CA1174979A - Anticonvulsive compositions and method of treating convulsive disorders - Google Patents

Anticonvulsive compositions and method of treating convulsive disorders

Info

Publication number
CA1174979A
CA1174979A CA000380072A CA380072A CA1174979A CA 1174979 A CA1174979 A CA 1174979A CA 000380072 A CA000380072 A CA 000380072A CA 380072 A CA380072 A CA 380072A CA 1174979 A CA1174979 A CA 1174979A
Authority
CA
Canada
Prior art keywords
composition
acid
compound
amino
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000380072A
Other languages
English (en)
French (fr)
Inventor
Stanley Samuels
Stephen A. Schwartz
Irving Fish
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
Original Assignee
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/162,907 external-priority patent/US4322440A/en
Application filed by New York University NYU filed Critical New York University NYU
Application granted granted Critical
Publication of CA1174979A publication Critical patent/CA1174979A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000380072A 1980-06-25 1981-06-18 Anticonvulsive compositions and method of treating convulsive disorders Expired CA1174979A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/162,907 US4322440A (en) 1980-06-25 1980-06-25 Anticonvulsive compositions and method of treating convulsive disorders
US162,907 1980-06-25
US06/269,629 US4372974A (en) 1980-06-25 1981-06-02 Anticonvulsive compositions and method of treating convulsive disorders
US269,629 1981-06-02

Publications (1)

Publication Number Publication Date
CA1174979A true CA1174979A (en) 1984-09-25

Family

ID=26859151

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000380072A Expired CA1174979A (en) 1980-06-25 1981-06-18 Anticonvulsive compositions and method of treating convulsive disorders

Country Status (5)

Country Link
US (1) US4372974A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0042626B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1174979A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3174659D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL63158A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU84891A1 (fr) * 1983-06-30 1985-03-29 Continental Pharma Derives de l'acide 2-aminoacetique,leur preparation et utilisation ainsi que compositions pharmaceutiques contenant ces derives
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
US5378729A (en) 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5654301A (en) * 1985-02-15 1997-08-05 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
EP0236734A3 (de) * 1986-02-07 1988-05-11 Ciba-Geigy Ag Durch schwefelhaltigen Gruppen substituierte 5-Amino-4-hydroxyvalerylderivate
ATE86971T1 (de) * 1986-08-13 1993-04-15 Ciba Geigy Ag Verfahren zur herstellung von 5-amino-4hydroxyvalerians|ure-derivaten.
NZ222045A (en) * 1986-08-21 1989-10-27 Res Corp Technologies Inc From diamides up to tetrapeptides for use as anticanvulsants
US4758584A (en) * 1987-02-05 1988-07-19 Ciba-Geigy Corporation Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups
US4816259A (en) * 1987-02-12 1989-03-28 Chase Chemical Company, L.P. Process for coating gelatin capsules
DE3924705A1 (de) * 1989-07-26 1991-01-31 Boehringer Mannheim Gmbh Heterobifunktionelle verbindungen
US6197819B1 (en) * 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
HUP0101419A3 (en) 1998-04-16 2002-08-28 Texas Biotechnology Corp Houst Compounds that inhibit the binding of integrins to their receptors and pharmaceutical compositions containing them
JP4634585B2 (ja) 2000-08-10 2011-02-16 昭和シェル石油株式会社 防錆性および耐摩耗性が改良されたグリース組成物
JP4619558B2 (ja) * 2001-03-23 2011-01-26 株式会社コスモ総合研究所 ５−アミノ−４−ヒドロキシペンタン酸誘導体とその製造方法
DE10252413A1 (de) * 2002-11-12 2004-05-27 Degussa Ag Verfahren zur Herstellung von Lösungen von Alkalimetallsalzen funktionalisierter Alkohole
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
JP5034032B2 (ja) * 2004-09-29 2012-09-26 Ｓｂｉファーマ株式会社 腫瘍診断剤
CN116947670B (zh) * 2023-04-13 2025-07-11 广东省农业科学院茶叶研究所 一种化合物及其在毛叶茶品种鉴别中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE673604A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) *
US3323995A (en) * 1963-05-20 1967-06-06 Univ Northwestern Method of inhibiting the crosslinking of fibrin in blood
LU53029A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1967-02-21 1968-08-27
US3629451A (en) * 1969-03-03 1971-12-21 Stanley Drug Products Inc Method of treating bacterial infections
US3960927A (en) * 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique

Also Published As

Publication number Publication date
US4372974B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1985-11-12
DE3174659D1 (en) 1986-06-26
IL63158A (en) 1985-06-30
US4372974A (en) 1983-02-08
EP0042626A3 (en) 1982-04-28
EP0042626A2 (en) 1981-12-30
EP0042626B1 (en) 1986-05-21

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