IT1149095B - Derivati di estere in dolacetico e procedimento per preparli - Google Patents

Derivati di estere in dolacetico e procedimento per preparli

Info

Publication number
IT1149095B
IT1149095B IT49205/82A IT4920582A IT1149095B IT 1149095 B IT1149095 B IT 1149095B IT 49205/82 A IT49205/82 A IT 49205/82A IT 4920582 A IT4920582 A IT 4920582A IT 1149095 B IT1149095 B IT 1149095B
Authority
IT
Italy
Prior art keywords
dolacetic
preparing
ester derivatives
derivatives
ester
Prior art date
Application number
IT49205/82A
Other languages
English (en)
Other versions
IT8249205A0 (it
Inventor
Susumu Sato
Kinichi Mogi
Kazuo Isomae
Yoichiro Ogawa
Tsukasa Kuwamura
Original Assignee
Ss Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1509982A external-priority patent/JPS58134077A/ja
Priority claimed from JP5922982A external-priority patent/JPS58177966A/ja
Application filed by Ss Pharmaceutical Co filed Critical Ss Pharmaceutical Co
Publication of IT8249205A0 publication Critical patent/IT8249205A0/it
Application granted granted Critical
Publication of IT1149095B publication Critical patent/IT1149095B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IT49205/82A 1982-02-02 1982-10-05 Derivati di estere in dolacetico e procedimento per preparli IT1149095B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1509982A JPS58134077A (ja) 1982-02-02 1982-02-02 新規なインド−ル酢酸エステル誘導体及びその製造法
JP5922982A JPS58177966A (ja) 1982-04-09 1982-04-09 新規なインド−ル酢酸エステル誘導体及びその製造法

Publications (2)

Publication Number Publication Date
IT8249205A0 IT8249205A0 (it) 1982-10-05
IT1149095B true IT1149095B (it) 1986-12-03

Family

ID=26351190

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49205/82A IT1149095B (it) 1982-02-02 1982-10-05 Derivati di estere in dolacetico e procedimento per preparli

Country Status (6)

Country Link
CA (1) CA1187488A (it)
CH (1) CH649532A5 (it)
DE (1) DE3235850A1 (it)
FR (1) FR2520739B1 (it)
GB (1) GB2125786B (it)
IT (1) IT1149095B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6028957A (ja) * 1983-07-27 1985-02-14 Kaken Pharmaceut Co Ltd インドリル酢酸およびフエニル酢酸のエステル誘導体およびその製造法
US4619937A (en) * 1984-02-02 1986-10-28 Warner-Lambert Company Saturated bicyclic lactam acids and derivatives as cognition activators
US6207700B1 (en) 1999-01-07 2001-03-27 Vanderbilt University Amide derivatives for antiangiogenic and/or antitumorigenic use
US6762182B1 (en) 1999-01-07 2004-07-13 Vanderbilt University Converting cox inhibition compounds that are not COX-2 selective inhibitors to derivatives that are COX-2 selective inhibitors
US6306890B1 (en) 1999-08-30 2001-10-23 Vanderbilt University Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
JP2007534702A (ja) 2004-04-26 2007-11-29 バンダービルト・ユニバーシティ 胃腸毒性の低い治療薬としてのインドール酢酸、及びインデン酢酸誘導体
CN101528222A (zh) 2006-06-19 2009-09-09 范德比尔特大学 用于诊断性和治疗性靶向cox-2的方法和组合物
EP3078374B1 (en) 2011-10-17 2019-06-19 Vanderbilt University Indomethacin analogs for the treatment of castrate-resistant prostate cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601228A5 (en) * 1977-06-17 1978-06-30 Hisamitsu Pharmaceutical Co Antiinflammatory indomethacin esters active topically and orally
BE871709A (fr) * 1978-10-31 1979-02-15 Abbott Lab Procede de preparation de composes doues d'une activite anti-inflammatoire

Also Published As

Publication number Publication date
FR2520739B1 (fr) 1985-07-12
FR2520739A1 (fr) 1983-08-05
GB2125786B (en) 1985-10-02
DE3235850A1 (de) 1983-08-11
IT8249205A0 (it) 1982-10-05
GB2125786A (en) 1984-03-14
CH649532A5 (de) 1985-05-31
CA1187488A (en) 1985-05-21

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