GB2125786B - Esters of indomethacin - Google Patents
Esters of indomethacinInfo
- Publication number
- GB2125786B GB2125786B GB08226787A GB8226787A GB2125786B GB 2125786 B GB2125786 B GB 2125786B GB 08226787 A GB08226787 A GB 08226787A GB 8226787 A GB8226787 A GB 8226787A GB 2125786 B GB2125786 B GB 2125786B
- Authority
- GB
- United Kingdom
- Prior art keywords
- indomethacin
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1509982A JPS58134077A (en) | 1982-02-02 | 1982-02-02 | Novel indoleacetic ester derivative and preparation thereof |
JP5922982A JPS58177966A (en) | 1982-04-09 | 1982-04-09 | Novel indoleacetic ester derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2125786A GB2125786A (en) | 1984-03-14 |
GB2125786B true GB2125786B (en) | 1985-10-02 |
Family
ID=26351190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08226787A Expired GB2125786B (en) | 1982-02-02 | 1982-09-20 | Esters of indomethacin |
Country Status (6)
Country | Link |
---|---|
CA (1) | CA1187488A (en) |
CH (1) | CH649532A5 (en) |
DE (1) | DE3235850A1 (en) |
FR (1) | FR2520739B1 (en) |
GB (1) | GB2125786B (en) |
IT (1) | IT1149095B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6028957A (en) * | 1983-07-27 | 1985-02-14 | Kaken Pharmaceut Co Ltd | Ester derivatives of indolylacetic acid and phenylacetic acid and their production |
US4619937A (en) * | 1984-02-02 | 1986-10-28 | Warner-Lambert Company | Saturated bicyclic lactam acids and derivatives as cognition activators |
US6762182B1 (en) | 1999-01-07 | 2004-07-13 | Vanderbilt University | Converting cox inhibition compounds that are not COX-2 selective inhibitors to derivatives that are COX-2 selective inhibitors |
US6207700B1 (en) | 1999-01-07 | 2001-03-27 | Vanderbilt University | Amide derivatives for antiangiogenic and/or antitumorigenic use |
US6306890B1 (en) | 1999-08-30 | 2001-10-23 | Vanderbilt University | Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors |
CN101031289A (en) | 2004-04-26 | 2007-09-05 | 范德比尔特大学 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity |
CN101528222A (en) | 2006-06-19 | 2009-09-09 | 范德比尔特大学 | Methods and compositions for diagnostic and therapeutic targeting of COX-2 |
WO2013059245A1 (en) | 2011-10-17 | 2013-04-25 | Vanderbilt University | Indomethacin analogs for the treatment of castrate-resistant prostate cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH601228A5 (en) * | 1977-06-17 | 1978-06-30 | Hisamitsu Pharmaceutical Co | Antiinflammatory indomethacin esters active topically and orally |
BE871709A (en) * | 1978-10-31 | 1979-02-15 | Abbott Lab | PROCESS FOR PREPARATION OF COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY |
-
1982
- 1982-09-13 CA CA000411293A patent/CA1187488A/en not_active Expired
- 1982-09-20 GB GB08226787A patent/GB2125786B/en not_active Expired
- 1982-09-28 DE DE19823235850 patent/DE3235850A1/en not_active Ceased
- 1982-10-05 IT IT49205/82A patent/IT1149095B/en active
- 1982-11-19 CH CH6750/82A patent/CH649532A5/en not_active IP Right Cessation
- 1982-12-03 FR FR8220317A patent/FR2520739B1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT8249205A0 (en) | 1982-10-05 |
FR2520739A1 (en) | 1983-08-05 |
CH649532A5 (en) | 1985-05-31 |
IT1149095B (en) | 1986-12-03 |
FR2520739B1 (en) | 1985-07-12 |
CA1187488A (en) | 1985-05-21 |
DE3235850A1 (en) | 1983-08-11 |
GB2125786A (en) | 1984-03-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB8326029D0 (en) | Esters | |
DE3365701D1 (en) | Preparation of esters | |
DE3366133D1 (en) | Transesterification of esters | |
GB8320518D0 (en) | Cefuroxime ester | |
GB8408815D0 (en) | Derivatives of azet-2-ones | |
DE3361480D1 (en) | Difluoromethoxyphenylthiophosphoric-acid esters | |
GB8317388D0 (en) | Interior of pipes | |
GB2131196B (en) | Alignment of objects | |
GB8305828D0 (en) | Ethylmethylthio substituted alkyl esters | |
IE831272L (en) | Ester of metronidazole | |
GB2084156B (en) | Esterification of a-l-aspartyl-l-phenylalanine | |
GB8333670D0 (en) | Generation of signals | |
GB2125786B (en) | Esters of indomethacin | |
GB2129426B (en) | Compounds of thiatriazines | |
GB2129905B (en) | Set of angle brackets | |
MY8700194A (en) | Carbamic-acid esters | |
JPS5794042A (en) | Carbazolization of anthrimide | |
DE3360020D1 (en) | Fungicide-active derivatives of benzhydrole | |
GB2123822B (en) | The preparations of indoles | |
GB8510717D0 (en) | Ester | |
GB8310144D0 (en) | Substituted derivatives of thia-morpholinone | |
GB8304857D0 (en) | Manufacture of nitrophenetoles | |
ZA831886B (en) | Halogenated esters | |
GB8314001D0 (en) | Preparation of alphahaloalkyl esters | |
ZA832380B (en) | Sanitere en/of onmatige voering |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |