CA1187488A - Ester indoleacetique derive et procede de preparation - Google Patents

Ester indoleacetique derive et procede de preparation

Info

Publication number
CA1187488A
CA1187488A CA000411293A CA411293A CA1187488A CA 1187488 A CA1187488 A CA 1187488A CA 000411293 A CA000411293 A CA 000411293A CA 411293 A CA411293 A CA 411293A CA 1187488 A CA1187488 A CA 1187488A
Authority
CA
Canada
Prior art keywords
group
lower alkyl
halogen atom
phenyl
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000411293A
Other languages
English (en)
Inventor
Yoichiro Ogawa
Kazuo Isomae
Kinichi Mogi
Susumu Sato
Tsukasa Kuwamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1509982A external-priority patent/JPS58134077A/ja
Priority claimed from JP5922982A external-priority patent/JPS58177966A/ja
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Application granted granted Critical
Publication of CA1187488A publication Critical patent/CA1187488A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
CA000411293A 1982-02-02 1982-09-13 Ester indoleacetique derive et procede de preparation Expired CA1187488A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP15099/1982 1982-02-02
JP1509982A JPS58134077A (ja) 1982-02-02 1982-02-02 新規なインド−ル酢酸エステル誘導体及びその製造法
JP5922982A JPS58177966A (ja) 1982-04-09 1982-04-09 新規なインド−ル酢酸エステル誘導体及びその製造法
JP59229/1982 1982-04-09

Publications (1)

Publication Number Publication Date
CA1187488A true CA1187488A (fr) 1985-05-21

Family

ID=26351190

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000411293A Expired CA1187488A (fr) 1982-02-02 1982-09-13 Ester indoleacetique derive et procede de preparation

Country Status (6)

Country Link
CA (1) CA1187488A (fr)
CH (1) CH649532A5 (fr)
DE (1) DE3235850A1 (fr)
FR (1) FR2520739B1 (fr)
GB (1) GB2125786B (fr)
IT (1) IT1149095B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6028957A (ja) * 1983-07-27 1985-02-14 Kaken Pharmaceut Co Ltd インドリル酢酸およびフエニル酢酸のエステル誘導体およびその製造法
US4619937A (en) * 1984-02-02 1986-10-28 Warner-Lambert Company Saturated bicyclic lactam acids and derivatives as cognition activators
US6762182B1 (en) 1999-01-07 2004-07-13 Vanderbilt University Converting cox inhibition compounds that are not COX-2 selective inhibitors to derivatives that are COX-2 selective inhibitors
US6207700B1 (en) 1999-01-07 2001-03-27 Vanderbilt University Amide derivatives for antiangiogenic and/or antitumorigenic use
US6306890B1 (en) 1999-08-30 2001-10-23 Vanderbilt University Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
EP1744747A4 (fr) 2004-04-26 2009-12-02 Univ Vanderbilt Derives d'acides indoleacetique et indenacetique comme agents therapeutiques a toxicite gastrointestinale reduite
WO2007149456A2 (fr) 2006-06-19 2007-12-27 Vanderbilt University Méthodes et compositions de diagnostic et de ciblage thérapeutique de cox-2
WO2013059245A1 (fr) 2011-10-17 2013-04-25 Vanderbilt University Analogues de l'indométacine destinés au traitement du cancer de la prostate résistant à la castration

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601228A5 (en) * 1977-06-17 1978-06-30 Hisamitsu Pharmaceutical Co Antiinflammatory indomethacin esters active topically and orally
BE871709A (fr) * 1978-10-31 1979-02-15 Abbott Lab Procede de preparation de composes doues d'une activite anti-inflammatoire

Also Published As

Publication number Publication date
CH649532A5 (de) 1985-05-31
FR2520739B1 (fr) 1985-07-12
FR2520739A1 (fr) 1983-08-05
GB2125786A (en) 1984-03-14
IT1149095B (it) 1986-12-03
GB2125786B (en) 1985-10-02
DE3235850A1 (de) 1983-08-11
IT8249205A0 (it) 1982-10-05

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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry