IT1149095B - Derivati di estere in dolacetico e procedimento per preparli - Google Patents
Derivati di estere in dolacetico e procedimento per preparliInfo
- Publication number
- IT1149095B IT1149095B IT49205/82A IT4920582A IT1149095B IT 1149095 B IT1149095 B IT 1149095B IT 49205/82 A IT49205/82 A IT 49205/82A IT 4920582 A IT4920582 A IT 4920582A IT 1149095 B IT1149095 B IT 1149095B
- Authority
- IT
- Italy
- Prior art keywords
- dolacetic
- preparing
- ester derivatives
- derivatives
- ester
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1509982A JPS58134077A (ja) | 1982-02-02 | 1982-02-02 | 新規なインド−ル酢酸エステル誘導体及びその製造法 |
JP5922982A JPS58177966A (ja) | 1982-04-09 | 1982-04-09 | 新規なインド−ル酢酸エステル誘導体及びその製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8249205A0 IT8249205A0 (it) | 1982-10-05 |
IT1149095B true IT1149095B (it) | 1986-12-03 |
Family
ID=26351190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49205/82A IT1149095B (it) | 1982-02-02 | 1982-10-05 | Derivati di estere in dolacetico e procedimento per preparli |
Country Status (6)
Country | Link |
---|---|
CA (1) | CA1187488A (it) |
CH (1) | CH649532A5 (it) |
DE (1) | DE3235850A1 (it) |
FR (1) | FR2520739B1 (it) |
GB (1) | GB2125786B (it) |
IT (1) | IT1149095B (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6028957A (ja) * | 1983-07-27 | 1985-02-14 | Kaken Pharmaceut Co Ltd | インドリル酢酸およびフエニル酢酸のエステル誘導体およびその製造法 |
US4619937A (en) * | 1984-02-02 | 1986-10-28 | Warner-Lambert Company | Saturated bicyclic lactam acids and derivatives as cognition activators |
US6762182B1 (en) | 1999-01-07 | 2004-07-13 | Vanderbilt University | Converting cox inhibition compounds that are not COX-2 selective inhibitors to derivatives that are COX-2 selective inhibitors |
US6207700B1 (en) | 1999-01-07 | 2001-03-27 | Vanderbilt University | Amide derivatives for antiangiogenic and/or antitumorigenic use |
US6306890B1 (en) | 1999-08-30 | 2001-10-23 | Vanderbilt University | Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors |
CN101031289A (zh) | 2004-04-26 | 2007-09-05 | 范德比尔特大学 | 作为具有降低胃肠毒性的治疗剂的吲哚乙酸和茚乙酸衍生物 |
CN101528222A (zh) | 2006-06-19 | 2009-09-09 | 范德比尔特大学 | 用于诊断性和治疗性靶向cox-2的方法和组合物 |
WO2013059245A1 (en) | 2011-10-17 | 2013-04-25 | Vanderbilt University | Indomethacin analogs for the treatment of castrate-resistant prostate cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH601228A5 (en) * | 1977-06-17 | 1978-06-30 | Hisamitsu Pharmaceutical Co | Antiinflammatory indomethacin esters active topically and orally |
BE871709A (fr) * | 1978-10-31 | 1979-02-15 | Abbott Lab | Procede de preparation de composes doues d'une activite anti-inflammatoire |
-
1982
- 1982-09-13 CA CA000411293A patent/CA1187488A/en not_active Expired
- 1982-09-20 GB GB08226787A patent/GB2125786B/en not_active Expired
- 1982-09-28 DE DE19823235850 patent/DE3235850A1/de not_active Ceased
- 1982-10-05 IT IT49205/82A patent/IT1149095B/it active
- 1982-11-19 CH CH6750/82A patent/CH649532A5/de not_active IP Right Cessation
- 1982-12-03 FR FR8220317A patent/FR2520739B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT8249205A0 (it) | 1982-10-05 |
FR2520739A1 (fr) | 1983-08-05 |
CH649532A5 (de) | 1985-05-31 |
GB2125786B (en) | 1985-10-02 |
FR2520739B1 (fr) | 1985-07-12 |
CA1187488A (en) | 1985-05-21 |
DE3235850A1 (de) | 1983-08-11 |
GB2125786A (en) | 1984-03-14 |
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