CA1194487A - Dimemthylacetamide solvate of syn-(2- aminothiazol-4- yl) (methoxyimino) acetic acid - Google Patents

Dimemthylacetamide solvate of syn-(2- aminothiazol-4- yl) (methoxyimino) acetic acid

Info

Publication number
CA1194487A
CA1194487A CA000424616A CA424616A CA1194487A CA 1194487 A CA1194487 A CA 1194487A CA 000424616 A CA000424616 A CA 000424616A CA 424616 A CA424616 A CA 424616A CA 1194487 A CA1194487 A CA 1194487A
Authority
CA
Canada
Prior art keywords
solvate
syn
acetic acid
dimethylacetamide
aminothiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000424616A
Other languages
English (en)
French (fr)
Inventor
Robert W. Burchfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1194487A publication Critical patent/CA1194487A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000424616A 1982-04-01 1983-03-28 Dimemthylacetamide solvate of syn-(2- aminothiazol-4- yl) (methoxyimino) acetic acid Expired CA1194487A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US364,356 1982-04-01
US06/364,356 US4426528A (en) 1982-04-01 1982-04-01 Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid

Publications (1)

Publication Number Publication Date
CA1194487A true CA1194487A (en) 1985-10-01

Family

ID=23434150

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000424616A Expired CA1194487A (en) 1982-04-01 1983-03-28 Dimemthylacetamide solvate of syn-(2- aminothiazol-4- yl) (methoxyimino) acetic acid

Country Status (11)

Country Link
US (1) US4426528A (OSRAM)
EP (1) EP0091277B1 (OSRAM)
JP (1) JPS58183678A (OSRAM)
KR (1) KR840004090A (OSRAM)
CA (1) CA1194487A (OSRAM)
DE (1) DE3372096D1 (OSRAM)
DK (1) DK91383A (OSRAM)
GB (1) GB2119370B (OSRAM)
GR (1) GR79243B (OSRAM)
HU (1) HU186271B (OSRAM)
IL (1) IL68251A (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6124580A (ja) * 1984-07-12 1986-02-03 Shionogi & Co Ltd アミノチアゾリルグルタル酸誘導体の製造方法
EP1340751A4 (en) * 2000-12-04 2005-07-27 Fujisawa Pharmaceutical Co PROCESS FOR PRODUCING ANHYDRIDE OF AMINOTHIAZOLE DERIVATIVE
CN111548323B (zh) * 2020-05-29 2022-06-10 山东金城医药化工有限公司 氨噻肟酸的回收方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925372A (en) 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4152433A (en) 1976-03-12 1979-05-01 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
US4252951A (en) 1979-10-09 1981-02-24 Eli Lilly And Company Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid
DE3269474D1 (en) * 1981-11-13 1986-04-03 Glaxo Group Ltd Thiazole derivatives and their use in the manufacture of beta-lactam antibiotics

Also Published As

Publication number Publication date
US4426528A (en) 1984-01-17
DK91383D0 (da) 1983-02-25
GB2119370B (en) 1985-06-05
IL68251A0 (en) 1983-06-15
GB2119370A (en) 1983-11-16
HU186271B (en) 1985-07-29
DK91383A (da) 1983-10-02
EP0091277A2 (en) 1983-10-12
EP0091277B1 (en) 1987-06-16
IL68251A (en) 1986-03-31
GR79243B (OSRAM) 1984-10-22
JPS58183678A (ja) 1983-10-26
DE3372096D1 (en) 1987-07-23
KR840004090A (ko) 1984-10-06
EP0091277A3 (en) 1984-12-27

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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry