BE900377A - Endotoxine detoxifiee raffinee. - Google Patents

Endotoxine detoxifiee raffinee.

Info

Publication number
BE900377A
BE900377A BE0/213506A BE213506A BE900377A BE 900377 A BE900377 A BE 900377A BE 0/213506 A BE0/213506 A BE 0/213506A BE 213506 A BE213506 A BE 213506A BE 900377 A BE900377 A BE 900377A
Authority
BE
Belgium
Prior art keywords
detoxified endotoxin
refined detoxified
refined
response
stimulating
Prior art date
Application number
BE0/213506A
Other languages
English (en)
Inventor
E E Ribi
Original Assignee
Ribi Immunochem Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribi Immunochem Research Inc filed Critical Ribi Immunochem Research Inc
Publication of BE900377A publication Critical patent/BE900377A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composition susceptible de produire une réponse adjuvante efficase ou d'entrainer la stimulation de la réponse immunitaire d'un animal à sang chaud, caractérisée en ce qu'elle comprend une quantité efficace d'une matière du type endotoxine détoxifiée raffinée, en combinaison avec un véhicule ou excipient pharmaceutiquement acceptable.
BE0/213506A 1983-08-26 1984-08-17 Endotoxine detoxifiee raffinee. BE900377A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52696783A 1983-08-26 1983-08-26

Publications (1)

Publication Number Publication Date
BE900377A true BE900377A (fr) 1985-02-18

Family

ID=24099553

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213506A BE900377A (fr) 1983-08-26 1984-08-17 Endotoxine detoxifiee raffinee.

Country Status (22)

Country Link
JP (1) JPS6072825A (fr)
KR (1) KR880002223B1 (fr)
AT (1) AT389228B (fr)
AU (1) AU554039B2 (fr)
BE (1) BE900377A (fr)
CA (1) CA1225592A (fr)
CH (1) CH660125A5 (fr)
DE (2) DE3448164C2 (fr)
DK (1) DK389384A (fr)
ES (1) ES8606883A1 (fr)
FI (1) FI843204A (fr)
FR (1) FR2550945B1 (fr)
GB (1) GB2147806B (fr)
HU (1) HU191713B (fr)
IL (1) IL72675A (fr)
IN (1) IN157910B (fr)
IT (1) IT1177974B (fr)
NL (1) NL192326C (fr)
NO (1) NO843243L (fr)
NZ (1) NZ209233A (fr)
SE (1) SE8404090L (fr)
ZA (1) ZA846309B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629722A (en) * 1984-07-12 1986-12-16 Ribi Immunochem Research, Inc. Method of inhibiting the onset of acute radiation syndrome
US4803070A (en) * 1986-04-15 1989-02-07 Ribi Immunochem Research Inc. Immunological emulsion adjuvants for polysaccharide vaccines
US4806352A (en) * 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
DE10115310A1 (de) * 2001-03-28 2002-10-10 Nodar A Daniela Bakteriophagen-Präparation
KR100868443B1 (ko) * 2002-05-27 2008-11-11 주식회사 포스코 폭과 길이가 가변 조정되는 런치박스 제작장치

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160326B1 (fr) * 1971-11-19 1975-02-07 Anvar
BE793260A (fr) * 1971-12-24 1973-06-22 Pasteur Institut Agent immunostimulant, medicaments le contenant et procede de fabrication de cet agent immunostimulant
NL7507376A (nl) * 1974-06-20 1975-12-23 Anvar Werkwijze voor de bereiding van bacteriele prepa- raten met anti-tumor, antivirale en adjuvans-acti- viteiten.
FR2393065A1 (fr) * 1977-05-31 1978-12-29 Merieux Inst Procede de separation de lipides d'endotoxines bacteriennes et notamment d'endotoxine de bordetella pertussis
US4435386A (en) * 1982-05-26 1984-03-06 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436728A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product

Also Published As

Publication number Publication date
FR2550945B1 (fr) 1988-09-16
SE8404090L (sv) 1985-02-27
ES535124A0 (es) 1986-05-01
CA1225592A (fr) 1987-08-18
NO843243L (no) 1985-02-27
DE3448164C2 (fr) 1987-06-25
AU3221584A (en) 1985-02-28
ZA846309B (en) 1985-03-27
IT8448757A1 (it) 1986-02-24
ATA273384A (de) 1989-04-15
IT1177974B (it) 1987-09-03
KR880002223B1 (ko) 1988-10-20
IT8448757A0 (it) 1984-08-24
AU554039B2 (en) 1986-08-07
ES8606883A1 (es) 1986-05-01
DK389384A (da) 1985-02-27
JPH0556326B2 (fr) 1993-08-19
IL72675A (en) 1988-04-29
DK389384D0 (da) 1984-08-13
GB8420612D0 (en) 1984-09-19
NL8402515A (nl) 1985-03-18
AT389228B (de) 1989-11-10
DE3431058C2 (fr) 1987-06-11
FI843204A (fi) 1985-02-27
FI843204A0 (fi) 1984-08-14
KR850001696A (ko) 1985-04-01
NZ209233A (en) 1987-11-27
DE3431058A1 (de) 1985-03-07
GB2147806B (en) 1986-10-22
HU191713B (en) 1987-03-30
NL192326C (nl) 1997-06-04
JPS6072825A (ja) 1985-04-24
GB2147806A (en) 1985-05-22
IN157910B (fr) 1986-07-19
CH660125A5 (de) 1987-03-31
FR2550945A1 (fr) 1985-03-01
NL192326B (nl) 1997-02-03
IL72675A0 (en) 1984-11-30
HUT34887A (en) 1985-05-28
SE8404090D0 (sv) 1984-08-14

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: *RIBI IMMUNOCHEM RESEARCH INC.

Effective date: 20040817