GB8420612D0 - Refined detoxified endotoxin - Google Patents

Refined detoxified endotoxin

Info

Publication number
GB8420612D0
GB8420612D0 GB848420612A GB8420612A GB8420612D0 GB 8420612 D0 GB8420612 D0 GB 8420612D0 GB 848420612 A GB848420612 A GB 848420612A GB 8420612 A GB8420612 A GB 8420612A GB 8420612 D0 GB8420612 D0 GB 8420612D0
Authority
GB
United Kingdom
Prior art keywords
detoxified endotoxin
refined detoxified
refined
response
endotoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB848420612A
Other versions
GB2147806B (en
GB2147806A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ribi Immunochem Research Inc
Original Assignee
Ribi Immunochem Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribi Immunochem Research Inc filed Critical Ribi Immunochem Research Inc
Publication of GB8420612D0 publication Critical patent/GB8420612D0/en
Publication of GB2147806A publication Critical patent/GB2147806A/en
Application granted granted Critical
Publication of GB2147806B publication Critical patent/GB2147806B/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A composition which is capable of producing an effective adjuvant response or stimulating the immune response of a warm blooded animal which comprises an effective amount of a refined detoxified endotoxin material, in combination with a pharmaceutically acceptable carrier.
GB08420612A 1983-08-26 1984-08-14 Refined detoxified endotoxin compositions Expired GB2147806B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52696783A 1983-08-26 1983-08-26

Publications (3)

Publication Number Publication Date
GB8420612D0 true GB8420612D0 (en) 1984-09-19
GB2147806A GB2147806A (en) 1985-05-22
GB2147806B GB2147806B (en) 1986-10-22

Family

ID=24099553

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08420612A Expired GB2147806B (en) 1983-08-26 1984-08-14 Refined detoxified endotoxin compositions

Country Status (22)

Country Link
JP (1) JPS6072825A (en)
KR (1) KR880002223B1 (en)
AT (1) AT389228B (en)
AU (1) AU554039B2 (en)
BE (1) BE900377A (en)
CA (1) CA1225592A (en)
CH (1) CH660125A5 (en)
DE (2) DE3448164C2 (en)
DK (1) DK389384A (en)
ES (1) ES8606883A1 (en)
FI (1) FI843204A (en)
FR (1) FR2550945B1 (en)
GB (1) GB2147806B (en)
HU (1) HU191713B (en)
IL (1) IL72675A (en)
IN (1) IN157910B (en)
IT (1) IT1177974B (en)
NL (1) NL192326C (en)
NO (1) NO843243L (en)
NZ (1) NZ209233A (en)
SE (1) SE8404090L (en)
ZA (1) ZA846309B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629722A (en) * 1984-07-12 1986-12-16 Ribi Immunochem Research, Inc. Method of inhibiting the onset of acute radiation syndrome
US4803070A (en) * 1986-04-15 1989-02-07 Ribi Immunochem Research Inc. Immunological emulsion adjuvants for polysaccharide vaccines
US4806352A (en) * 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
DE10115310A1 (en) * 2001-03-28 2002-10-10 Nodar A Daniela Bacteriophage preparation
KR100868443B1 (en) * 2002-05-27 2008-11-11 주식회사 포스코 An apparatus for bending a strip packing sheet

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160326B1 (en) * 1971-11-19 1975-02-07 Anvar
BE793260A (en) * 1971-12-24 1973-06-22 Pasteur Institut IMMUNOSTIMULANT AGENT, MEDICINES CONTAINING IT AND METHOD FOR MANUFACTURING SUCH IMMUNOSTIMULANT AGENT
BE830486A (en) * 1974-06-20 1975-12-22 MYCOBACTERIAL FRACTIONS FOR USE AS AN ANTI-INFECTIOUS AGENT, AND PROCESS FOR PREPARATION
FR2393065A1 (en) * 1977-05-31 1978-12-29 Merieux Inst PROCESS FOR SEPARATION OF LIPIDS FROM BACTERIAL ENDOTOXINS AND IN PARTICULAR FROM BORDETELLA PERTUSSIS ENDOTOXIN
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436728A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4435386A (en) * 1982-05-26 1984-03-06 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product

Also Published As

Publication number Publication date
HUT34887A (en) 1985-05-28
IL72675A0 (en) 1984-11-30
FR2550945A1 (en) 1985-03-01
ES8606883A1 (en) 1986-05-01
IT8448757A0 (en) 1984-08-24
GB2147806B (en) 1986-10-22
HU191713B (en) 1987-03-30
JPH0556326B2 (en) 1993-08-19
NL8402515A (en) 1985-03-18
AT389228B (en) 1989-11-10
DE3448164C2 (en) 1987-06-25
FI843204A0 (en) 1984-08-14
KR880002223B1 (en) 1988-10-20
ZA846309B (en) 1985-03-27
FR2550945B1 (en) 1988-09-16
CH660125A5 (en) 1987-03-31
BE900377A (en) 1985-02-18
IT1177974B (en) 1987-09-03
FI843204A (en) 1985-02-27
DK389384A (en) 1985-02-27
SE8404090L (en) 1985-02-27
DK389384D0 (en) 1984-08-13
KR850001696A (en) 1985-04-01
NL192326C (en) 1997-06-04
IT8448757A1 (en) 1986-02-24
CA1225592A (en) 1987-08-18
JPS6072825A (en) 1985-04-24
ES535124A0 (en) 1986-05-01
GB2147806A (en) 1985-05-22
DE3431058A1 (en) 1985-03-07
IN157910B (en) 1986-07-19
DE3431058C2 (en) 1987-06-11
NO843243L (en) 1985-02-27
AU3221584A (en) 1985-02-28
NZ209233A (en) 1987-11-27
IL72675A (en) 1988-04-29
ATA273384A (en) 1989-04-15
NL192326B (en) 1997-02-03
AU554039B2 (en) 1986-08-07
SE8404090D0 (en) 1984-08-14

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20040813