KR850001696A - 온혈동물의 보조제 응답유도 또는 면역응답 자극방법 - Google Patents

온혈동물의 보조제 응답유도 또는 면역응답 자극방법 Download PDF

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Publication number
KR850001696A
KR850001696A KR1019840005189A KR840005189A KR850001696A KR 850001696 A KR850001696 A KR 850001696A KR 1019840005189 A KR1019840005189 A KR 1019840005189A KR 840005189 A KR840005189 A KR 840005189A KR 850001696 A KR850001696 A KR 850001696A
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South Korea
Prior art keywords
response
adjuvant
warm
induction
immune response
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KR1019840005189A
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English (en)
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KR880002223B1 (ko
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에른스트 리비 에드가
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닐스 에이. 리비
리비 이뮤노켐 리서어치 인코오퍼레이션
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Publication of KR850001696A publication Critical patent/KR850001696A/ko
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Publication of KR880002223B1 publication Critical patent/KR880002223B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

내용 없음

Description

온혈동물의 보조제 응답유도 또는 면역응답 자극방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 검출 불가능한 양의 2-케토-대옥시옥타노에이트와, 약 350내지 475nmoles/mg의 인과, 약 1700내지 2000nmoles/mg의 지방산을 함유하는 정제, 해독된 내독소를 약리적으로 사용가능한 담체와 조합하여 함유하는 조성물의 유효량을 투여함으로써 온혈동물의 유효보조제 응답을 유도하거나 면역응답을 자극하는 방법.
  2. 제1항에 있어서, 상기 유효량이 약 5내지 500㎍/kg인 것을 특징으로 하는 방법.
  3. 제2항에 있어서, 상기 유효량이 약 10내지 100㎍/kg인 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 조성물이 동결건조된 형태인 것을 특징으로 하는 방법.
  5. 제1항에 있어서, 조성물이 유점적 유제의 형태인 것을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840005189A 1983-08-26 1984-08-25 정제해독된 내독소 KR880002223B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52696783A 1983-08-26 1983-08-26
US526967 1983-08-26
US526,967 1983-08-26

Publications (2)

Publication Number Publication Date
KR850001696A true KR850001696A (ko) 1985-04-01
KR880002223B1 KR880002223B1 (ko) 1988-10-20

Family

ID=24099553

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840005189A KR880002223B1 (ko) 1983-08-26 1984-08-25 정제해독된 내독소

Country Status (22)

Country Link
JP (1) JPS6072825A (ko)
KR (1) KR880002223B1 (ko)
AT (1) AT389228B (ko)
AU (1) AU554039B2 (ko)
BE (1) BE900377A (ko)
CA (1) CA1225592A (ko)
CH (1) CH660125A5 (ko)
DE (2) DE3448164C2 (ko)
DK (1) DK389384A (ko)
ES (1) ES8606883A1 (ko)
FI (1) FI843204A (ko)
FR (1) FR2550945B1 (ko)
GB (1) GB2147806B (ko)
HU (1) HU191713B (ko)
IL (1) IL72675A (ko)
IN (1) IN157910B (ko)
IT (1) IT1177974B (ko)
NL (1) NL192326C (ko)
NO (1) NO843243L (ko)
NZ (1) NZ209233A (ko)
SE (1) SE8404090L (ko)
ZA (1) ZA846309B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100868443B1 (ko) * 2002-05-27 2008-11-11 주식회사 포스코 폭과 길이가 가변 조정되는 런치박스 제작장치

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629722A (en) * 1984-07-12 1986-12-16 Ribi Immunochem Research, Inc. Method of inhibiting the onset of acute radiation syndrome
US4806352A (en) * 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
US4803070A (en) * 1986-04-15 1989-02-07 Ribi Immunochem Research Inc. Immunological emulsion adjuvants for polysaccharide vaccines
DE10115310A1 (de) * 2001-03-28 2002-10-10 Nodar A Daniela Bakteriophagen-Präparation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160326B1 (ko) * 1971-11-19 1975-02-07 Anvar
BE793260A (fr) * 1971-12-24 1973-06-22 Pasteur Institut Agent immunostimulant, medicaments le contenant et procede de fabrication de cet agent immunostimulant
GB1516507A (en) * 1974-06-20 1978-07-05 Anvar Process for obtaining mycobacterial fractions with anti-tumor anti-viral and adjuvant activities and pharmaceutical compositions containing them
FR2393065A1 (fr) * 1977-05-31 1978-12-29 Merieux Inst Procede de separation de lipides d'endotoxines bacteriennes et notamment d'endotoxine de bordetella pertussis
US4435386A (en) * 1982-05-26 1984-03-06 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436728A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100868443B1 (ko) * 2002-05-27 2008-11-11 주식회사 포스코 폭과 길이가 가변 조정되는 런치박스 제작장치

Also Published As

Publication number Publication date
IT1177974B (it) 1987-09-03
FR2550945B1 (fr) 1988-09-16
DK389384A (da) 1985-02-27
NL192326B (nl) 1997-02-03
DK389384D0 (da) 1984-08-13
FR2550945A1 (fr) 1985-03-01
IT8448757A0 (it) 1984-08-24
DE3431058C2 (ko) 1987-06-11
IT8448757A1 (it) 1986-02-24
NL8402515A (nl) 1985-03-18
ES8606883A1 (es) 1986-05-01
ES535124A0 (es) 1986-05-01
AU554039B2 (en) 1986-08-07
IL72675A0 (en) 1984-11-30
FI843204A (fi) 1985-02-27
DE3448164C2 (ko) 1987-06-25
JPH0556326B2 (ko) 1993-08-19
SE8404090D0 (sv) 1984-08-14
HUT34887A (en) 1985-05-28
CA1225592A (en) 1987-08-18
IL72675A (en) 1988-04-29
KR880002223B1 (ko) 1988-10-20
GB8420612D0 (en) 1984-09-19
JPS6072825A (ja) 1985-04-24
NO843243L (no) 1985-02-27
GB2147806A (en) 1985-05-22
CH660125A5 (de) 1987-03-31
NZ209233A (en) 1987-11-27
NL192326C (nl) 1997-06-04
ZA846309B (en) 1985-03-27
GB2147806B (en) 1986-10-22
HU191713B (en) 1987-03-30
BE900377A (fr) 1985-02-18
AU3221584A (en) 1985-02-28
DE3431058A1 (de) 1985-03-07
IN157910B (ko) 1986-07-19
AT389228B (de) 1989-11-10
FI843204A0 (fi) 1984-08-14
SE8404090L (sv) 1985-02-27
ATA273384A (de) 1989-04-15

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