CA1225592A - Refined detoxified endotoxin - Google Patents

Refined detoxified endotoxin

Info

Publication number
CA1225592A
CA1225592A CA000460820A CA460820A CA1225592A CA 1225592 A CA1225592 A CA 1225592A CA 000460820 A CA000460820 A CA 000460820A CA 460820 A CA460820 A CA 460820A CA 1225592 A CA1225592 A CA 1225592A
Authority
CA
Canada
Prior art keywords
rde
endotoxin
composition according
spp
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000460820A
Other languages
English (en)
French (fr)
Inventor
Edgar E. Ribi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ribi Immunochem Research Inc
Original Assignee
Ribi Immunochem Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribi Immunochem Research Inc filed Critical Ribi Immunochem Research Inc
Application granted granted Critical
Publication of CA1225592A publication Critical patent/CA1225592A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA000460820A 1983-08-26 1984-08-10 Refined detoxified endotoxin Expired CA1225592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52696783A 1983-08-26 1983-08-26
US526,967 1983-08-26

Publications (1)

Publication Number Publication Date
CA1225592A true CA1225592A (en) 1987-08-18

Family

ID=24099553

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000460820A Expired CA1225592A (en) 1983-08-26 1984-08-10 Refined detoxified endotoxin

Country Status (22)

Country Link
JP (1) JPS6072825A (nl)
KR (1) KR880002223B1 (nl)
AT (1) AT389228B (nl)
AU (1) AU554039B2 (nl)
BE (1) BE900377A (nl)
CA (1) CA1225592A (nl)
CH (1) CH660125A5 (nl)
DE (2) DE3448164C2 (nl)
DK (1) DK389384A (nl)
ES (1) ES8606883A1 (nl)
FI (1) FI843204A (nl)
FR (1) FR2550945B1 (nl)
GB (1) GB2147806B (nl)
HU (1) HU191713B (nl)
IL (1) IL72675A (nl)
IN (1) IN157910B (nl)
IT (1) IT1177974B (nl)
NL (1) NL192326C (nl)
NO (1) NO843243L (nl)
NZ (1) NZ209233A (nl)
SE (1) SE8404090L (nl)
ZA (1) ZA846309B (nl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629722A (en) * 1984-07-12 1986-12-16 Ribi Immunochem Research, Inc. Method of inhibiting the onset of acute radiation syndrome
US4803070A (en) * 1986-04-15 1989-02-07 Ribi Immunochem Research Inc. Immunological emulsion adjuvants for polysaccharide vaccines
US4806352A (en) * 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
DE10115310A1 (de) * 2001-03-28 2002-10-10 Nodar A Daniela Bakteriophagen-Präparation
KR100868443B1 (ko) * 2002-05-27 2008-11-11 주식회사 포스코 폭과 길이가 가변 조정되는 런치박스 제작장치

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160326B1 (nl) * 1971-11-19 1975-02-07 Anvar
BE793260A (fr) * 1971-12-24 1973-06-22 Pasteur Institut Agent immunostimulant, medicaments le contenant et procede de fabrication de cet agent immunostimulant
DE2527636A1 (de) * 1974-06-20 1976-01-08 Anvar Verfahren zur herstellung von mycobakteriellen fraktionen
FR2393065A1 (fr) * 1977-05-31 1978-12-29 Merieux Inst Procede de separation de lipides d'endotoxines bacteriennes et notamment d'endotoxine de bordetella pertussis
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436728A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4435386A (en) * 1982-05-26 1984-03-06 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product

Also Published As

Publication number Publication date
DE3431058C2 (nl) 1987-06-11
DK389384D0 (da) 1984-08-13
AT389228B (de) 1989-11-10
IL72675A (en) 1988-04-29
IT8448757A1 (it) 1986-02-24
GB2147806A (en) 1985-05-22
HUT34887A (en) 1985-05-28
CH660125A5 (de) 1987-03-31
SE8404090D0 (sv) 1984-08-14
GB2147806B (en) 1986-10-22
HU191713B (en) 1987-03-30
BE900377A (fr) 1985-02-18
DE3448164C2 (nl) 1987-06-25
GB8420612D0 (en) 1984-09-19
KR880002223B1 (ko) 1988-10-20
FR2550945B1 (fr) 1988-09-16
DE3431058A1 (de) 1985-03-07
KR850001696A (ko) 1985-04-01
ATA273384A (de) 1989-04-15
IT8448757A0 (it) 1984-08-24
JPH0556326B2 (nl) 1993-08-19
ZA846309B (en) 1985-03-27
IT1177974B (it) 1987-09-03
ES535124A0 (es) 1986-05-01
SE8404090L (sv) 1985-02-27
FI843204A0 (fi) 1984-08-14
JPS6072825A (ja) 1985-04-24
IN157910B (nl) 1986-07-19
NL192326C (nl) 1997-06-04
DK389384A (da) 1985-02-27
FI843204A (fi) 1985-02-27
NL8402515A (nl) 1985-03-18
AU554039B2 (en) 1986-08-07
IL72675A0 (en) 1984-11-30
NZ209233A (en) 1987-11-27
NL192326B (nl) 1997-02-03
FR2550945A1 (fr) 1985-03-01
NO843243L (no) 1985-02-27
AU3221584A (en) 1985-02-28
ES8606883A1 (es) 1986-05-01

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Legal Events

Date Code Title Description
MKEX Expiry