DE3372096D1 - Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid - Google Patents

Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid

Info

Publication number
DE3372096D1
DE3372096D1 DE8383301807T DE3372096T DE3372096D1 DE 3372096 D1 DE3372096 D1 DE 3372096D1 DE 8383301807 T DE8383301807 T DE 8383301807T DE 3372096 T DE3372096 T DE 3372096T DE 3372096 D1 DE3372096 D1 DE 3372096D1
Authority
DE
Germany
Prior art keywords
methoxyimino
syn
acetic acid
amino thiazol
dimethylacetamide solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383301807T
Other languages
English (en)
Inventor
Robert William Burchfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3372096D1 publication Critical patent/DE3372096D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8383301807T 1982-04-01 1983-03-30 Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid Expired DE3372096D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/364,356 US4426528A (en) 1982-04-01 1982-04-01 Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid

Publications (1)

Publication Number Publication Date
DE3372096D1 true DE3372096D1 (en) 1987-07-23

Family

ID=23434150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383301807T Expired DE3372096D1 (en) 1982-04-01 1983-03-30 Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid

Country Status (11)

Country Link
US (1) US4426528A (de)
EP (1) EP0091277B1 (de)
JP (1) JPS58183678A (de)
KR (1) KR840004090A (de)
CA (1) CA1194487A (de)
DE (1) DE3372096D1 (de)
DK (1) DK91383A (de)
GB (1) GB2119370B (de)
GR (1) GR79243B (de)
HU (1) HU186271B (de)
IL (1) IL68251A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6124580A (ja) * 1984-07-12 1986-02-03 Shionogi & Co Ltd アミノチアゾリルグルタル酸誘導体の製造方法
AU2002222553A1 (en) * 2000-12-04 2002-06-18 Fujisawa Pharmaceutical Co. Ltd. Process for producing anhydride of aminothiazole derivative
CN111548323B (zh) * 2020-05-29 2022-06-10 山东金城医药化工有限公司 氨噻肟酸的回收方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
EP0088847B1 (de) * 1981-11-13 1986-02-26 Glaxo Group Limited Thiazol-Derivate und ihre Verwendung bei der Herstellung von Beta-Lactam-Antibiotika

Also Published As

Publication number Publication date
EP0091277A2 (de) 1983-10-12
DK91383D0 (da) 1983-02-25
IL68251A0 (en) 1983-06-15
EP0091277B1 (de) 1987-06-16
GB2119370A (en) 1983-11-16
US4426528A (en) 1984-01-17
EP0091277A3 (en) 1984-12-27
KR840004090A (ko) 1984-10-06
GR79243B (de) 1984-10-22
DK91383A (da) 1983-10-02
JPS58183678A (ja) 1983-10-26
GB2119370B (en) 1985-06-05
HU186271B (en) 1985-07-29
CA1194487A (en) 1985-10-01
IL68251A (en) 1986-03-31

Similar Documents

Publication Publication Date Title
IL61227A (en) Solid solvate of syn-7-(2-amino-4-thiazolyl)(methoxyimino)-acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid and its isolation
IL65737A (en) 7-(2-(2-aminothiazol-4-yl)-2-oxy-iminoacetamido)-3-(1-pyridinium)methyl)ceph-3-em-4-carboxylate derivatives and pharmaceutical compositions comprising them
ZA824786B (en) Pharmaceutical compositions of bromhexine
DE3463494D1 (en) Process for the production of acetic acid and methyl acetate
IL71771A (en) Process for the preparation of 7-(2-(aminothiazolyl or aminothiadiazolyl)2-hydroxyiminoacetamido)-3-(ammoniomethyl)-ceph-3-em-4-carboxylate derivatives
PT83451A (pt) Process for the preparation of derivatives of quinoline benzothiazole and analogous thereof
PT74558B (en) Process for preparing antibiotics of the cephalosporin family
PT78778A (en) Process for preparing novel thiazolidine derivatives and of pharmaceutical compositions containing the same
GB2071654B (en) Hydroxamic acid derivatives of 7-(2-amino-4-thiazolyl)oximino cephalosporins
IL65307A0 (en) Process and intermediates for preparation of halomethyl esters(and related esters)of penicillanic acid 1,1-dioxide
DE3372096D1 (en) Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid
GB2083461B (en) 7-beta-(alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido)-3-((1,2,3-thiadiazol-5-ylthio)methyl)-3-cephem-4-carboxylic acid and c1-c6 alkyl derivatives thereof
AU532294B2 (en) Alkyloximes of 7-(2-amino-4-thiazolyl) - acetamido- cephalosporanic acids
DE3377649D1 (en) Process for the preparation of benzothiazolyl phenoxy-propionic-acid derivatives
CS647985A2 (en) Method of (z)-2-(2-amino-4-thiazolyl)-2-(esterified-carboxyimino)acetic acid's heterothioester production
JPS56131574A (en) Manufacture of hydrochloride of (2-aminothiazole-4-yl)-acetic acid
IT8267956A0 (it) Composizione per il trattamento del lupus eritematoso sistemico e glome rulonefrite primaria
IE830710L (en) (2-aminothiazol-4-yl) methoxyimino acetic acid derivatives
JPS5692292A (en) Nnsubstituted thiazolyl derivative of 77aminocephalosporanic acid
PT75139A (en) Process for the preparation of cephalosporanic acid derivatives and pharmaceutical compositions containing them
PT73092A (en) Process for the preparation of 2-(2-aminothiazol-4-yl)-n-(imidazolin-2-on-1-yl)-2-iminoacetyl-cephalosporinas in synform having anti-biotic properties
ZA838864B (en) Process for the manufacture of cephalosporin derivatives
DK119984A (da) Fremgangsmaade til fremstilling af 7-aminocephalosporansyrederivater
JPS57203028A (en) Manufacture of acetic acid
ZA791762B (en) New oxime derivatives of 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanic acid their preocess for preparation and the pharmaceutical compositions containing them

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee