536743A0 (ja) |
FI (1) | FI82923C (ja) |
GB (1) | GB8327598D0 (ja) |
GR (1) | GR80629B (ja) |
HU (1) | HUT35627A (ja) |
PT (1) | PT79356B (ja) |
ZA (1) | ZA847967B (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2556966B1 (fr) * | 1983-12-26 | 1987-09-25 | Bouchard Sa Laboratoires | Nouvelle application therapeutique d'un derive de l'indane dione et les compositions pharmaceutiques destinees a cet usage |
FR2593501B1 (fr) * | 1986-01-29 | 1988-05-06 | Panmedica Sa | Nouveaux derives bis (r-oxyimino)-5,7 dihydro-6,7 (5h) dibenzo (a,c) cycloheptene, leurs procedes de preparation et leur application comme medicaments |
JP2582898B2 (ja) * | 1989-05-16 | 1997-02-19 | 三菱化学株式会社 | インダン―1,3―ジオン誘導体およびこれを有効成分とする除草剤 |
CN103748060B (zh) * | 2011-06-16 | 2016-04-13 | 韩国化学研究院 | 1,3-二氧代茚衍生物、其药学上可接受的盐或光学异构体,其制备方法以及包含其作为抗病毒活性成分的药物组合物 |
US9790197B2 (en) | 2012-12-14 | 2017-10-17 | Katholieke Universiteit Leuven K.U. Leuven R & D | Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2361517A (en) * | 1939-09-22 | 1944-10-31 | Gen Electric | Sealing apparatus |
DE947473C (de) * | 1953-04-30 | 1956-08-16 | Geigy Ag J R | Verfahren zur Herstellung von 2-(p-Chlorphenyl)-indan-1, 3-dion |
DE1130439B (de) * | 1960-06-27 | 1962-05-30 | Us Vitamin Pharm Corp | Verfahren zur Herstellung von 2-Arylindandionen |
NL128364C (ja) * | 1964-08-27 | |||
GB1172696A (en) * | 1966-10-20 | 1969-12-03 | Koninklijke Pharma Fab Nv | Phenyl-Indandione Derivatives |
US3784606A (en) * | 1968-08-29 | 1974-01-08 | Pfizer | Novel 2-aryl-1,3-indandiones and 2-aryl-2,3-dihydrobenz(f)indene-1,3-diones |
US3879468A (en) * | 1969-04-14 | 1975-04-22 | Union Carbide Corp | 2-(poly substituted phenyl)-1,3-indandione compounds |
US3803240A (en) * | 1969-04-14 | 1974-04-09 | Union Carbide Corp | 2-(2,6-substituted-phenyl)-1,3-indandiones |
US3784605A (en) * | 1971-05-13 | 1974-01-08 | Union Carbide Corp | 2-(polysubstituted phenyl)-1,3-indandione compounds |
GB1380089A (en) * | 1972-01-20 | 1975-01-08 | Istituto Gentilipisa Spa | 2-aryl-1,3-indandiones |
US3978231A (en) * | 1972-01-25 | 1976-08-31 | Beecham Group Limited | Pharmaceutical compositions and method of treating allergic conditions utilizing 2-nitroindane-1,3-dione derivatives as the active agents |
US3976681A (en) * | 1973-10-12 | 1976-08-24 | Merck & Co., Inc. | [1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids |
FR2392951A2 (fr) * | 1975-02-07 | 1978-12-29 | Creat Lab | Nouveaux derives de la ninhydrine, leurs procedes de preparation et medicaments contenant ces derives |
-
1983
- 1983-10-14 GB GB838327598A patent/GB8327598D0/en active Pending
-
1984
- 1984-10-10 EP EP84201452A patent/EP0138272B1/en not_active Expired
- 1984-10-10 AT AT84201452T patent/ATE32214T1/de not_active IP Right Cessation
- 1984-10-10 DE DE8484201452T patent/DE3469020D1/de not_active Expired
- 1984-10-11 ES ES536743A patent/ES536743A0/es active Granted
- 1984-10-11 ZA ZA847967A patent/ZA847967B/xx unknown
- 1984-10-12 DK DK491984A patent/DK491984A/da not_active Application Discontinuation
- 1984-10-12 JP JP59214083A patent/JPS60109541A/ja active Pending
- 1984-10-12 PT PT79356A patent/PT79356B/pt not_active IP Right Cessation
- 1984-10-12 FI FI844020A patent/FI82923C/fi not_active IP Right Cessation
- 1984-10-12 AU AU34184/84A patent/AU561309B2/en not_active Ceased
- 1984-10-12 GR GR80629A patent/GR80629B/el unknown
- 1984-10-12 HU HU843840A patent/HUT35627A/hu unknown
- 1984-10-12 CA CA000465254A patent/CA1245232A/en not_active Expired
- 1984-10-12 US US06/660,287 patent/US4569945A/en not_active Expired - Fee Related
- 1984-10-13 KR KR1019840006356A patent/KR920003101B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK491984D0 (da) | 1984-10-12 |
KR920003101B1 (ko) | 1992-04-18 |
EP0138272A1 (en) | 1985-04-24 |
GR80629B (en) | 1985-02-12 |
ES8602582A1 (es) | 1985-11-16 |
KR850003382A (ko) | 1985-06-17 |
DE3469020D1 (en) | 1988-03-03 |
GB8327598D0 (en) | 1983-11-16 |
AU3418484A (en) | 1985-04-18 |
ZA847967B (en) | 1985-05-29 |
FI844020L (fi) | 1985-04-15 |
ES536743A0 (es) | 1985-11-16 |
PT79356B (en) | 1986-09-08 |
FI82923B (fi) | 1991-01-31 |
DK491984A (da) | 1985-04-15 |
EP0138272B1 (en) | 1988-01-27 |
ATE32214T1 (de) | 1988-02-15 |
FI844020A0 (fi) | 1984-10-12 |
JPS60109541A (ja) | 1985-06-15 |
HUT35627A (en) | 1985-07-29 |
US4569945A (en) | 1986-02-11 |
FI82923C (fi) | 1991-05-10 |
AU561309B2 (en) | 1987-05-07 |
PT79356A (en) | 1984-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |